CAJ | 학술논문

于2009年采用分层抽样的方法对福建省宁德市5 523名畲族人群进行流行病学调查,最终5 080名研究对象进入研究.该人群中甲状腺功能异常的患病率为12.1％,TSH低于正常范围者有124名(2.4％),高于正常范围者有491名(9.7％).甲状腺过氧化物酶抗体(TPOAb)阳性率为10.8％(男性7.4％及女性13.5％,P＜0.01),TSH异常的人群中TPOAb阳性率较TSH正常者高.研究结果显示,TSH与TPOAb关系密切,在甲状腺功能亢进及甲状腺功能减退人群中,自身免疫可能均起着重要的作用.
우2009년채용분층추양적방법대복건성저덕시5 523명여족인군진행류행병학조사,최종5 080명연구대상진입연구.해인군중갑상선공능이상적환병솔위12.1％,TSH저우정상범위자유124명(2.4％),고우정상범위자유491명(9.7％).갑상선과양화물매항체(TPOAb)양성솔위10.8％(남성7.4％급녀성13.5％,P＜0.01),TSH이상적인군중TPOAb양성솔교TSH정상자고.연구결과현시,TSH여TPOAb관계밀절,재갑상선공능항진급갑상선공능감퇴인군중,자신면역가능균기착중요적작용.
In 2009,5 523 participants of She nationality living in Ningde City of Fujian province were multistage-stratified and randomly collected,and 5 080 were enrolled in analysis eventually.The TSH screening (reference range,0.3-3.0 mIU/L) revealed biochemical hyperthyroidism in 2.4％ (2.1％ of males and 2.7％ of females) and biochemical hypothyroidism in 9.7％ (7.4％ of males and 11.4％ of females) of the participants.The prevalence of positive TPOAbs was 10.8％ (7.4％ of males and 13.5％ of females).TSH values outside the normal reference range were associated with a higher prevalence of positive TPOAbs,indicating that autoimmunity seems to be an important factor in both hyperthyroidism and hypothyroidism.