CAJ | 학술논문

回顾性分析220例无功能细胞瘤.病例确诊依赖于“三无”:免疫组化阴性染色；无血浆激素水平升高；无激素升高引起的相应症状.发生率占同期垂体瘤的首位(33.13％),男:女为132∶88,老年前期发生率最高(50％～65.91％).临床特征为(1)卒中发生率高(38.18％),(2)主要压迫症状包括视野异常(85.00％),头痛(80％),视力下降(68.66％)及垂体功能低下症状(44.04％)等.影像特点有(1)2 ～4 cm者占71.82％,(2)侵袭Ⅲ、Ⅳ级者达83.64％.
회고성분석220례무공능세포류.병례학진의뢰우“삼무”:면역조화음성염색；무혈장격소수평승고；무격소승고인기적상응증상.발생솔점동기수체류적수위(33.13％),남:녀위132∶88,노년전기발생솔최고(50％～65.91％).림상특정위(1)졸중발생솔고(38.18％),(2)주요압박증상포괄시야이상(85.00％),두통(80％),시력하강(68.66％)급수체공능저하증상(44.04％)등.영상특점유(1)2 ～4 cm자점71.82％,(2)침습Ⅲ、Ⅳ급자체83.64％.
A retrospective analysis was carried out in 220 cases of nonfunctional pituitary adenoma (NFA).The diagnosis was based on negative immunohistochemical staining,no elevation of plasma hormone level,and no symptom caused by increased hormone level.Incidence of NFA was the highest(33.13％) among the pituitary tumors.It was more common in males than in females (132 ∶ 88).The highest prevalence resided in the elder group.N FA often caused pituitary apoplexy,and mainly presented as compression symptoms including visual field abnormalities (85.00％),headache (80％),hypopsia (68.66％),and other symptoms of hypopituitarism (44.04％).Imaging features showed tumor size usually within 2-4 cm (71.82％),and aggregated degree Ⅲ or Ⅳ (83.64％).