CAJ | 학술논문

目的系统评价B超检测膀胱内前列腺突出(IPP)≥10 mm时诊断良性前列腺增生(BPH)患者膀胱出口梗阻的准确度. 方法检索Medline、Embase、重庆维普、中国期刊全文数据库(CNKI)4个数据库,由2名系统评价员进行独立文献筛查及数据提取,采用QUADAD量表行质量评价,以尿流动力学测定的膀胱出口梗阻指数(BOOI)为金标准(BOOI＞40提示存在膀胱出口梗阻),使用Meta-disc 1.4软件进行异质性检验、数据分析和完成SROC曲线. 结果最终纳入6篇文献,包括受检者682例,异质性检验提示无阈值效应,但存在其他因素导致的异质性,采用随机效应模型.经合成后的敏感度为70.8％,特异度87.6％,阳性似然比5.132,阴性似然比0.303,诊断性比值比22.18；SROC曲线下面积为0.8723,Q点0.8028. 结论应用B超检测IPP可有效检测BPH患者是否存在膀胱出口梗阻.
목적 계통평개B초검측방광내전렬선돌출(IPP)≥10 mm시진단량성전렬선증생(BPH)환자방광출구경조적준학도. 방법 검색Medline、Embase、중경유보、중국기간전문수거고(CNKI)4개수거고,유2명계통평개원진행독립문헌사사급수거제취,채용QUADAD량표행질량평개,이뇨류동역학측정적방광출구경조지수(BOOI)위금표준(BOOI＞40제시존재방광출구경조),사용Meta-disc 1.4연건진행이질성검험、수거분석화완성SROC곡선. 결과 최종납입6편문헌,포괄수검자682례,이질성검험제시무역치효응,단존재기타인소도치적이질성,채용수궤효응모형.경합성후적민감도위70.8％,특이도87.6％,양성사연비5.132,음성사연비0.303,진단성비치비22.18；SROC곡선하면적위0.8723,Q점0.8028. 결론 응용B초검측IPP가유효검측BPH환자시부존재방광출구경조.
protrusion measured by ultrasound for diagnosing bladder outlet obstruction.Methods A literature search of medline (1966.1-2011.6),embase(1984.1-2011.6),CNKI (1994.1-2011.6) and WEIPU Data (1989.1-2011.6) from 1999 to 2009 was performed by two reviewers independently.QUADAS items was applicated to assess trial quality.Golden standard was BOOI measured by urodynamics (BOOI more than 40 indicates bladder outlet obstruction).Heterogenous studies and meta-analysis were conducted by Meta-Disc 1.4 software.Results Totally 6 studies was included at last,involving 682 subjects.No threshold effect was found,but there was heterogeneity due to other factors.The meta-analysis showed that the sensitivity was 70.8 ％,specificity was 87.6 ％,positive LR was 5.132,negative LR was 0.303,the diagnostic OR was 22.18,the area under SROC curve was 0.8723 and Q index was 0.8028.Conclusions Intravesical prostatic protrusion measured by ultrasound is a good index for diagnosing bladder outlet obstruction in patients with benign prostate hyperplasia when intravesical prostatic protrusion is equal or more than 10mm.