中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2014年
3期
261-263
,共3页
非那雄胺%良性前列腺增生%骨质疏松
非那雄胺%良性前列腺增生%骨質疏鬆
비나웅알%량성전렬선증생%골질소송
Finasteride%Benign prostatic hyperplasia%Osteoporosis
目的 分析非那雄胺对老年良性前列腺增生(BPH)患者骨密度的影响. 方法 回顾性分析我院120例老年BPH患者,根据是否服用非那雄胺分为两组,所有患者在随访前实施骨密度检查,随访观察12～15个月后再次实施骨密度检查,同时检测血清钙、肌酐、碱性磷酸酶的水平.结果 非那雄胺组与对照组在骨密度、血钙、肌酐及碱性磷酸酶方面差异无统计学意义(均P＞0.05). 结论 非那雄胺不会增加老年BPH患者骨质疏松的风险.
目的 分析非那雄胺對老年良性前列腺增生(BPH)患者骨密度的影響. 方法 迴顧性分析我院120例老年BPH患者,根據是否服用非那雄胺分為兩組,所有患者在隨訪前實施骨密度檢查,隨訪觀察12～15箇月後再次實施骨密度檢查,同時檢測血清鈣、肌酐、堿性燐痠酶的水平.結果 非那雄胺組與對照組在骨密度、血鈣、肌酐及堿性燐痠酶方麵差異無統計學意義(均P＞0.05). 結論 非那雄胺不會增加老年BPH患者骨質疏鬆的風險.
목적 분석비나웅알대노년량성전렬선증생(BPH)환자골밀도적영향. 방법 회고성분석아원120례노년BPH환자,근거시부복용비나웅알분위량조,소유환자재수방전실시골밀도검사,수방관찰12～15개월후재차실시골밀도검사,동시검측혈청개、기항、감성린산매적수평.결과 비나웅알조여대조조재골밀도、혈개、기항급감성린산매방면차이무통계학의의(균P＞0.05). 결론 비나웅알불회증가노년BPH환자골질소송적풍험.
Objective To retrospectively investigate the effect of finasteride on bone mineral density in elderly patients with benign prostatic hyperplasia (BPH).Methods 120 elderly patients with BPH were retrospective studied in our hospital,and grouped into the finasteride group and the control group according to taking finasteride or not.Bone mineral density in all patients was measured by dual energy X-ray absorptiometry at baseline and 12-15 months after follow-up,and peripheral blood was collected for measuring serum biochemical indicators including calcium,phosphorus,creatinine and alkaline phosphatase (ALP).Results There were no significant differences in indexes of bone mineral density,serum calcium,phosphorus,creatinine and ALP between the finasteride group and the control group.Conclusions Finasteride may not increase the risk of osteoporosis in elderly patients with BPH.
