中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
4期
389-392
,共4页
周宪君%邱洪斌%徐辉%祝丽玲
週憲君%邱洪斌%徐輝%祝麗玲
주헌군%구홍빈%서휘%축려령
痉挛型脑瘫%危险因素%Logistic回归分析
痙攣型腦癱%危險因素%Logistic迴歸分析
경련형뇌탄%위험인소%Logistic회귀분석
Spastic type of cerebral palsy%Risk factors%Logistic regression analysis
目的 筛查痉挛型脑性瘫痪(脑瘫)的危险因素.方法 采用1∶2病例对照研究,选择2007年12月至2009年5月在黑龙江省小儿脑性瘫痪防治疗育中心就诊的脑瘫患儿145例为病例组,同时按照年龄±3个月及性别、民族相同原则进行匹配,选择同期在佳木斯大学附属第一医院就诊并排除中枢神经系统疾病的290名儿童作为对照组,通过问卷调查获取相关信息,采用条件logistic回归分析筛查危险因素.结果 单因素条件logistic回归分析共39项因素有统计学意义,多因素logistic回归分析有11项因素与脑瘫发生有关,分别是出生体重过低(＜2.5 kg)或过高(＞4.0 kg)、母亲大学及以上学历、新生儿出生时肌张力高、皮色青紫、孕期服用解热镇痛药、孕期经历重大事件影响、居室周围环境有污染、新生儿出生时患有颅内出血和出生窒息、宫内窘迫.结论 新生儿因素与脑瘫发生关系密切,普及孕产期保健知识,加强新生儿管理是减少脑瘫发生的重要措施.
目的 篩查痙攣型腦性癱瘓(腦癱)的危險因素.方法 採用1∶2病例對照研究,選擇2007年12月至2009年5月在黑龍江省小兒腦性癱瘓防治療育中心就診的腦癱患兒145例為病例組,同時按照年齡±3箇月及性彆、民族相同原則進行匹配,選擇同期在佳木斯大學附屬第一醫院就診併排除中樞神經繫統疾病的290名兒童作為對照組,通過問捲調查穫取相關信息,採用條件logistic迴歸分析篩查危險因素.結果 單因素條件logistic迴歸分析共39項因素有統計學意義,多因素logistic迴歸分析有11項因素與腦癱髮生有關,分彆是齣生體重過低(＜2.5 kg)或過高(＞4.0 kg)、母親大學及以上學歷、新生兒齣生時肌張力高、皮色青紫、孕期服用解熱鎮痛藥、孕期經歷重大事件影響、居室週圍環境有汙染、新生兒齣生時患有顱內齣血和齣生窒息、宮內窘迫.結論 新生兒因素與腦癱髮生關繫密切,普及孕產期保健知識,加彊新生兒管理是減少腦癱髮生的重要措施.
목적 사사경련형뇌성탄탄(뇌탄)적위험인소.방법 채용1∶2병례대조연구,선택2007년12월지2009년5월재흑룡강성소인뇌성탄탄방치료육중심취진적뇌탄환인145례위병례조,동시안조년령±3개월급성별、민족상동원칙진행필배,선택동기재가목사대학부속제일의원취진병배제중추신경계통질병적290명인동작위대조조,통과문권조사획취상관신식,채용조건logistic회귀분석사사위험인소.결과 단인소조건logistic회귀분석공39항인소유통계학의의,다인소logistic회귀분석유11항인소여뇌탄발생유관,분별시출생체중과저(＜2.5 kg)혹과고(＞4.0 kg)、모친대학급이상학력、신생인출생시기장력고、피색청자、잉기복용해열진통약、잉기경력중대사건영향、거실주위배경유오염、신생인출생시환유로내출혈화출생질식、궁내군박.결론 신생인인소여뇌탄발생관계밀절,보급잉산기보건지식,가강신생인관리시감소뇌탄발생적중요조시.
Objective To study the risk factors related to spastic type of cerebral palsy through a screening program.Methods With a 1 ∶ 2 matched case-control study design,145 cases were selected from the Cerebral Palsy Treatment and Management Center in Heilongjiang Province from Dec.,2007 through May 2009.Another 290 cases of children as control group were chosen from the First Affiliated Hospital of Jiamusi University,in the same period.Controls were excluded the central nervous system diseases,matching with cases at the age differences no more than 3 months,with same sex and ethnicity.Questionnaire survey was used to access relevant information,while logistic regression analysis was used to screen the risk factors.Results Data from Single factor logistic regression analysis notified 39 items as statistically significant factors.Through multivariate logistic regression analysis,11 factors in all the cerebral palsy cases,and incidence of cerebral palsy risk factors related to low or high birth weight were discovered as follows:mother with college degree,newborns with high muscle tone,skin color as purple,taking antipyretic analgesics drugs during pregnancy,experience significant events during pregnancy,situation of environment pollution around the house,having intracranial hemorrhage and birth asphyxia,fetal distress during pregnancy or neonatal stage etc.Conclusion Pre/Nconatal factors were closely related to cerebral palsy,suggesting that health care knowledge be popularized and related management be strengthened,to reduce the cerebral palsy incidence in the newborns.
