中华泌尿外科杂志
中華泌尿外科雜誌
중화비뇨외과잡지
CHINESE JOURNAL OF UROLOGY
2014年
9期
672-675
,共4页
前列腺癌%前列腺切除%腹腔镜%碘125
前列腺癌%前列腺切除%腹腔鏡%碘125
전렬선암%전렬선절제%복강경%전125
Prostate cancer%Radical prostatectomy%Laparoscope%125I
目的 比较3种手术方式治疗局限性高危前列腺癌的疗效和并发症. 方法 回顾性分析2006年7月至2010年7月收治的102例局限性高危前列腺癌患者的临床资料,其中51例接受开放式根治性前列腺切除术(A组),年龄(63.7±7.9)岁,PSA(31.8±6.6)μg/L,Gleason评分(8.5±0.5)分,T2c期38例,T3a期13例;32例采用腹腔镜下根治性前列腺切除术(B组),年龄(64.4+8.3)岁,PSA为(29.9±5.2) μg/L,Gleason(8.7±0.4)分,T2c期21例,T3a期11例;19例采用125I粒子植入术(C组),年龄(61.4+7.4)岁,PSA(30.6±5.7) μg/L,Gleason(8.6±0.6)分,T2c期8例,T3a期11例.比较3组患者的手术时间、出血量、住院时间、引流时间、胃肠功能恢复时间、医疗费用、术后并发症发生情况以及术后1、3、5年的生存率和复发率. 结果 A、B、C组的手术时间分别为(232.6±38.4)、(186.3±31.4)、(35.4±14.6) min,术中出血量分别为(413.6±132.4)、(273.9±77.4)、(19.4±4.4) ml,住院时间分别为(20.9±3.7)、(15.6±2.2)、(6.4±2.6)d,引流时间分别为(8.3±1.8)、(7.5±0.9)、(3.2±0.8)d,术后胃肠功能恢复时间分别为(4.1±0.6)、(3.2±0.4)、(0.4±0.1)d,医疗费用分别为(2.3±0.4)、(3.2±0.3)、(4.5±0.3)万元,差异均有统计学意义(P＜0.05).3组患者的术后并发症发生情况以及术后1、3、5年生存率和复发率比较差异均无统计学意义(P＞0.05). 结论 与开放式和腹腔镜下根治性前列腺切除术比较,125I粒子植入术治疗局限性高危前列腺癌具有微创性、出血少、手术时间短、患者恢复快等优势,且对肠道功能有较好的保护作用.
目的 比較3種手術方式治療跼限性高危前列腺癌的療效和併髮癥. 方法 迴顧性分析2006年7月至2010年7月收治的102例跼限性高危前列腺癌患者的臨床資料,其中51例接受開放式根治性前列腺切除術(A組),年齡(63.7±7.9)歲,PSA(31.8±6.6)μg/L,Gleason評分(8.5±0.5)分,T2c期38例,T3a期13例;32例採用腹腔鏡下根治性前列腺切除術(B組),年齡(64.4+8.3)歲,PSA為(29.9±5.2) μg/L,Gleason(8.7±0.4)分,T2c期21例,T3a期11例;19例採用125I粒子植入術(C組),年齡(61.4+7.4)歲,PSA(30.6±5.7) μg/L,Gleason(8.6±0.6)分,T2c期8例,T3a期11例.比較3組患者的手術時間、齣血量、住院時間、引流時間、胃腸功能恢複時間、醫療費用、術後併髮癥髮生情況以及術後1、3、5年的生存率和複髮率. 結果 A、B、C組的手術時間分彆為(232.6±38.4)、(186.3±31.4)、(35.4±14.6) min,術中齣血量分彆為(413.6±132.4)、(273.9±77.4)、(19.4±4.4) ml,住院時間分彆為(20.9±3.7)、(15.6±2.2)、(6.4±2.6)d,引流時間分彆為(8.3±1.8)、(7.5±0.9)、(3.2±0.8)d,術後胃腸功能恢複時間分彆為(4.1±0.6)、(3.2±0.4)、(0.4±0.1)d,醫療費用分彆為(2.3±0.4)、(3.2±0.3)、(4.5±0.3)萬元,差異均有統計學意義(P＜0.05).3組患者的術後併髮癥髮生情況以及術後1、3、5年生存率和複髮率比較差異均無統計學意義(P＞0.05). 結論 與開放式和腹腔鏡下根治性前列腺切除術比較,125I粒子植入術治療跼限性高危前列腺癌具有微創性、齣血少、手術時間短、患者恢複快等優勢,且對腸道功能有較好的保護作用.
목적 비교3충수술방식치료국한성고위전렬선암적료효화병발증. 방법 회고성분석2006년7월지2010년7월수치적102례국한성고위전렬선암환자적림상자료,기중51례접수개방식근치성전렬선절제술(A조),년령(63.7±7.9)세,PSA(31.8±6.6)μg/L,Gleason평분(8.5±0.5)분,T2c기38례,T3a기13례;32례채용복강경하근치성전렬선절제술(B조),년령(64.4+8.3)세,PSA위(29.9±5.2) μg/L,Gleason(8.7±0.4)분,T2c기21례,T3a기11례;19례채용125I입자식입술(C조),년령(61.4+7.4)세,PSA(30.6±5.7) μg/L,Gleason(8.6±0.6)분,T2c기8례,T3a기11례.비교3조환자적수술시간、출혈량、주원시간、인류시간、위장공능회복시간、의료비용、술후병발증발생정황이급술후1、3、5년적생존솔화복발솔. 결과 A、B、C조적수술시간분별위(232.6±38.4)、(186.3±31.4)、(35.4±14.6) min,술중출혈량분별위(413.6±132.4)、(273.9±77.4)、(19.4±4.4) ml,주원시간분별위(20.9±3.7)、(15.6±2.2)、(6.4±2.6)d,인류시간분별위(8.3±1.8)、(7.5±0.9)、(3.2±0.8)d,술후위장공능회복시간분별위(4.1±0.6)、(3.2±0.4)、(0.4±0.1)d,의료비용분별위(2.3±0.4)、(3.2±0.3)、(4.5±0.3)만원,차이균유통계학의의(P＜0.05).3조환자적술후병발증발생정황이급술후1、3、5년생존솔화복발솔비교차이균무통계학의의(P＞0.05). 결론 여개방식화복강경하근치성전렬선절제술비교,125I입자식입술치료국한성고위전렬선암구유미창성、출혈소、수술시간단、환자회복쾌등우세,차대장도공능유교호적보호작용.
Objective To compare clinical efficacy and complications of three operation methods for treating the localized and high risk prostate cancer.Methods From July 2006 to July 2010,102 cases with localized and high risk prostate cancer were included in the study.Among them,51 cases received open radical prostatectomy (Group A).Their characters included aged (63.7±7.9),PSA (31.8±6.6) μg/L,Gleason scores (8.5±0.5).In this group,T2c stage was diagnosed in 38 cases and T3a stage in 13 cases.32 cases received laparoscopic radical prostatectomy(Group B).Their characters included aged (64.4± 8.3),PSA (29.9±5.2) μg/L,Glcason scores (8.7±0.4).In this group,T2c stage was diagnosed in 21 cases and T3a stage in 11 cases.19 cases received 125I implantation (Group C).Their characters included aged (61.4± 7.4),PSA (30.6±.5.7)μg/L,Gleason scores (8.6±0.6).T2v stage was found in 8 cases and T3a stage in 11 cases.Operation time,amount of bleeding,hospitalization time,drainage time,gastrointestinal function recovery time,medical expenses and survival and recurrence rate in 1 year,3 years,5 years were compared within those groups.Results Operation time in three group were (232.6±38.4) min,(186.3±31.4) min,(35.4±14.6) min,respectively.Amount of bleeding in three group were (413.6±132.4) ml,(273.9± 77.4) ml,(19.4±4.4) ml,respectively.Hospitalization time in three group were (20.9±3.7) d,(15.6± 2.2) d,(6.4±2.6) d respectively.Drainage time in three group were (8.3±1.8) d,(7.5±0.9) d,(3.2± 0.8) d,respectively.Gastrointestinal function recovery time in three group were (4.1 ±0.6) d,(3.2± 0.4) d,(0.4±0.1) d,respectively.Medical expenses in three group were (23±4) thousand yuan,(32±3) thousand yuan,(45t3) thousand yuan respectively.All those items exhibited the significantly statistical difference (P＜0.05).The survival and recurrence rates had no significant difference during the follow-up in three groups.Conciusions Compared to the open radical prostectomy and laparoscopic radical prostectomy,particle implantation for prostate cancer had advantages in minimally invasive,less bleeding,short operation time,fast recovery and protection for Intestinal function.
