中华泌尿外科杂志
中華泌尿外科雜誌
중화비뇨외과잡지
CHINESE JOURNAL OF UROLOGY
2014年
10期
731-733
,共3页
黄毅%阴雷%黄海%高轶%崔心刚%王军凯%叶剑青%徐丹枫
黃毅%陰雷%黃海%高軼%崔心剛%王軍凱%葉劍青%徐丹楓
황의%음뢰%황해%고질%최심강%왕군개%협검청%서단풍
癌,肾细胞%青年%保留肾单位手术%根治性肾切除术%预后
癌,腎細胞%青年%保留腎單位手術%根治性腎切除術%預後
암,신세포%청년%보류신단위수술%근치성신절제술%예후
Carcinoma,renal cell%Young%Nephron sparing surgery%Radical nephrectomy%Prognosis
目的 探讨20～40岁青年肾细胞癌患者的临床病理特点、治疗效果及预后影响因素.方法 回顾性分析2001年1月至2011年5月接受手术治疗的128例青年肾细胞癌患者的临床资料.男82例,女46例.就诊时无明显症状者94例(73.4％).肿瘤最大径≤4 cm 54例(42.2％),＞4～7 cm 57例(44.5％),＞7 cm 17例(13.3％).临床分期T1期111例(86.7％),T2期17例(13.3％). 结果 128例手术均获成功.肿瘤病理类型以肾透明细胞癌(83例,64.8％)为主,分级以高分化癌(121例,94.5％)为主.术后1年、5年肿瘤特异性生存率分别为100％和96％.Log-rank检验分析显示,Fuhrman细胞核分级、肿瘤病理类型及临床分期与预后密切相关(P＜0.05). 结论 青年肾细胞癌病理类型以高分化、透明细胞癌为主,手术治疗效果及总体预后良好.Fuhrman细胞核分级、肿瘤病理类型及临床分期是影响青年肾细胞癌患者预后的独立危险因素.
目的 探討20～40歲青年腎細胞癌患者的臨床病理特點、治療效果及預後影響因素.方法 迴顧性分析2001年1月至2011年5月接受手術治療的128例青年腎細胞癌患者的臨床資料.男82例,女46例.就診時無明顯癥狀者94例(73.4％).腫瘤最大徑≤4 cm 54例(42.2％),＞4～7 cm 57例(44.5％),＞7 cm 17例(13.3％).臨床分期T1期111例(86.7％),T2期17例(13.3％). 結果 128例手術均穫成功.腫瘤病理類型以腎透明細胞癌(83例,64.8％)為主,分級以高分化癌(121例,94.5％)為主.術後1年、5年腫瘤特異性生存率分彆為100％和96％.Log-rank檢驗分析顯示,Fuhrman細胞覈分級、腫瘤病理類型及臨床分期與預後密切相關(P＜0.05). 結論 青年腎細胞癌病理類型以高分化、透明細胞癌為主,手術治療效果及總體預後良好.Fuhrman細胞覈分級、腫瘤病理類型及臨床分期是影響青年腎細胞癌患者預後的獨立危險因素.
목적 탐토20～40세청년신세포암환자적림상병리특점、치료효과급예후영향인소.방법 회고성분석2001년1월지2011년5월접수수술치료적128례청년신세포암환자적림상자료.남82례,녀46례.취진시무명현증상자94례(73.4％).종류최대경≤4 cm 54례(42.2％),＞4～7 cm 57례(44.5％),＞7 cm 17례(13.3％).림상분기T1기111례(86.7％),T2기17례(13.3％). 결과 128례수술균획성공.종류병리류형이신투명세포암(83례,64.8％)위주,분급이고분화암(121례,94.5％)위주.술후1년、5년종류특이성생존솔분별위100％화96％.Log-rank검험분석현시,Fuhrman세포핵분급、종류병리류형급림상분기여예후밀절상관(P＜0.05). 결론 청년신세포암병리류형이고분화、투명세포암위주,수술치료효과급총체예후량호.Fuhrman세포핵분급、종류병리류형급림상분기시영향청년신세포암환자예후적독립위험인소.
Objective To analyze the clinical pathological characteristics and prognosis of renal cell carcinoma (RCC) in adults aged 20-40 years.Methods The data of 128 young RCC (aged 20-40 years) from January 2001 to May 2011 were retrospectively analyzed.There were 82 males and 46 females,and 94 cases (73.4％) were asymptomatic.The clinical stage was T1 in 111 cases (86.7％) and T2 in 17 cases (13.3％).Results Surgical treatment of 128 patients was successful.The most frequent histological type was renal clear cell carcinoma (64.8％),and differentiation of most tumor was good (94.5％).The cancer-specific survival rates at 1-and 5-year were 100％ and 96％,respectively.Independent prognostic factors were tumor differentiation,pathological types and tumor stage (P＜0.05).Conclusions Well differentiation is most common in adults aged 20-40 years with RCC and the patients have good prognosis.Tumor differentiation,pathological types,tumor stages are independent prognostic factors for survival.
