中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
7期
696-700
,共5页
郭启高%赵辉%张业武%王晓风%贺琴%刘韫宁%周脉耕
郭啟高%趙輝%張業武%王曉風%賀琴%劉韞寧%週脈耕
곽계고%조휘%장업무%왕효풍%하금%류운저%주맥경
肝癌%水污染%死亡率%空间分析
肝癌%水汙染%死亡率%空間分析
간암%수오염%사망솔%공간분석
Liver carcinoma%Drink water pollution%Mortality%Spatial analysis
目的 观察安徽省灵璧县30年肝癌死亡水平及其变化,并对2005-2010年肝癌死亡情况进行空间分析.方法 使用1973-1975年和2005-2010年灵璧县死因数据,通过与全国和该县历史水平对比,观察灵璧县肝癌死亡水平及其变化.使用Poisson分布模型、BYM模型以及热点探测等方法,计算2005-2010年灵璧县各村肝癌标化死亡比(SMR)和RR值,并确定肝癌死亡的高聚集区.结果 30年间灵璧县肝癌SMR上升223.7%,由1973-1975年低于全国水平的22.7%,上升至2005-2010年的74.1%,高出全国水平,并呈现沿奎濉河附近村庄较高水平分布的特点.聚集性分析发现,在5300m处存在有意义的显著空间正自相关.灵璧县肝癌死亡具有一个非常明显的热点区域,即分布在奎濉河沿岸尤其是在老濉河和新濉河分叉处的地区.结论 30年间灵璧县肝癌死亡率明显上升,高发区域主要分布在奎濉河附近村落,提示可能存在促进肝癌发生的相同因素.
目的 觀察安徽省靈璧縣30年肝癌死亡水平及其變化,併對2005-2010年肝癌死亡情況進行空間分析.方法 使用1973-1975年和2005-2010年靈璧縣死因數據,通過與全國和該縣歷史水平對比,觀察靈璧縣肝癌死亡水平及其變化.使用Poisson分佈模型、BYM模型以及熱點探測等方法,計算2005-2010年靈璧縣各村肝癌標化死亡比(SMR)和RR值,併確定肝癌死亡的高聚集區.結果 30年間靈璧縣肝癌SMR上升223.7%,由1973-1975年低于全國水平的22.7%,上升至2005-2010年的74.1%,高齣全國水平,併呈現沿奎濉河附近村莊較高水平分佈的特點.聚集性分析髮現,在5300m處存在有意義的顯著空間正自相關.靈璧縣肝癌死亡具有一箇非常明顯的熱點區域,即分佈在奎濉河沿岸尤其是在老濉河和新濉河分扠處的地區.結論 30年間靈璧縣肝癌死亡率明顯上升,高髮區域主要分佈在奎濉河附近村落,提示可能存在促進肝癌髮生的相同因素.
목적 관찰안휘성령벽현30년간암사망수평급기변화,병대2005-2010년간암사망정황진행공간분석.방법 사용1973-1975년화2005-2010년령벽현사인수거,통과여전국화해현역사수평대비,관찰령벽현간암사망수평급기변화.사용Poisson분포모형、BYM모형이급열점탐측등방법,계산2005-2010년령벽현각촌간암표화사망비(SMR)화RR치,병학정간암사망적고취집구.결과 30년간령벽현간암SMR상승223.7%,유1973-1975년저우전국수평적22.7%,상승지2005-2010년적74.1%,고출전국수평,병정현연규수하부근촌장교고수평분포적특점.취집성분석발현,재5300m처존재유의의적현저공간정자상관.령벽현간암사망구유일개비상명현적열점구역,즉분포재규수하연안우기시재로수하화신수하분차처적지구.결론 30년간령벽현간암사망솔명현상승,고발구역주요분포재규수하부근촌락,제시가능존재촉진간암발생적상동인소.
Objective To observe the mortality and its changes on liver cancer in the past 30 years as well as to describe the spatial distribution of liver cancer deaths between 2005 and 2010 in Lingbi,Anhui province.Methods Using the mortality data from 1973-1975 and from 2005 to 2010 in Lingbi to compare with the relative national and historical data,to observe the trend of rapid increase on liver cancer mortality in Lingbi.Using the Poisson model,BYM model and hotspot detection method,standardized mortality ratio (SMR),relative risk(RR) value of liver cancer deaths of each village were calculated and the clustering of high liver cancer deaths was identified.Results Through an increase of 223.7% on the SMR of liver cancer in the past 30 years,the standardized mortality of liver cancer in Lingbi had an increase of 74.1 percent than the national level in 2005-2010 but it was 22.7% lower than the country level in 1973-1975.The SMR and RR values and their P values were higher in the villages which were located along the Kuisui River.Data from the clustering analysis showed that there had been significantly positive autocorrelation at the altitude of 5300 meters,and a very obvious hot spot of liver cancer deaths existing along the Kuisui River,especially at the bifurcation of the old Sui River and new Sui River was observed.Conclusion There was an alarming increase of liver cancer mortality in the past 30 years in Lingbi.The high mortality area mainly covered the villages along the Kuisui River,suggesting that there were common risk factors for hepatocellular carcinoma in the population at risk.