CAJ | 학술논문

回顾分析三发性甲状旁腺功能亢进症患者6例.其中骨骼疼痛3例,双下肢无力1例,双下肢酸胀1例,碱性磷酸酶升高1例.既往有肾衰竭史5例,另1例有严重肠道吸收障碍,其中行肾移植4例.X线显示骨膜下骨质吸收、骨质脱钙或伴纤维素性骨炎.骨密度示有骨质疏松5例,其中1例发生骨折.有2例出现骨外钙化,1例左房室膜钙化,1例臀部钙化.4例患者血钙升高,2例血钙正常,4例患者血磷下降,6例甲状旁腺素(PTH)均升高.术后甲状旁腺病理显示甲状旁腺腺瘤4例,增生2例.手术后6例患者血钙降低,补钙10～ 15 d后恢复正常,PTH均恢复正常.
회고분석삼발성갑상방선공능항진증환자6례.기중골격동통3례,쌍하지무력1례,쌍하지산창1례,감성린산매승고1례.기왕유신쇠갈사5례,령1례유엄중장도흡수장애,기중행신이식4례.X선현시골막하골질흡수、골질탈개혹반섬유소성골염.골밀도시유골질소송5례,기중1례발생골절.유2례출현골외개화,1례좌방실막개화,1례둔부개화.4례환자혈개승고,2례혈개정상,4례환자혈린하강,6례갑상방선소(PTH)균승고.술후갑상방선병리현시갑상방선선류4례,증생2례.수술후6례환자혈개강저,보개10～ 15 d후회복정상,PTH균회복정상.
The data of 6 patients with tertiary hyperparathyroidism were retrospectively analyzed.The first symptom in 3 patients was bone ache,1 with lower extremity weakness,1 with swelling of lower limbs,and 1 with increase serum alkaline phosphatase.5 patients had past history of renal failure,1 case suffered from severe intestinal malabsorption,and 4 of them had renal transplantation.X-ray showed subperiosteal bone resorption,bone demineralization,or cellulose osteitis.5 subjects presented with osteoporosis,and 1 of them had fractures.Left atrioventricular membrane calcification and gluteal calcification were found in each of 2 cases.4 patients suffered from hypercalcaemia,2 patients with normal serum calcium,4 with hypophosphataemia,and 6 with high levels of PTH.Pathological results showed adenoma in parathyroid gland in 4 patients and enlarged parathyroid glands in 2 patients.Serum calcium and PTH levels returned to normal after operation and calcium supplement.