中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
4期
331-335
,共5页
王旭英%董凤鸣%金明好%潘小川
王旭英%董鳳鳴%金明好%潘小川
왕욱영%동봉명%금명호%반소천
大气可吸入颗粒物%脑血管疾病%病例交叉研究
大氣可吸入顆粒物%腦血管疾病%病例交扠研究
대기가흡입과립물%뇌혈관질병%병례교차연구
Ambient inhalable particulate matter%Cerebrovascular diseases%Case-crossover study
目的 分析北京市可吸入颗粒物(PM10)浓度与暴露人群脑血管疾病死亡的相关性,探索PM10对人群脑血管疾病死亡的影响.方法 收集2004-2008年北京市某城区气象因素、大气污染物(PM10、SO2、NO2)水平以及人群脑血管疾病死亡数据,采用双向对称性病例交叉设计和条件logistic回归模型,分析大气中PM10水平与脑血管疾病之间的关系.结果 调整气象因素(日平均气温和日平均相对湿度)后,单污染物模型PM10的滞后效应不明显.调整SO2、NO2和SO2+NO2后的多污染物模型,PM10对人群脑血管疾病的效应OR值比单污染物模型大且差异有统计学意义(P＜0.05).分层分析显示,大气PM10浓度对女性、≥65岁的脑血管疾病和冬季脑血管疾病病例效应差异有统计学意义(P＜0.05),而对男性和≥65岁的脑血管疾病病例效应无统计学意义(P＞0.05).结论 调整其他大气污染物和气象因素后,PM10浓度与脑血管疾病死亡呈正相关.PM10浓度升高会导致女性、≥65岁和冬季脑血管疾病死亡增加.
目的 分析北京市可吸入顆粒物(PM10)濃度與暴露人群腦血管疾病死亡的相關性,探索PM10對人群腦血管疾病死亡的影響.方法 收集2004-2008年北京市某城區氣象因素、大氣汙染物(PM10、SO2、NO2)水平以及人群腦血管疾病死亡數據,採用雙嚮對稱性病例交扠設計和條件logistic迴歸模型,分析大氣中PM10水平與腦血管疾病之間的關繫.結果 調整氣象因素(日平均氣溫和日平均相對濕度)後,單汙染物模型PM10的滯後效應不明顯.調整SO2、NO2和SO2+NO2後的多汙染物模型,PM10對人群腦血管疾病的效應OR值比單汙染物模型大且差異有統計學意義(P＜0.05).分層分析顯示,大氣PM10濃度對女性、≥65歲的腦血管疾病和鼕季腦血管疾病病例效應差異有統計學意義(P＜0.05),而對男性和≥65歲的腦血管疾病病例效應無統計學意義(P＞0.05).結論 調整其他大氣汙染物和氣象因素後,PM10濃度與腦血管疾病死亡呈正相關.PM10濃度升高會導緻女性、≥65歲和鼕季腦血管疾病死亡增加.
목적 분석북경시가흡입과립물(PM10)농도여폭로인군뇌혈관질병사망적상관성,탐색PM10대인군뇌혈관질병사망적영향.방법 수집2004-2008년북경시모성구기상인소、대기오염물(PM10、SO2、NO2)수평이급인군뇌혈관질병사망수거,채용쌍향대칭성병례교차설계화조건logistic회귀모형,분석대기중PM10수평여뇌혈관질병지간적관계.결과 조정기상인소(일평균기온화일평균상대습도)후,단오염물모형PM10적체후효응불명현.조정SO2、NO2화SO2+NO2후적다오염물모형,PM10대인군뇌혈관질병적효응OR치비단오염물모형대차차이유통계학의의(P＜0.05).분층분석현시,대기PM10농도대녀성、≥65세적뇌혈관질병화동계뇌혈관질병병례효응차이유통계학의의(P＜0.05),이대남성화≥65세적뇌혈관질병병례효응무통계학의의(P＞0.05).결론 조정기타대기오염물화기상인소후,PM10농도여뇌혈관질병사망정정상관.PM10농도승고회도치녀성、≥65세화동계뇌혈관질병사망증가.
Objective To analyze the association between the concentration of ambient inhalable particulate matter (PM10) and population mortality for cerebrovascular diseases and to explore the impact of PM10 on cerebrovascular diseases.Methods Data including meteorological factors,air pollutants (NO2,SO2 and PM10) and cerebrovascular disease mortality in one district of Beijing from 2004 to 2008 were collected and both symmetric bidirectional case-crossover design and conditional logistic regression model were used to analyze the associations among them.Results After adjusting the influence of meteorological factors as daily average temperature and relative humidity,the single pollutant model showed that there was no significant lag effect.In the multipollutant model,the effect of the every 105.43 μg/m3 increase of ambient PM10 had a larger impact on the daily death of the cerebrovascular diseases with statistically significant difference (P＜0.05).The effect of ambient PM10 pollution on daily death of cerebrovascular diseases was significant for females,65 year-olds and in winter season.Conclusion Our data showed that elevated levels of ambient PM10was positively associated with the increase of cerebrovascular disease mortality.The elevated levels of ambient PM10 could lead to thc increase of the daily mortality on cerebrovascular diseases for females,elderly who were 65 or older and in winter seasons.
