中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
1期
28-32
,共5页
廖晓艳%牧本清子%山川みやえ%釜江和惠%周藤俊智%蔡文智
廖曉豔%牧本清子%山川みやえ%釜江和惠%週籐俊智%蔡文智
료효염%목본청자%산천みやえ%부강화혜%주등준지%채문지
阿尔茨海默病%痴呆%行为症状
阿爾茨海默病%癡呆%行為癥狀
아이자해묵병%치태%행위증상
Alzheimer disease%Dementia%Behavioral symptoms
目的 比较阿尔茨海默病与额颞叶痴呆徘徊者夜间徘徊行为的差异. 方法 选取2008年9月至2009年9月入住大阪浅香山医院认知障碍病房的痴呆住院患者,其中27例阿尔茨海默病及7例额颞叶痴呆徘徊者符合纳入标准,利用电子示踪监测系统对受试者步行活动进行为期30d的连续监测和记录,并比较两组受试者日、夜步行活动水平(6∶00～23∶59及0∶00～5∶59的步行距离)、夜间步行活动频度(夜间有步行活动的天数与观察总天数的比值)和强度(夜间步行活动的时数与观察总时数的比值)的差异. 结果 阿尔茨海默病组患者年龄(73.9±9.1)岁,较额颞叶痴呆组患者(63.4±14.9)岁年龄大(t=5.56,P＜0.05),且发病年龄晚[(70.2±9.3)岁与(58.2±15.2)岁,t=6.30,P＜0.05].阿尔茨海默病组日间步行活动水平低于额颞叶痴呆组[(2119.39±2535.59)m与(4842.44±2617.94)m,z=2.66,P=0.01],但两组夜间步行活动的水平、频度及强度差异均无统计学意义(P＞0.05).与额叶变异型额颞叶痴呆徘徊者的进一步比较显示,阿尔茨海默病徘徊者的日间步行活动水平较低[(2119.39±2535.59)m与(4151.96±1881.35)m,z=2.10,P＜0.05],但夜间步行活动水平[(85.17±142.42)m与(1.19±1.71)m]、频度(0.64±0.29与0.33±0.22)及强度(0.21±0.13与0.07±0.05)均明显增高(z=2.11,t=2.05、2.39,均P＜0.05). 结论 与额颞叶痴呆徘徊者相比,阿尔茨海默病徘徊者日间步行活动水平较低,但其夜间步行活动水平、频度和强度均高于额叶变异型额颞叶痴呆徘徊者,提示对阿尔茨海默病徘徊者需要加强夜间徘徊行为的管理和临床干预.
目的 比較阿爾茨海默病與額顳葉癡呆徘佪者夜間徘佪行為的差異. 方法 選取2008年9月至2009年9月入住大阪淺香山醫院認知障礙病房的癡呆住院患者,其中27例阿爾茨海默病及7例額顳葉癡呆徘佪者符閤納入標準,利用電子示蹤鑑測繫統對受試者步行活動進行為期30d的連續鑑測和記錄,併比較兩組受試者日、夜步行活動水平(6∶00～23∶59及0∶00～5∶59的步行距離)、夜間步行活動頻度(夜間有步行活動的天數與觀察總天數的比值)和彊度(夜間步行活動的時數與觀察總時數的比值)的差異. 結果 阿爾茨海默病組患者年齡(73.9±9.1)歲,較額顳葉癡呆組患者(63.4±14.9)歲年齡大(t=5.56,P＜0.05),且髮病年齡晚[(70.2±9.3)歲與(58.2±15.2)歲,t=6.30,P＜0.05].阿爾茨海默病組日間步行活動水平低于額顳葉癡呆組[(2119.39±2535.59)m與(4842.44±2617.94)m,z=2.66,P=0.01],但兩組夜間步行活動的水平、頻度及彊度差異均無統計學意義(P＞0.05).與額葉變異型額顳葉癡呆徘佪者的進一步比較顯示,阿爾茨海默病徘佪者的日間步行活動水平較低[(2119.39±2535.59)m與(4151.96±1881.35)m,z=2.10,P＜0.05],但夜間步行活動水平[(85.17±142.42)m與(1.19±1.71)m]、頻度(0.64±0.29與0.33±0.22)及彊度(0.21±0.13與0.07±0.05)均明顯增高(z=2.11,t=2.05、2.39,均P＜0.05). 結論 與額顳葉癡呆徘佪者相比,阿爾茨海默病徘佪者日間步行活動水平較低,但其夜間步行活動水平、頻度和彊度均高于額葉變異型額顳葉癡呆徘佪者,提示對阿爾茨海默病徘佪者需要加彊夜間徘佪行為的管理和臨床榦預.
목적 비교아이자해묵병여액섭협치태배회자야간배회행위적차이. 방법 선취2008년9월지2009년9월입주대판천향산의원인지장애병방적치태주원환자,기중27례아이자해묵병급7례액섭협치태배회자부합납입표준,이용전자시종감측계통대수시자보행활동진행위기30d적련속감측화기록,병비교량조수시자일、야보행활동수평(6∶00～23∶59급0∶00～5∶59적보행거리)、야간보행활동빈도(야간유보행활동적천수여관찰총천수적비치)화강도(야간보행활동적시수여관찰총시수적비치)적차이. 결과 아이자해묵병조환자년령(73.9±9.1)세,교액섭협치태조환자(63.4±14.9)세년령대(t=5.56,P＜0.05),차발병년령만[(70.2±9.3)세여(58.2±15.2)세,t=6.30,P＜0.05].아이자해묵병조일간보행활동수평저우액섭협치태조[(2119.39±2535.59)m여(4842.44±2617.94)m,z=2.66,P=0.01],단량조야간보행활동적수평、빈도급강도차이균무통계학의의(P＞0.05).여액협변이형액섭협치태배회자적진일보비교현시,아이자해묵병배회자적일간보행활동수평교저[(2119.39±2535.59)m여(4151.96±1881.35)m,z=2.10,P＜0.05],단야간보행활동수평[(85.17±142.42)m여(1.19±1.71)m]、빈도(0.64±0.29여0.33±0.22)급강도(0.21±0.13여0.07±0.05)균명현증고(z=2.11,t=2.05、2.39,균P＜0.05). 결론 여액섭협치태배회자상비,아이자해묵병배회자일간보행활동수평교저,단기야간보행활동수평、빈도화강도균고우액협변이형액섭협치태배회자,제시대아이자해묵병배회자수요가강야간배회행위적관리화림상간예.
Objective To delineate the differences in nocturnal wandering behavior between patients with Alzheimer's disease (AD) and with frontotemporal dementia (FTD).Methods The study was conducted in a dementia care unit at a hospital in Osaka,Japan from September 2008 to September 2009.Twenty-four-hour movements of 27 ambulatory inpatients with AD and 7 inpatients with FTD were recorded consecutively by the IC tag monitoring system.Results There were no significant differences in the distribution of sex,duration of dementia,clinical dementia rating (CDR) and mini-mental state examination (MMSE) scores between two dementia types.However,patients with FTD were much younger than those with AD [(63.43± 14.93) yr vs.(73.89 ±9.12) yr,t=5.56,P＜0.05],and age of onset were significantly different between two dementia types [(58.17±15.16) yr vs.(70.16±9.26) yr,t=6.30,P＜0.05].There was increased distances moved during 6∶ 00-23 ∶ 59 in FTD group comparing with AD group [(4842.44 ± 2617.94)m vs.(2119.39 ±2535.59)m,Z=2.66,P＜0.01],while difference in distances moved during 0 ∶ 00-5 ∶ 59,frequency and intensity of nocturnal ambulation were not significant(P＞0.05)between two groups.Further study showed that AD wanderers had longer distance moved during 0 ∶ 00-5 ∶ 59 [(85.17±142.42)m vs.(1.19±1.71)m] with shorter distance moved during 6 ∶ 00-23 ∶ 59 [(2119.39±2535.59)m vs.(4151.96±1881.35)m],and increased frequency [(0.64±0.29) vs.(0.33±0.22)] and intensity of nocturnal ambulation [(0.21±0.13) vs.(0.07±0.05)],compared with those with frontal variant FTD (all P＜0.05).Conclusions AD patients have more severe nocturnal ambulation than those with frontal variant FTD,which suggests that the increased monitoring and clinical interventions during nighttime should be taken for AD wanderers.
