中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2014年
5期
488-491
,共4页
任卫英%李丽%赵蓉雅%朱蕾
任衛英%李麗%趙蓉雅%硃蕾
임위영%리려%조용아%주뢰
呼吸功能试验%健康状况
呼吸功能試驗%健康狀況
호흡공능시험%건강상황
Respiratory function tests%Health status
目的 分析上海地区中老年人群的肺功能参数,探讨其变化规律. 方法 选取2009年6月至2011年9月期间肺功能测定结果正常且不吸烟的健康体检者,其中年龄超过44岁者298例,分为老年前期组(45～59岁)、低龄老年组(60～69岁)和中高龄老年组(≥70岁);19～44岁的227例作为青年组.收集13项肺功能参数:肺活量、用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、第一秒率(FEV1/FVC)、功能残气量(FRC)、峰流量、用力肺容积25％时的最大呼气流速(FEF25)、用力肺容积50％时的最大呼气流速(FEF50)、肺总量、残气容积、残气容积/肺总量、肺一氧化碳弥散量(DLCO)和每升肺泡容积的一氧化碳弥散量(KCO). 结果 与青年人比较,中老年人肺活量、FVC、FEV1、峰流量、肺总量,DLCO和KCO皆下降;残气容积、残气容积/肺总量皆升高[男性组(1.9±0.4)L比(1.6±0.3)L、(34.7±4.9)％比(26.4±4.3)％,P＜0.01;女性组(1.5±0.3)L比(1.3±0.3)L、(36.1±5.3)％比(30.3±5.5)％,P＜0.01].随着年龄的增长,残气容积呈进一步升高趋势,但差异无统计学意义(P＞0.05),FRC基本无变化(P＞0.05).中老年人FEV1/FVC较青年人降低[男性组(80.7±4.3)％比(84.2±5.6)％,P＜0.01;女性组(82.5±5.5)％比(86.4±4.8)％,P＜0.01],但中老年人不同年龄组间差异无统计学意义(P＞0.05),其中年龄≥70岁的男性FEV1/FVC为(80.2±4.5)％,女性为(81.8±5.6)％. 结论 中老年人肺通气功能和弥散功能均随着年龄的增大而逐渐下降,残气量呈缓慢的升高趋势,但FRC基本稳定,FEV1/FVC的下降趋势明显减缓.
目的 分析上海地區中老年人群的肺功能參數,探討其變化規律. 方法 選取2009年6月至2011年9月期間肺功能測定結果正常且不吸煙的健康體檢者,其中年齡超過44歲者298例,分為老年前期組(45～59歲)、低齡老年組(60～69歲)和中高齡老年組(≥70歲);19～44歲的227例作為青年組.收集13項肺功能參數:肺活量、用力肺活量(FVC)、第一秒用力呼氣容積(FEV1)、第一秒率(FEV1/FVC)、功能殘氣量(FRC)、峰流量、用力肺容積25％時的最大呼氣流速(FEF25)、用力肺容積50％時的最大呼氣流速(FEF50)、肺總量、殘氣容積、殘氣容積/肺總量、肺一氧化碳瀰散量(DLCO)和每升肺泡容積的一氧化碳瀰散量(KCO). 結果 與青年人比較,中老年人肺活量、FVC、FEV1、峰流量、肺總量,DLCO和KCO皆下降;殘氣容積、殘氣容積/肺總量皆升高[男性組(1.9±0.4)L比(1.6±0.3)L、(34.7±4.9)％比(26.4±4.3)％,P＜0.01;女性組(1.5±0.3)L比(1.3±0.3)L、(36.1±5.3)％比(30.3±5.5)％,P＜0.01].隨著年齡的增長,殘氣容積呈進一步升高趨勢,但差異無統計學意義(P＞0.05),FRC基本無變化(P＞0.05).中老年人FEV1/FVC較青年人降低[男性組(80.7±4.3)％比(84.2±5.6)％,P＜0.01;女性組(82.5±5.5)％比(86.4±4.8)％,P＜0.01],但中老年人不同年齡組間差異無統計學意義(P＞0.05),其中年齡≥70歲的男性FEV1/FVC為(80.2±4.5)％,女性為(81.8±5.6)％. 結論 中老年人肺通氣功能和瀰散功能均隨著年齡的增大而逐漸下降,殘氣量呈緩慢的升高趨勢,但FRC基本穩定,FEV1/FVC的下降趨勢明顯減緩.
목적 분석상해지구중노년인군적폐공능삼수,탐토기변화규률. 방법 선취2009년6월지2011년9월기간폐공능측정결과정상차불흡연적건강체검자,기중년령초과44세자298례,분위노년전기조(45～59세)、저령노년조(60～69세)화중고령노년조(≥70세);19～44세적227례작위청년조.수집13항폐공능삼수:폐활량、용력폐활량(FVC)、제일초용력호기용적(FEV1)、제일초솔(FEV1/FVC)、공능잔기량(FRC)、봉류량、용력폐용적25％시적최대호기류속(FEF25)、용력폐용적50％시적최대호기류속(FEF50)、폐총량、잔기용적、잔기용적/폐총량、폐일양화탄미산량(DLCO)화매승폐포용적적일양화탄미산량(KCO). 결과 여청년인비교,중노년인폐활량、FVC、FEV1、봉류량、폐총량,DLCO화KCO개하강;잔기용적、잔기용적/폐총량개승고[남성조(1.9±0.4)L비(1.6±0.3)L、(34.7±4.9)％비(26.4±4.3)％,P＜0.01;녀성조(1.5±0.3)L비(1.3±0.3)L、(36.1±5.3)％비(30.3±5.5)％,P＜0.01].수착년령적증장,잔기용적정진일보승고추세,단차이무통계학의의(P＞0.05),FRC기본무변화(P＞0.05).중노년인FEV1/FVC교청년인강저[남성조(80.7±4.3)％비(84.2±5.6)％,P＜0.01;녀성조(82.5±5.5)％비(86.4±4.8)％,P＜0.01],단중노년인불동년령조간차이무통계학의의(P＞0.05),기중년령≥70세적남성FEV1/FVC위(80.2±4.5)％,녀성위(81.8±5.6)％. 결론 중노년인폐통기공능화미산공능균수착년령적증대이축점하강,잔기량정완만적승고추세,단FRC기본은정,FEV1/FVC적하강추세명현감완.
Objective To observe the changes of pulmonary function parameters in healthy middle-aged and elderly people in Shanghai.Methods A total of 298 subjects aged 45 years and over with normal pulmonary function and no smoking history were selected among subjects who underwent routine physical examination from Jun 2009 to Sep 2011.The subjects were divided into three groups:45-59 years,60-69 years,and ≥70 years.The tested pulmonary function included 13 parameters:vital capacity (VC),residual volume (RV),functional residual capacity (FRC),total lung capacity (TLC),RV/TLC,forced vital capacity (FVC),forced expiratory volume in one second (FEV1),FEV1/FVC,peak expiratory flow (PEF),forced expiratory flow at 25 ％ of FVC exhaled (FEF25),forced expiratory flow at 50％ of FVC exhaled (FEF50),diffusion capacity of the lung for carbon monoxide (DLCO),and specific diffusion capacity of CO (KCO).Results Compared with the young adults,7 pulmonary function parameters including VC,FVC,FEV1,PEF,TLC,DLCO and KCO were declined significantly in healthy middle aged and elderly people Compared with the young adults,pulmonary function parameters including RV and RV/TLC were increased [male (1.9 ±0.4)Lvs.(1.6±0.3)L,(34.7±4.9)％ vs.(26.4±4.3)％,P＜0.01;female (1.5±0.3)L vs.(1.3±0.3)L,(36.1±5.3)％ vs.(30.3±5.5)％,P＜0.01].Although RVincreased with aging in middle-aged and elderly people,but there was no statistical significance (P＞0.05).FRC didn't change obviously.FEV1/FVC was lower in old people than in young people[male (80.7±4.3)％ vs.(84.2±5.6)％,P ＜0.01;female (82.5± 5.5) ％ vs.(86.4±4.8)％,P＜0.01],but the difference between 3 groups of middle-aged and the elderly was not significant.The FEV1/FVC of men and women aged 70 and more were (80.2±4.5)％ and (81.8±5.6)％,respectively.Conclusions Both ventilation function and diffusion function of healthy elderly people are decreased with ageing,RV is increased and FRC is steady,and the declining tendency of FEV1/FVC obviously slows down with aging in middle aged and elderly people.
