CAJ | 학술논문

目的探讨盆底肌训练缓解女性膀胱过度活动症(OAB)患者症状及改善患者生活质量的疗效.方法采取前瞻性随机抽样的方法,于2012年1-8月在门诊选取女性OAB患者107例,实际完成研究者91例,盆底肌训练加健康教育结合托特罗定治疗46例(实验组),普通健康教育结合托特罗定治疗45例(对照组),干预3个月,分别于干预前及干预2周、1个月、3个月对两组患者膀胱过度活动症症状评分(OABSS)、盆底肌肌力牛津分级进行测评,干预后6个月随访,同时采用King生活质量量表在干预前及干预3、6个月时对患者生活质量进行测评.结果治疗前实验组盆底肌力、OABSS评分分别为(2.87±0.65)、(7.61±2.28)分,对照组分别为(2.80±0.55)、(7.44±2.41)分,组间比较差异均无统计学意义(P＞0.05).治疗前实验组King生活质量量表各维度得分与对照组比较差异均无统计学意义(P＞0.05).治疗1个月、3个月后实验组患者盆底肌力得分分别为(3.15±0.63)、(3.57±0.58)分,对照组为(2.89±0.57)、(3.09±0.67)分,组间比较差异有统计学意义(P＜0.05).治疗后6个月时实验组OABSS评分为(1.13±1.93)分,对照组为(2.47±2.18)分,组间比较差异有统计学意义(JP＜0.05).治疗3个月后King生活质量量表中排尿问题严重性、行为受限、运动受限、社交受限、症状严重程度得分,两组间比较差异有统计学意义(P＜0.05).干预6个月后,两组患者各维度得分与治疗前比较差异均有统计学意义(P＜0.05).结论长期的盆底肌训练结合药物治疗能有效缓解女性OAB症状,提高患者生活质量.
목적 탐토분저기훈련완해녀성방광과도활동증(OAB)환자증상급개선환자생활질량적료효.방법 채취전첨성수궤추양적방법,우2012년1-8월재문진선취녀성OAB환자107례,실제완성연구자91례,분저기훈련가건강교육결합탁특라정치료46례(실험조),보통건강교육결합탁특라정치료45례(대조조),간예3개월,분별우간예전급간예2주、1개월、3개월대량조환자방광과도활동증증상평분(OABSS)、분저기기력우진분급진행측평,간예후6개월수방,동시채용King생활질량량표재간예전급간예3、6개월시대환자생활질량진행측평.결과 치료전실험조분저기력、OABSS평분분별위(2.87±0.65)、(7.61±2.28)분,대조조분별위(2.80±0.55)、(7.44±2.41)분,조간비교차이균무통계학의의(P＞0.05).치료전실험조King생활질량량표각유도득분여대조조비교차이균무통계학의의(P＞0.05).치료1개월、3개월후실험조환자분저기력득분분별위(3.15±0.63)、(3.57±0.58)분,대조조위(2.89±0.57)、(3.09±0.67)분,조간비교차이유통계학의의(P＜0.05).치료후6개월시실험조OABSS평분위(1.13±1.93)분,대조조위(2.47±2.18)분,조간비교차이유통계학의의(JP＜0.05).치료3개월후King생활질량량표중배뇨문제엄중성、행위수한、운동수한、사교수한、증상엄중정도득분,량조간비교차이유통계학의의(P＜0.05).간예6개월후,량조환자각유도득분여치료전비교차이균유통계학의의(P＜0.05).결론 장기적분저기훈련결합약물치료능유효완해녀성OAB증상,제고환자생활질량.
Objective To elavluate the efficacy of pelvic floor muscle training (PFMT) on symptoms and quality of life in the treatment of female overactive bladder (OAB).Methods Ninety-one female patients with OAB completed the prospective study and were divided into 2 groups.The study group had PFMT combined with comprehensive health education and tolterodine (n =46),and the control group had comprehensive health education combined with tolterodine (n =45).OAB symptom score (OABSS),King's health questionnaire (KHQ) and modified Oxford scale (MOS) were evaluated at baseline,2 weeks,1 month and 3 months.The patients were followed up for 6 months.Results The MOS and OABSS score in study group before the treatment were 2.87±0.65 and 7.61 ±2.28,respectively,and in control group they were 2.80±0.55 and 7.44±2.41,respectively.There was no significant difference between the 2 grotps (P＞ 0.05).There was no significant difference in KHQ domains before the treatment between the 2 groups (P＞ 0.05).The MOS scores were 3.15±0.63 and 3.57±0.58 after treatment of 1 and 3 months in study group,which were significantly improved compared with the values of 2.89±0.57 and 3.09±0.67 in control group (P＜0.05).The OABSS score was 1.13± 1.93 in study group after treatment of 6 months,which was significantly improved compared with the values of 2.47±2.18 in control group (P＜0.05).The Incontinence impact,Role Limitations,Physical Limitations,Social Limitations and Symptom Severity in study group improved significantly compared with the values in control group after treatment of 3 months (P＜0.05).Domains of KHQ scores were totally significantly improved after treatment of 6 months in study group than in control group(P＜0.05).Conclusion Long term PFMT may play an important role in the treatment of OAB,and can also improve the quality of life of the patients.