中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2012年
11期
1159-1162
,共4页
袁俊%刘于飞%李魁彪%周杰%谢朝军%蔡文锋%潘捷云%刘青连%肖晓玲%狄飚%刘建平%马晓薇%刘艳慧%杨智聪
袁俊%劉于飛%李魁彪%週傑%謝朝軍%蔡文鋒%潘捷雲%劉青連%肖曉玲%狄飚%劉建平%馬曉薇%劉豔慧%楊智聰
원준%류우비%리괴표%주걸%사조군%채문봉%반첩운%류청련%초효령%적표%류건평%마효미%류염혜%양지총
禽流感%流行病学调查%感染来源
禽流感%流行病學調查%感染來源
금류감%류행병학조사%감염래원
Avian influenza%Epidemiology investigation%Infection sources
目的 明确1例人禽流感H5N1确诊病例的感染来源.方法 通过现场流行病学调查、密切接触者医学观察、高危从业人员症状监测、实验室检测和溯源调查等方法,判断感染来源.结果 2012年5月17-19日该患儿随母在广州A市场购买活鸭,现场经历屠宰过程.23、24日发病后在当地医院就诊,诊断为呼吸道感染；26日抵香港后诊断为人禽流感病例.23名密切接触者和34名市场禽类销售屠宰从业人员未出现流感样症状.患儿住家附近B市场2名禽类销售人员H9型血清抗体阳性,阳性率为6.06％(2/33).A、B两市场砧板、禽笼等环境标本H5、H9型阳性率分别为9.8％(5/51)和2.0％(1/51).B市场一份砧板H5型阳性标本与患儿标本同属2.3.2.1分支.B市场阳性档口的进货来源与A市场一致.结论 该禽流感病例的感染来源为广州市肉菜市场禽类销售档口.
目的 明確1例人禽流感H5N1確診病例的感染來源.方法 通過現場流行病學調查、密切接觸者醫學觀察、高危從業人員癥狀鑑測、實驗室檢測和溯源調查等方法,判斷感染來源.結果 2012年5月17-19日該患兒隨母在廣州A市場購買活鴨,現場經歷屠宰過程.23、24日髮病後在噹地醫院就診,診斷為呼吸道感染；26日牴香港後診斷為人禽流感病例.23名密切接觸者和34名市場禽類銷售屠宰從業人員未齣現流感樣癥狀.患兒住傢附近B市場2名禽類銷售人員H9型血清抗體暘性,暘性率為6.06％(2/33).A、B兩市場砧闆、禽籠等環境標本H5、H9型暘性率分彆為9.8％(5/51)和2.0％(1/51).B市場一份砧闆H5型暘性標本與患兒標本同屬2.3.2.1分支.B市場暘性檔口的進貨來源與A市場一緻.結論 該禽流感病例的感染來源為廣州市肉菜市場禽類銷售檔口.
목적 명학1례인금류감H5N1학진병례적감염래원.방법 통과현장류행병학조사、밀절접촉자의학관찰、고위종업인원증상감측、실험실검측화소원조사등방법,판단감염래원.결과 2012년5월17-19일해환인수모재엄주A시장구매활압,현장경력도재과정.23、24일발병후재당지의원취진,진단위호흡도감염；26일저향항후진단위인금류감병례.23명밀절접촉자화34명시장금류소수도재종업인원미출현류감양증상.환인주가부근B시장2명금류소수인원H9형혈청항체양성,양성솔위6.06％(2/33).A、B량시장침판、금롱등배경표본H5、H9형양성솔분별위9.8％(5/51)화2.0％(1/51).B시장일빈침판H5형양성표본여환인표본동속2.3.2.1분지.B시장양성당구적진화래원여A시장일치.결론 해금류감병례적감염래원위엄주시육채시장금류소수당구.
Objective We conducted an epidemiologic investigation to determine the source of infection on an avian influenza (H5N1) case who returned from Guangzhou,in Hong Kong.Methods Data related to epidemiologic investigation,medical observation on close contacts,Syndromic Surveillance on poultry salesmen,emergency monitoring,detection of the samples,source tracing on potential Avian influenza virus (H5,H7,H9) infected people,situation on environment pollution by avian influenza virus in the markets etc.were gathered.The determination of infection source was through comparing the different genes between the case and positive environmental samples.Results The infected case witnessed the procedure of how a live duck was killed,in market A in Guangzhou during May 17th to 19th.The case was diagnosed as respiratory tract infection in 2 Third-grade-Class A hospitals in Guangzhou on May 23th and 24th.The diagnosis was made as Avian influenza cases on May 26th after going back to Hong Kong.23 close contacts and 34 markets poultry salesmen did not show any ILI related symptoms.However,2 poultry salesmen from the markets nearby the place where the Avian influenza case stayed,were detected having positive H9 avian influenza antibody,with the H9 positive rate as 6.06％ (2/33).Among the environmental samples in the 2 markets nearby home of the patient,chopping block was found to have carried H5,with positive rate as 9.8％(5/51) while poultry cage was found to carry H9,with the positive rate as 2.0％(1/51).A H5 positive sample was found with clade 2.3.2.1,same to the case,from a chopping block at the market B where the sources of poultry was the same as market A.Conclusion The source of infection seemed to come from the markets in Guangzhou,that calling for the strengthening of poultry market management,for avian influenza prevention.History related to contact of poultry should be gathered when a diagnosis of respiratory tract infection was made.Timely sampling and testing should be made to improve the sensitivity of diagnosis.
