中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2014年
4期
307-311
,共5页
吴敏%张捷%金志斌%杨建%彭娟%曹秋月
吳敏%張捷%金誌斌%楊建%彭娟%曹鞦月
오민%장첩%금지빈%양건%팽연%조추월
超声%甲状腺结节%弹性成像%应变率比值%细针穿刺
超聲%甲狀腺結節%彈性成像%應變率比值%細針穿刺
초성%갑상선결절%탄성성상%응변솔비치%세침천자
Ultrasound%Thyroid nodule%Elastography%Strain ratio%Fine-needle aspiration
目的 评价弹性应变率比值(SR)在超声引导下甲状腺细针穿刺(US-FNA)中的应用价值.方法 对216例患者共222例甲状腺结节的临床资料、二维超声图像和SR进行logistic回归分析,评价各变量尤其是SR的诊断效能,统计SR法、US-FNA法和联合法诊断甲状腺结节良恶性的灵敏度、特异度和准确率.结果 多因素分析筛选出3个具有统计学意义的特征变量,按OR值高低依次为:SR、结节回声、年龄.SR法、US-FNA法和联合法诊断甲状腺结节良恶性的灵敏度、特异度和准确率分别为85.4％、82.1％、83.3％;91.5％、82.1％、85.6％;97.6％、94.3％、95.5％.结论 SR＜0.5是诊断甲状腺恶性结节最重要的危险因素,SR联合US-FNA法后显著提高了US-FNA诊断的灵敏度、特异度和准确率,在US-FNA中具有重要的临床意义.
目的 評價彈性應變率比值(SR)在超聲引導下甲狀腺細針穿刺(US-FNA)中的應用價值.方法 對216例患者共222例甲狀腺結節的臨床資料、二維超聲圖像和SR進行logistic迴歸分析,評價各變量尤其是SR的診斷效能,統計SR法、US-FNA法和聯閤法診斷甲狀腺結節良噁性的靈敏度、特異度和準確率.結果 多因素分析篩選齣3箇具有統計學意義的特徵變量,按OR值高低依次為:SR、結節迴聲、年齡.SR法、US-FNA法和聯閤法診斷甲狀腺結節良噁性的靈敏度、特異度和準確率分彆為85.4％、82.1％、83.3％;91.5％、82.1％、85.6％;97.6％、94.3％、95.5％.結論 SR＜0.5是診斷甲狀腺噁性結節最重要的危險因素,SR聯閤US-FNA法後顯著提高瞭US-FNA診斷的靈敏度、特異度和準確率,在US-FNA中具有重要的臨床意義.
목적 평개탄성응변솔비치(SR)재초성인도하갑상선세침천자(US-FNA)중적응용개치.방법 대216례환자공222례갑상선결절적림상자료、이유초성도상화SR진행logistic회귀분석,평개각변량우기시SR적진단효능,통계SR법、US-FNA법화연합법진단갑상선결절량악성적령민도、특이도화준학솔.결과 다인소분석사선출3개구유통계학의의적특정변량,안OR치고저의차위:SR、결절회성、년령.SR법、US-FNA법화연합법진단갑상선결절량악성적령민도、특이도화준학솔분별위85.4％、82.1％、83.3％;91.5％、82.1％、85.6％;97.6％、94.3％、95.5％.결론 SR＜0.5시진단갑상선악성결절최중요적위험인소,SR연합US-FNA법후현저제고료US-FNA진단적령민도、특이도화준학솔,재US-FNA중구유중요적림상의의.
Objective To evaluate the value of elastic strain ratio (SR) in ultrasound guided fine needle aspiration (US-FNA) of thyroid nodule.Methods A total of 222 thyroid nodules from 216 patients were reviewed and analyzed by Logistic regression of clinical data,2D ultrasound,and SR.The odds ratios of variables in the equation were compared to assess various variables,especially of SR in the diagnosis.The sensitivity,specificity,and accuracy of the SR method,US-FNA method,and combined method were calculated.Results Three statistically significant features finally entered the Logistic regression model,followed by SR,echo,and age according to the odds ratio.The sensitivity,specificity,and accuracy of the SR method,US-FNA method and combined method were 85.4％,82.1％,83.3％ ; 91.5％,82.1％,85.6％ ; 97.6％,94.3％,95.5％ respectively.Conclusions SR＜0.5 is the most important risk factor in differential diagnosis of thyroid malignant nodules from benign nodules.SR raises the sensitivity,specificity,and accuracy of US-FNA method and plays an important role in diagnosing thyroid nodules via US-FNA.
