CAJ | 학술논문

探讨亚临床甲状腺功能减退(SCH)与代谢综合征(MS)及其组分的关系.2 252名20岁以上体检人群SCH总体检出率为4.88％,其中男性2.17％,女性7.30％,女性显著高于男性(P＜0.01);男女性SCH检出率均以70岁以上年龄组最高;随年龄增长,女性SCH的检出率逐渐增高(P＜0.01).SCH组的体重指数、甘油三酯、低密度脂蛋白胆固醇水平显著高于甲状腺功能正常组(P＜0.05);高密度脂蛋白胆固醇显著低于甲状腺功能正常组(P＜0.05);SCH组高血压、血脂异常及MS的检出率均显著高于甲状腺功能正常组(P＜0.05);MS组TSH水平和SCH的检出率显著高于非MS组(均P＜0.05).女性SCH检出率随年龄增长而升高,多种代谢异常在SCH患者中呈现集聚倾向,SCH与MS关系密切.
탐토아림상갑상선공능감퇴(SCH)여대사종합정(MS)급기조분적관계.2 252명20세이상체검인군SCH총체검출솔위4.88％,기중남성2.17％,녀성7.30％,녀성현저고우남성(P＜0.01);남녀성SCH검출솔균이70세이상년령조최고;수년령증장,녀성SCH적검출솔축점증고(P＜0.01).SCH조적체중지수、감유삼지、저밀도지단백담고순수평현저고우갑상선공능정상조(P＜0.05);고밀도지단백담고순현저저우갑상선공능정상조(P＜0.05);SCH조고혈압、혈지이상급MS적검출솔균현저고우갑상선공능정상조(P＜0.05);MS조TSH수평화SCH적검출솔현저고우비MS조(균P＜0.05).녀성SCH검출솔수년령증장이승고,다충대사이상재SCH환자중정현집취경향,SCH여MS관계밀절.
The relationship between subclinical hypothyroidism (SCH) and the components of metabolic syndrome (MS) was explored.A total of 2 252 subjects aged 20 to 79 years from medical examination were identified.The prevalence of SCH was 4.88％.The rate of 7.30％ in female was markedly higher than 2.17％ in male(P＜0.01).The highest SCH prevalence in adults was in the ≥70 years old group.The prevalence of SCH in female was increased with age(P＜0.01).Compared with the euthyroid group,body mass index,triglyceride,and low density lipoprotein-cholesterol were significantly elevated (P＜0.05),while high density lipoprotein-cholesterol was significantly decreased in SCH group(P＜0.05).The incidences of hypertension,dyslipidosis,and MS in SCH group were significantly higher than those in euthyroid group(P＜0.05 or P＜0.01) ; Serum TSH in the MS group was higher than that in the Non-MS group[(2.43 ± 1.55 vs 2.21 ± 1.48) mU/L,P＜0.01].The incidence of SCH in MS group was significantly higher than that in the Non-MS group (7.69％ vs 4.25％,P＜0.05).The prevalence of SCH in women was increased with age.Multiple factors of dysbolism were clustered in subjects with SCH.There is a correlation between SCH and MS.