CAJ | 학술논문

目的探讨睡眠时间与脑梗死的关系.方法采用病例对照研究方法选择2011年12月至2012年12月哈尔滨医科大学第二附属医院1037例脑梗死住院患者作为病例组,以同期健康体检的1205名非脑血管病者作为对照组,采用统一的调查问卷.数据分析采用x2、u检验和多因素非条件logistic回归模型.结果以睡眠时间6～8h者为基准相比,调整年龄、性别、BMI、腰臀围比值、吸烟、饮酒、高血压、糖尿病、冠心病以及血脂指标后,睡眠时间＜6h者患脑梗死的风险增加(OR=2.81,95％CI:1.68～4.70);睡眠时间＞8h者与脑梗死无关联(OR=0.76,95％CI:0.48～1.20).按照性别分层后,睡眠时间＜6h与脑梗死的相关性仍然存在,且女性睡眠时间＜6h者脑梗死发生风险高于男性,OR值分别为5.58(95％CI:1.78～17.52)、2.00(95％CI:1.10 ～ 3.64).结论睡眠不足可能是脑梗死的危险因素.
목적 탐토수면시간여뇌경사적관계.방법 채용병례대조연구방법선택2011년12월지2012년12월합이빈의과대학제이부속의원1037례뇌경사주원환자작위병례조,이동기건강체검적1205명비뇌혈관병자작위대조조,채용통일적조사문권.수거분석채용x2、u검험화다인소비조건logistic회귀모형.결과 이수면시간6～8h자위기준상비,조정년령、성별、BMI、요둔위비치、흡연、음주、고혈압、당뇨병、관심병이급혈지지표후,수면시간＜6h자환뇌경사적풍험증가(OR=2.81,95％CI:1.68～4.70);수면시간＞8h자여뇌경사무관련(OR=0.76,95％CI:0.48～1.20).안조성별분층후,수면시간＜6h여뇌경사적상관성잉연존재,차녀성수면시간＜6h자뇌경사발생풍험고우남성,OR치분별위5.58(95％CI:1.78～17.52)、2.00(95％CI:1.10 ～ 3.64).결론 수면불족가능시뇌경사적위험인소.
Objective To explore the relationship between duration of sleeping and cerebral infarction.Methods A case-control study involved 1037 cerebral infarction patients admitted by the Second Affiliated Hospital of Harbin Medical University,December 2011-December 2012 as cases.Another 1205 adults free from cerebro-vascular diseases who had undergone physical examination in the hospital at the same period,were served as controls.All the subjects were interviewed with unified questionnaire.Chi-square test,u-test and multivariate logistic regression analysis were performed.Results After adjustment for potential confounding factors including age,sex,body mass index,wrist-hip ratio,smoking,alcohol intake,hypertension,diabetes mellitus,coronary artery disease and lipid parameters,data from the multivariate logistic regression analysis showed that the risk of cerebral infarction was greater in people who slept less than 6 hours per night than those who slept between 6 hours and 8 hours per night,with an odds ratio (95％ CI) as 2.81 (95％ CI:1.68-4.70).There was no significant association between factor as ‘sleeping longer than 8 hours/pre day' and cerebral infarction.Through the subgroup analysis,data showed that the association between ‘ shorter than 6 hour sleep/night' and cerebral infarction consistently exsited,across the categories of sex,and the degree of association was greater in women than in men,with the odds ratio as 5.58 (95％CI:1.78-17.52) and 2.00(95％CI:1.10-3.64) respectively.Conclusion Short sleeping duration might increase the risk of developing cerebral infarction.