中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
8期
826-831
,共6页
不孕率%系统综述%Meta分析
不孕率%繫統綜述%Meta分析
불잉솔%계통종술%Meta분석
Infertility rate%Systematic review%Meta-analysis
目的 运用循证分析方法估计中国育龄夫妇不孕率及其在不同地区和人群间的差别.方法 检索1980-2012年万方、维普、CNKI、PubMed数据库关于不孕率调查的文献,通过Meta分析合并不孕率,并通过Meta回归分析发现不孕率变异的来源.结果 纳入文献27篇.中国各地区总合并不孕率为5.7％(95％CI:5.3％～6.1％),新婚人群1年和2年合并不孕率分别为12.5％(95％CI:9.5％～15.4％)和6.6％(95％CI:4.9％ ～ 8.4％)；非新婚人群的1年和2年合并不孕率分别为6.4％(95％CI:4.2％～8.6％)和3.0％(95％CI:2.6％～3.3％).Meta回归分析发现各地区2年不孕率低于1年不孕率,经济水平低的地区不孕率高,文献的研究方法中历史性队列研究和前瞻性研究的不孕率较高.结论 由于各研究对于不孕率的界定不一致,导致各研究间不具有绝对的可比性.应重视各不孕率调查的可比性问题.
目的 運用循證分析方法估計中國育齡伕婦不孕率及其在不同地區和人群間的差彆.方法 檢索1980-2012年萬方、維普、CNKI、PubMed數據庫關于不孕率調查的文獻,通過Meta分析閤併不孕率,併通過Meta迴歸分析髮現不孕率變異的來源.結果 納入文獻27篇.中國各地區總閤併不孕率為5.7％(95％CI:5.3％～6.1％),新婚人群1年和2年閤併不孕率分彆為12.5％(95％CI:9.5％～15.4％)和6.6％(95％CI:4.9％ ～ 8.4％)；非新婚人群的1年和2年閤併不孕率分彆為6.4％(95％CI:4.2％～8.6％)和3.0％(95％CI:2.6％～3.3％).Meta迴歸分析髮現各地區2年不孕率低于1年不孕率,經濟水平低的地區不孕率高,文獻的研究方法中歷史性隊列研究和前瞻性研究的不孕率較高.結論 由于各研究對于不孕率的界定不一緻,導緻各研究間不具有絕對的可比性.應重視各不孕率調查的可比性問題.
목적 운용순증분석방법고계중국육령부부불잉솔급기재불동지구화인군간적차별.방법 검색1980-2012년만방、유보、CNKI、PubMed수거고관우불잉솔조사적문헌,통과Meta분석합병불잉솔,병통과Meta회귀분석발현불잉솔변이적래원.결과 납입문헌27편.중국각지구총합병불잉솔위5.7％(95％CI:5.3％～6.1％),신혼인군1년화2년합병불잉솔분별위12.5％(95％CI:9.5％～15.4％)화6.6％(95％CI:4.9％ ～ 8.4％)；비신혼인군적1년화2년합병불잉솔분별위6.4％(95％CI:4.2％～8.6％)화3.0％(95％CI:2.6％～3.3％).Meta회귀분석발현각지구2년불잉솔저우1년불잉솔,경제수평저적지구불잉솔고,문헌적연구방법중역사성대렬연구화전첨성연구적불잉솔교고.결론 유우각연구대우불잉솔적계정불일치,도치각연구간불구유절대적가비성.응중시각불잉솔조사적가비성문제.
Objective To estimate the infertility rates and to examine factors that contribute to the variations in infertility rates among studies.Methods Wanfang,CQVIP,CNKI,and PubMed Database were searched for infertility relevant population-based prevalence studies between 1980 and 2012.Meta-analysis and meta-regression were used to calculate the pooled size of effect and to identify the sources of variation.Results A total of 27 articles using data from regional surveys were included in the review.Results showed that the combined prevalence was 5.7％ (95％CI:5.3％-6.1％).Combined prevalence rates of 1-year and 2-year infertility in newly married couples were 12.5％ (95％CI:9.5％-15.4％) and 6.6％ (95％CI:4.9％-8.4％),respectively,while were respectively 6.4％ (95％CI:4.2％-8.6％) and 3.0％ (95％CI:2.6％-3.3％),in women of reproductive age.Results from Meta-regression showed that the prevalence of 2-year infertility was lower than that of 1-year while infertility in regions was seen higher under the poor socioeconomic condition than in the better regions.Infertility in studies using cohort or prospective studies was seen to be higher than in other studies.Conclusion Owing to the inconsistency in determining the numerator and denominator that were used to calculate the prevalence of infertility as well as the inconsistency in criteria used to define the infertility,an agreed definition on infertility needs to be followed,in order to facilitate the comparison among studies.
