CAJ | 학술논문

目的比较蒙特利尔认知评估量表(MoCA)和简易精神状态检查(MMSE)筛查老年颅脑创伤患者认知障碍的能力. 方法对常州市第一人民医院神经外科收治的40例老年颅脑创伤患者和40例健康对照组进行MoCA量表和MMSE量表的评价.绘制受试者工作曲线(ROC),比较MoCA量表和MMSE量表的筛查能力. 结果老年颅脑创伤组MoCA量表各子项目及总分均低于健康对照组(P＜0.05);MMSE量表中定向力、计算力、记忆及总分低于健康对照组(P＜0.05),而瞬时记忆、语言与健康对照组比较差异无统计学意义(P＞0.05).MoCA、MMSE量表在筛查老年颅脑创伤患者认知障碍时曲线下面积(AUC)比较,MoCA (0.92±0.03)＞MMSE(0.74±0.06),差异有统计学意义(Z=2.460,P＜0.01).利用ROC曲线分析发现,在筛查老年颅脑创伤患者认知障碍时,MMSE的最佳截断值为27.5,MoCA的最佳截断值为24.5. 结论老年颅脑创伤患者认知功能下降;MoCA量表在筛查老年颅脑创伤患者认知障碍时优于MMSE量表.
목적 비교몽특리이인지평고량표(MoCA)화간역정신상태검사(MMSE)사사노년로뇌창상환자인지장애적능력. 방법 대상주시제일인민의원신경외과수치적40례노년로뇌창상환자화40례건강대조조진행MoCA량표화MMSE량표적평개.회제수시자공작곡선(ROC),비교MoCA량표화MMSE량표적사사능력. 결과 노년로뇌창상조MoCA량표각자항목급총분균저우건강대조조(P＜0.05);MMSE량표중정향력、계산력、기억급총분저우건강대조조(P＜0.05),이순시기억、어언여건강대조조비교차이무통계학의의(P＞0.05).MoCA、MMSE량표재사사노년로뇌창상환자인지장애시곡선하면적(AUC)비교,MoCA (0.92±0.03)＞MMSE(0.74±0.06),차이유통계학의의(Z=2.460,P＜0.01).이용ROC곡선분석발현,재사사노년로뇌창상환자인지장애시,MMSE적최가절단치위27.5,MoCA적최가절단치위24.5. 결론 노년로뇌창상환자인지공능하강;MoCA량표재사사노년로뇌창상환자인지장애시우우MMSE량표.
Objective To compare the validity of Montreal cognitive assessment (MoCA) versus mini-mental state examination (MMSE) in screening cognition impairment in elderly patients with cranio-cerebral trauma.Methods Cognitive function in 40 elderly patients with cranio-cerebral trauma and 40 healthy elderly individuals were assessed by MoCA and MMSE.Receiver operating characteristic (ROC) curve analysis were performed to determine the optimal sensitivity and specificity of MoCA and MMSE.Results The total score and all the sub-test scores of MoCA were much lower in cranio-cerebral trauma patients than in the control group (all P＜0.05).The total score and orientation,calculation,recall,language sub scores of MMSE were significantly decreased in the elderly patients with cranio-cerebral trauma as compared with those in the controls (P＜0.05),while there were no significant differences in the immediate memory and language scores between the two groups (both P＞0.05).The area under the receiver operating characteristic curve showed that MoCA (0.92±0.03) ＞ MMSE (0.74±0.06) (Z=2.460,P＜0.01).When screening the cognition impairment in elderly patients with cranio cerebral trauma,the best cut-off scores of MoCA and MMSE were 24.5 and 27.5 respectively.Conclusions Cognition impairment is decreased in elderly patients with cranio cerebral trauma.The MoCA is superior to the MMSE as a screening instrument in detecting cognition impairment in elderly patients with cranio-cerebral trauma.