中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
11期
943-946
,共4页
前列腺增生%前列腺特异抗原
前列腺增生%前列腺特異抗原
전렬선증생%전렬선특이항원
Prostatic hyperplasia%Prostate-specific antigen
目的 研究老年人良性前列腺增生(BPH)的诊断治疗情况. 方法 以2010年1月至2012年3月在干部门诊体检的188例保健干部为对象,对其进行腹部超声检查测定前列腺体积(PV),以PV≥20 ml诊断BPH；国际前列腺症状评分(IPSS)评估下尿路症状；测定血清前列腺特异性抗原(PSA),将年龄≥62岁、PSA≥1.6 μg/L、PV≥31 ml诊断为高进展性BPH.分析老年人BPH患病率、知晓率及治疗情况,单因素方差分析比较不同年龄组的PV、IPSS及PSA浓度,Logistic回归分析BPH的危险因素. 结果 188例老年人BPH的患病率为48.4％ (91/188),知晓率41.5％(78/188),但因下尿路症状而就诊知晓的为10.6％ (20/188)；PV、IPSS、PSA浓度随增龄而增加(均P＜0.01),年龄、高血压及糖尿病是BPH的危险因素；BPH患者中以5α还原酶抑制剂为主进行药物治疗的占47.3％,46例高进展BPH患者中有10例未使用药物治疗. 结论 BPH患病率随增龄而增加,老年人对下尿路症状不够重视导致主动就诊率低,临床医师对高进展性BPH药物治疗不及时,应在老年、高血压和糖尿病患者中加强BPH宣教及筛查,采取综合性治疗措施.
目的 研究老年人良性前列腺增生(BPH)的診斷治療情況. 方法 以2010年1月至2012年3月在榦部門診體檢的188例保健榦部為對象,對其進行腹部超聲檢查測定前列腺體積(PV),以PV≥20 ml診斷BPH；國際前列腺癥狀評分(IPSS)評估下尿路癥狀；測定血清前列腺特異性抗原(PSA),將年齡≥62歲、PSA≥1.6 μg/L、PV≥31 ml診斷為高進展性BPH.分析老年人BPH患病率、知曉率及治療情況,單因素方差分析比較不同年齡組的PV、IPSS及PSA濃度,Logistic迴歸分析BPH的危險因素. 結果 188例老年人BPH的患病率為48.4％ (91/188),知曉率41.5％(78/188),但因下尿路癥狀而就診知曉的為10.6％ (20/188)；PV、IPSS、PSA濃度隨增齡而增加(均P＜0.01),年齡、高血壓及糖尿病是BPH的危險因素；BPH患者中以5α還原酶抑製劑為主進行藥物治療的佔47.3％,46例高進展BPH患者中有10例未使用藥物治療. 結論 BPH患病率隨增齡而增加,老年人對下尿路癥狀不夠重視導緻主動就診率低,臨床醫師對高進展性BPH藥物治療不及時,應在老年、高血壓和糖尿病患者中加彊BPH宣教及篩查,採取綜閤性治療措施.
목적 연구노년인량성전렬선증생(BPH)적진단치료정황. 방법 이2010년1월지2012년3월재간부문진체검적188례보건간부위대상,대기진행복부초성검사측정전렬선체적(PV),이PV≥20 ml진단BPH；국제전렬선증상평분(IPSS)평고하뇨로증상；측정혈청전렬선특이성항원(PSA),장년령≥62세、PSA≥1.6 μg/L、PV≥31 ml진단위고진전성BPH.분석노년인BPH환병솔、지효솔급치료정황,단인소방차분석비교불동년령조적PV、IPSS급PSA농도,Logistic회귀분석BPH적위험인소. 결과 188례노년인BPH적환병솔위48.4％ (91/188),지효솔41.5％(78/188),단인하뇨로증상이취진지효적위10.6％ (20/188)；PV、IPSS、PSA농도수증령이증가(균P＜0.01),년령、고혈압급당뇨병시BPH적위험인소；BPH환자중이5α환원매억제제위주진행약물치료적점47.3％,46례고진전BPH환자중유10례미사용약물치료. 결론 BPH환병솔수증령이증가,노년인대하뇨로증상불구중시도치주동취진솔저,림상의사대고진전성BPH약물치료불급시,응재노년、고혈압화당뇨병환자중가강BPH선교급사사,채취종합성치료조시.
Objective To evaluate the diagnostic and therapeutic status of elderly benign prostatic hyperplasia (BPH).Methods Totally 188 male elderly in outpatient department from January 2010 to March 2012 were enrolled in this study.Medical history was inquired in detail,and prostatic volumes (PV)were measured by abdominal ultrasound,PV≥ 20ml was diagnosed as BPH.Lower urinary tract symptoms (LUTS) was evaluated by international prostate symptom score (IPSS),prostate specific antigen (PSA) was measured.Age≥62 years,PSA≥1.6 μg/L and PV≥31 ml were considered as higher risk of clinical progression of BPH.We investigated the rate of prevalence,awareness and treatment of BPH.PV,IPSS and PSA were compared among different age groups by ANOVA.Logistic regression analysis was made to show the risk factors of BPH.Results Among 188 male elderly,the prevalence rate of BPH was 48.4％,and the total rate of awareness was 41.5％.The rate of awareness resulting from seeing doctor due to LUTS was 10.6％.PV,IPSS and PSA were increased with ageing.Risk factors contributing to BPH were age,hypertension and diabetes.The treatment rate with drugs of 5a-reductase inhibitor was 47.3 ％,however 10 subjects had not been given drugs treatment among 46 patients with higher risk of clinical progression of BPH.Conclusions The prevalence rate of BPH is increased with ageing,the proportion of seeing a doctor with passion is lower because the male elderly have not paid enough attention to LUTS.And doctors have not given drugs intervention to patients with clinical progression BPH in time.We should launch propaganda and education among the elderly patients with hypertension and diabetes and take comprehensive treatment.
