CAJ | 학술논문

本研究采用前瞻性队列研究方法,以参加2006～2007年度开滦集团职工健康体检的101 510名职工中空腹血糖(FPG) ＜7.0 mmol/L、无糖尿病病史、未使用降糖药物且FPG及睡眠资料完整的87 540名职工作为观察队列,排除2010～2011年度未参加体检者、FPG资料缺失者,最终纳入统计分析的有效数据为60715名.依据基线睡眠时间将观察对象分为睡眠时间不足组(＜7 h/d)、睡眠时间充足组(7～9h/d)、睡眠时间过长组(≥9 h/d).结果显示,至2010～ 2011年度体检结束时,＜7 h/d、7～9 h/d和≥9 h/d组的糖尿病发病率分别为5.49％、4.94％、5.61％(男性分别为5.70％、5.32％、6.27％;女性分别为4.49％、3.74％、3.77％).多因素logistic回归分析显示,校正了年龄、性别等因素后,与7～9 h/d组比较,＜7 h/d组、≥9h/d组新发糖尿病发生风险的RR值分别为1.09、1.28,在不同性别人群中校正上述因素后,其新发糖尿病的发生风险也无明显增加.
본연구채용전첨성대렬연구방법,이삼가2006～2007년도개란집단직공건강체검적101 510명직공중공복혈당(FPG) ＜7.0 mmol/L、무당뇨병병사、미사용강당약물차FPG급수면자료완정적87 540명직공작위관찰대렬,배제2010～2011년도미삼가체검자、FPG자료결실자,최종납입통계분석적유효수거위60715명.의거기선수면시간장관찰대상분위수면시간불족조(＜7 h/d)、수면시간충족조(7～9h/d)、수면시간과장조(≥9 h/d).결과현시,지2010～ 2011년도체검결속시,＜7 h/d、7～9 h/d화≥9 h/d조적당뇨병발병솔분별위5.49％、4.94％、5.61％(남성분별위5.70％、5.32％、6.27％;녀성분별위4.49％、3.74％、3.77％).다인소logistic회귀분석현시,교정료년령、성별등인소후,여7～9 h/d조비교,＜7 h/d조、≥9h/d조신발당뇨병발생풍험적RR치분별위1.09、1.28,재불동성별인군중교정상술인소후,기신발당뇨병적발생풍험야무명현증가.
A total of 101 510 employees of Kailuan Group took part in the health examination from 2006 to 2007.87 540 subjects with fasting plasma glucose (FPG) ＜7.0 mmol/L,no history of diabetes,complete FPG and sleep time data,and without using hypoglycemic agents were selected as the observation cohort.Subjects who did not participate in the health examination between 2010 to 2011 and had incomplete examination data were excluded and 60 715 subjects were included for final analysis.According to the basal sleep time,the observation population was divided into three groups:sleep time＜7 h/d group,7-9 h/d group,and≥9 h/d group.The results showed that by the end of the health examination in 2010-2011,the incidences of newly onset diabetes (NOD) in＜7 h/d,7-9 h/d,and ≥9 h/d groups were 5.49％,4.94％,5.61％,respectively in whole population (5.70％,5.32％,6.27％ in male;4.49％,3.74％,3.77％ in female).Multiple logistic regression analysis showed that compared with 7-9 h/d group,the risk of NOD was not significantly increased in ＜7 h/d group and ≥9 h/d group after adjusting age,gender,and other risk factors,with the RR value 1.09 and 1.28.