中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
2期
135-137
,共3页
阿力木江·阿不力米提%马金萍
阿力木江·阿不力米提%馬金萍
아력목강·아불력미제%마금평
利钠肽,脑%冠状动脉疾病%心脏功能试验
利鈉肽,腦%冠狀動脈疾病%心髒功能試驗
리납태,뇌%관상동맥질병%심장공능시험
Natriuretic peptide,brain%Coronary artery disease%Heart function tests
目的 探讨老年急性心肌梗死患者血浆脑利钠肽(BNP)的水平及其与入院时心功能的关系. 方法 入选新疆喀什地区第二人民医院内二科2008年12月至2010年8月确诊的老年急性心肌梗死患者100例,年龄60～97岁,平均(71.1±3.8)岁；男性62例,女性38例.按急性心肌梗死的Killip's心功能分级将患者分为4组,Ⅰ级、Ⅱ级、Ⅲ级和Ⅳ级组分别为24例、32例、23例、21例.测量左心房直径(LAD)、左心室收缩末径(LVESD)、左心室舒张末径(LVEDD),以改良Simpson法测量左心室射血分数(LVEF).酶联免疫法测定血浆BNP. 结果 4组患者LVESD、LVEDD、LVEF、BNP和logBNP等指标比较,差异有统计学意义(F值分别为7.21、10.70、11.12、19.70、74.21,P＜0.05或P＜0.01).血浆BNP浓度与LVESD(r=0.27,P＜0.01)、LVEDD (r=0.37,P＜0.01)呈正相关；与LVEF呈负相关(r=-0.38,P＜0.01). 结论 急性心肌梗死老年患者的心功能下降,BNP可评价老年急性心肌梗死患者的心功能.
目的 探討老年急性心肌梗死患者血漿腦利鈉肽(BNP)的水平及其與入院時心功能的關繫. 方法 入選新疆喀什地區第二人民醫院內二科2008年12月至2010年8月確診的老年急性心肌梗死患者100例,年齡60～97歲,平均(71.1±3.8)歲；男性62例,女性38例.按急性心肌梗死的Killip's心功能分級將患者分為4組,Ⅰ級、Ⅱ級、Ⅲ級和Ⅳ級組分彆為24例、32例、23例、21例.測量左心房直徑(LAD)、左心室收縮末徑(LVESD)、左心室舒張末徑(LVEDD),以改良Simpson法測量左心室射血分數(LVEF).酶聯免疫法測定血漿BNP. 結果 4組患者LVESD、LVEDD、LVEF、BNP和logBNP等指標比較,差異有統計學意義(F值分彆為7.21、10.70、11.12、19.70、74.21,P＜0.05或P＜0.01).血漿BNP濃度與LVESD(r=0.27,P＜0.01)、LVEDD (r=0.37,P＜0.01)呈正相關；與LVEF呈負相關(r=-0.38,P＜0.01). 結論 急性心肌梗死老年患者的心功能下降,BNP可評價老年急性心肌梗死患者的心功能.
목적 탐토노년급성심기경사환자혈장뇌리납태(BNP)적수평급기여입원시심공능적관계. 방법 입선신강객십지구제이인민의원내이과2008년12월지2010년8월학진적노년급성심기경사환자100례,년령60～97세,평균(71.1±3.8)세；남성62례,녀성38례.안급성심기경사적Killip's심공능분급장환자분위4조,Ⅰ급、Ⅱ급、Ⅲ급화Ⅳ급조분별위24례、32례、23례、21례.측량좌심방직경(LAD)、좌심실수축말경(LVESD)、좌심실서장말경(LVEDD),이개량Simpson법측량좌심실사혈분수(LVEF).매련면역법측정혈장BNP. 결과 4조환자LVESD、LVEDD、LVEF、BNP화logBNP등지표비교,차이유통계학의의(F치분별위7.21、10.70、11.12、19.70、74.21,P＜0.05혹P＜0.01).혈장BNP농도여LVESD(r=0.27,P＜0.01)、LVEDD (r=0.37,P＜0.01)정정상관；여LVEF정부상관(r=-0.38,P＜0.01). 결론 급성심기경사노년환자적심공능하강,BNP가평개노년급성심기경사환자적심공능.
Objective To investigate the relationship between brain natriuretic peptide (BNP)and heart function in elderly patients with acute myocardial infarction.Methods All data were taken from the hospitalized cases with acute myocardial infarction from December 2008 to August 2010.100 patients aged from 60 to 97 were enrolled.The data were divided into 4 groups (group 1,24 cases; group 2,32 cases,group 3,23 cases; group 4,21 cases) respectively according to Killip's classification.Left ventricular function was measured by echocardiography.Plasma BNP was determined with enzyme immunoassay.Results Compared with non heart failure group and normal group,heart failure group had much higher plasma BNP concentrations.The plasma BNP level had positive correlation with left ventricular end diastolic diameter (r =0.27,P ＜ 0.01) and left ventricular end-diastolic dimension (r=0.37,P＜0.01),while,had a negative correlation with left ventricular ejection fraction (r =-0.38,P ＜ 0.01).Conclusions Plasma BNP level was significantly elevated which could evaluate the heart function in elderly patients with acute myocardial infarction.
