CAJ | 학술논문

本研究纳入4602名南宁地区常规体检者,检测分析尿酸、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇.结果显示体检人群高尿酸血症总患病率为19.8％,其中男性为28.8％,女性为9.4％;高尿酸血症组中尿酸与血脂水平高于尿酸正常组(均P＜0.01);尿酸与总胆固醇、甘油三酯、低密度脂蛋白胆固醇呈正相关,与高密度脂蛋白胆固醇呈负相关;体检人群高总胆固醇血症患病率为30.8％,高甘油三酯血症为22.2％;Logistic多因素回归分析得出男性、高总胆固醇、高甘油三酯、高低密度脂蛋白胆固醇可能为高尿酸血症的危险因素;高密度脂蛋白胆固醇为保护因素.结果提示广西南宁地区高尿酸血症患病率较高,高尿酸水平与血脂异常密切相关.早期加强对高尿酸血症的干预,能有效减少相关疾病的发生.
본연구납입4602명남저지구상규체검자,검측분석뇨산、총담고순、감유삼지、고밀도지단백담고순、저밀도지단백담고순.결과현시체검인군고뇨산혈증총환병솔위19.8％,기중남성위28.8％,녀성위9.4％;고뇨산혈증조중뇨산여혈지수평고우뇨산정상조(균P＜0.01);뇨산여총담고순、감유삼지、저밀도지단백담고순정정상관,여고밀도지단백담고순정부상관;체검인군고총담고순혈증환병솔위30.8％,고감유삼지혈증위22.2％;Logistic다인소회귀분석득출남성、고총담고순、고감유삼지、고저밀도지단백담고순가능위고뇨산혈증적위험인소;고밀도지단백담고순위보호인소.결과제시엄서남저지구고뇨산혈증환병솔교고,고뇨산수평여혈지이상밀절상관.조기가강대고뇨산혈증적간예,능유효감소상관질병적발생.
In 4 602 subjects for routine check-up,blood uric acid,total cholesterol,triglyceride,high density lipoprotein-cholesterol,and low density lipoprotein-cholesterol were determined.Results showed that the overall prevalence of hyperuricemia in Nanning,Guangxi was 19.8％ (28.8％ in male,9.4％ in female).Blood uric acid and lipids in hyperuricemia group were higher than those in normal uric acid group(all P＜0.01).Serum uric acid had a positive correlation with total cholesterol,triglyceride,low density lipoprotein-cholesterol,but it was negatively correlated with serum high density lipoprotein-cholesterol.The prevalence of hypercholesterolemia was 30.8％,and that of hypertriglyceridemia was 22.2％.Logistic multi-factor regression analysis showed that men,high total cholesterol,triglyceride,and low density lipoprotein-cholesterol could be independent risk factors for hyperuricemia,and that high density lipoprotein-cholesterol was a protective factor.The prevalence of hyperuricemia in population of Nanning,Guangxi during health examination is high.Hyperuricemia is closely associated with dyslipidemia.Timely intervention of hyperuricemia can reduce the related diseases effectively.