CAJ | 학술논문

目的分析和讨论立体定向穿刺活检技术在下丘脑病变诊断中的应用,为疑难病例提供诊断手段.方法分析和总结2例临床表现为下丘脑综合征,影像学显示为下丘脑占位的患者,经立体定向穿刺活检明确病理诊断.结果 2例患者均未发生穿刺相关并发症,分别明确诊断为下丘脑炎性肉芽肿和胚胎生殖细胞肿瘤.给予相应的治疗后其症状及影像学均获得不同程度的改善.复习2001年后文献中报道行立体定向穿刺活检的病例,其成功率为86％～ 99％,活检病理与手术病理的一致率为79％～96.7％,其并发症总体发生率＜5％.结论立体定向穿刺创伤小、准确率高,有利于及早明确下丘脑占位病变性质,为后续治疗提供方案.
목적 분석화토론입체정향천자활검기술재하구뇌병변진단중적응용,위의난병례제공진단수단.방법 분석화총결2례림상표현위하구뇌종합정,영상학현시위하구뇌점위적환자,경입체정향천자활검명학병리진단.결과 2례환자균미발생천자상관병발증,분별명학진단위하구뇌염성육아종화배태생식세포종류.급여상응적치료후기증상급영상학균획득불동정도적개선.복습2001년후문헌중보도행입체정향천자활검적병례,기성공솔위86％～ 99％,활검병리여수술병리적일치솔위79％～96.7％,기병발증총체발생솔＜5％.결론 입체정향천자창상소、준학솔고,유리우급조명학하구뇌점위병변성질,위후속치료제공방안.
Objective To analyze the use of stereotactic biopsy in the diagnosis of hypothalamus lesions,which could be an alternative method for cases with diagnostic problems.Methods Two cases of hypothalamus syndrome with a mass in the area of hypothalamus were presented.By image-guided stereotactic biopsy,correct diagnosis was made.Results These 2 cases diagnosed was granulomatous inflammation and embryonic germ cell tumor respectively,without any biopsy-related complications.The features of disease were improved after corresponding treatment.Similar reports published since 2001 were then reviewed.86％-99％ patients can be diagnosed pathologically by stereotactic biopsy,with accuracy rates of 79％-96.7％.The overall biopsy-related complications were found in less than 5 ％ of total patients.Conclusions Stereotactic biopsy is a safe and reliable way for making pathological diagnosis and may help selecting appropriate management for hypothalamus lesions.