CAJ | 학술논문

目的探讨心率变异性时域指标在器质性心脏病患者中对室性心律失常发生的预测价值及其相关性分析. 方法对2012年3月至2013年10月来我院行动态心电图的300例患者的24 h动态心电图的心率变异性时域指标R-R间期的标准差(SDNN)、频域指标交感与迷走比值和心律失常数据进行回顾性分析. 结果器质性心脏病患者SDNN＜100 ms时室性心律失常发生率较无器质性心脏病SDNN＞ 100 ms者增高,为39.5％(45/114)比4.1％(3/74),差异有统计学意义(P＜0.01).器质性心脏病伴室性心律失常患者交感神经与迷走神经张力比值较无室性心律失常、无器质性心脏病者增高(19.9±2.3比10.1±1.7)(P＜0.01).时域指标SDNN与频域指标交感神经与迷走神经张力比值变化呈负相关(r=-0.819,P＜0.01). 结论 SDNN＜100 ms、交感神经与迷走神经张力比值增高可作为器质性心脏病患者发生室性心律失常的预测指标.
목적 탐토심솔변이성시역지표재기질성심장병환자중대실성심률실상발생적예측개치급기상관성분석. 방법 대2012년3월지2013년10월래아원행동태심전도적300례환자적24 h동태심전도적심솔변이성시역지표R-R간기적표준차(SDNN)、빈역지표교감여미주비치화심률실상수거진행회고성분석. 결과 기질성심장병환자SDNN＜100 ms시실성심률실상발생솔교무기질성심장병SDNN＞ 100 ms자증고,위39.5％(45/114)비4.1％(3/74),차이유통계학의의(P＜0.01).기질성심장병반실성심률실상환자교감신경여미주신경장력비치교무실성심률실상、무기질성심장병자증고(19.9±2.3비10.1±1.7)(P＜0.01).시역지표SDNN여빈역지표교감신경여미주신경장력비치변화정부상관(r=-0.819,P＜0.01). 결론 SDNN＜100 ms、교감신경여미주신경장력비치증고가작위기질성심장병환자발생실성심률실상적예측지표.
Objective To investigate the predictive value of heart rate variability to,and its correlation with ventricular arrhythmias in patients with structural heart disease.Methods 24 hours ambulatory electrocardiogram monitoring was administered during March 2012 and October 2013,and standard deviation of the NN interval (SDNN) in the time-domain analysis and sympathetic/vagal ratio in the frequency domain analysis were collected and retrospectively analyzed in 300 patients.Results The incidence rate of ventricular arrhythmias was higher in patients with structural heart disease in SDNN ＜100 ms group than in control group [4.1％ (3/74) vs.39.5％ (45/114),P＜0.01].The sympathetic/vagal ratio was significantly higher in group with structural heart disease and ventricular arrhythmia than in control group(19.9 ±2.3 vs.10.1 ±1.7,P＜0.01)The time-domain index SDNN was negatively correlated with the frequency domain index (sympathetic/vagal ratio) (r=-0.819,P ＜0.01).Conclusions SDNN ＜100ms and the increased sympathetic/vagal ratio can be considered as the predictors of ventricular arrhythmias in patients with structural heart disease.