CAJ | 학술논문

自然界中几乎所有的多细胞物种都与原核生物维持一种共生关系.在人类,这种宿主与微生物菌群之间的共生关系在胃肠道中尤为突出.技术和观念上的更新使我们能够更加充分的认识到他们对人类的健康与疾病的重要作用.已有研究表明肠道菌群的失调与肥胖,2型糖尿病等代谢性疾病有关.本综述旨在探寻人类与肠道微生物菌群的相互识别和相互作用、肠道微生物菌群对人类代谢性疾病的作用及代谢性手术对肠道菌群的影响,从而为这些疾病的治疗探寻一条新的途径.
자연계중궤호소유적다세포물충도여원핵생물유지일충공생관계.재인류,저충숙주여미생물균군지간적공생관계재위장도중우위돌출.기술화관념상적경신사아문능구경가충분적인식도타문대인류적건강여질병적중요작용.이유연구표명장도균군적실조여비반,2형당뇨병등대사성질병유관.본종술지재탐심인류여장도미생물균군적상호식별화상호작용、장도미생물균군대인류대사성질병적작용급대사성수술대장도균군적영향,종이위저사질병적치료탐심일조신적도경.
Almost all multicellular organisms have a symbiotic relationship with prokaryotes in nature.In humans,the interaction between host and microbial flora is particularly important in the gastrointestinal tract.Technical and conceptual advances have enabled us to establish its role in human health and disease.Studies have shown that disorder of gut microbiota may participate in the development of metabolic diseases,such as obesity and type 2 diabetes.This review opens up new ideas to find strategies for modifying gut microbiota to impact on the occurrence of metabolic diseases.