中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2014年
6期
460-463
,共4页
徐芳华%霍亚南%吴明斌%刘精东%章玉玲
徐芳華%霍亞南%吳明斌%劉精東%章玉玲
서방화%곽아남%오명빈%류정동%장옥령
代谢综合征%中老年女性%产次
代謝綜閤徵%中老年女性%產次
대사종합정%중노년녀성%산차
Metabolic syndrome%Middle-aged and elderly women%Parity
目的 了解南昌社区中老年女性产次等生育相关因素与代谢综合征的相关性.方法 对南昌社区40岁及以上女性常住居民进行问卷调查.检测身高、体重、血压、血糖、血脂.获得有效人数5 894名.按照2004年中华医学会糖尿病学分会代谢综合征标准诊断.分析年龄、受教育程度、职业、婚姻状况、产次、巨大儿生育史、哺乳时间、月经初潮年龄、绝经年龄与代谢综合征的关系.首先行单因素logistic分析,有统计学意义者(P＜0.05)进一步行二分类logistic回归分析,计算OR值及其95％置信区间(CI).结果 单因素分析显示,年龄、文化程度、职业、产次、哺乳时间、绝经年龄是代谢综合征的影响因素(均P＜0.05);婚姻状况、流产次数、巨大儿生育史、月经初潮年龄与代谢综合征不相关(均P＞0.05).二元logistic回归分析显示,相对于年龄40 ～ 49岁组而言,50～59岁、60 ～ 69岁、≥70岁组的患病风险逐渐增加,分别为OR=1.51(95％ CI0.98 ～2.32)、OR=2.10(95％ CI 1.34 ～ 3.30)、OR=2.63(95％CI1.61～4.31);非体力劳动者相对于体力劳动者患病风险增加,OR=1.33(95％ CI 1.04～1.70).相对于产次1次组而言,2产次、3产次、4产次的患病风险逐渐增加,分别为OR=1.46(95％ CI 1.14～1.88)、OR=1.78(95％ CI 1.30 ～2.43)、OR=1.84 (95％ CI 1.24 ～ 2.72);随着绝经年龄增加,患代谢综合征的患病风险降低,绝经年龄每推迟1岁,代谢综合征患病风险降低6％,OR=0.94(95％ CI0.90～0.99).文化程度和哺乳时间对代谢综合征的相关性无显著意义(P＞0.05).结论 多产次、早绝经、少体力劳动和增龄可能会增加女性代谢综合征的发生风险.
目的 瞭解南昌社區中老年女性產次等生育相關因素與代謝綜閤徵的相關性.方法 對南昌社區40歲及以上女性常住居民進行問捲調查.檢測身高、體重、血壓、血糖、血脂.穫得有效人數5 894名.按照2004年中華醫學會糖尿病學分會代謝綜閤徵標準診斷.分析年齡、受教育程度、職業、婚姻狀況、產次、巨大兒生育史、哺乳時間、月經初潮年齡、絕經年齡與代謝綜閤徵的關繫.首先行單因素logistic分析,有統計學意義者(P＜0.05)進一步行二分類logistic迴歸分析,計算OR值及其95％置信區間(CI).結果 單因素分析顯示,年齡、文化程度、職業、產次、哺乳時間、絕經年齡是代謝綜閤徵的影響因素(均P＜0.05);婚姻狀況、流產次數、巨大兒生育史、月經初潮年齡與代謝綜閤徵不相關(均P＞0.05).二元logistic迴歸分析顯示,相對于年齡40 ～ 49歲組而言,50～59歲、60 ～ 69歲、≥70歲組的患病風險逐漸增加,分彆為OR=1.51(95％ CI0.98 ～2.32)、OR=2.10(95％ CI 1.34 ～ 3.30)、OR=2.63(95％CI1.61～4.31);非體力勞動者相對于體力勞動者患病風險增加,OR=1.33(95％ CI 1.04～1.70).相對于產次1次組而言,2產次、3產次、4產次的患病風險逐漸增加,分彆為OR=1.46(95％ CI 1.14～1.88)、OR=1.78(95％ CI 1.30 ～2.43)、OR=1.84 (95％ CI 1.24 ～ 2.72);隨著絕經年齡增加,患代謝綜閤徵的患病風險降低,絕經年齡每推遲1歲,代謝綜閤徵患病風險降低6％,OR=0.94(95％ CI0.90～0.99).文化程度和哺乳時間對代謝綜閤徵的相關性無顯著意義(P＞0.05).結論 多產次、早絕經、少體力勞動和增齡可能會增加女性代謝綜閤徵的髮生風險.
목적 료해남창사구중노년녀성산차등생육상관인소여대사종합정적상관성.방법 대남창사구40세급이상녀성상주거민진행문권조사.검측신고、체중、혈압、혈당、혈지.획득유효인수5 894명.안조2004년중화의학회당뇨병학분회대사종합정표준진단.분석년령、수교육정도、직업、혼인상황、산차、거대인생육사、포유시간、월경초조년령、절경년령여대사종합정적관계.수선행단인소logistic분석,유통계학의의자(P＜0.05)진일보행이분류logistic회귀분석,계산OR치급기95％치신구간(CI).결과 단인소분석현시,년령、문화정도、직업、산차、포유시간、절경년령시대사종합정적영향인소(균P＜0.05);혼인상황、유산차수、거대인생육사、월경초조년령여대사종합정불상관(균P＞0.05).이원logistic회귀분석현시,상대우년령40 ～ 49세조이언,50～59세、60 ～ 69세、≥70세조적환병풍험축점증가,분별위OR=1.51(95％ CI0.98 ～2.32)、OR=2.10(95％ CI 1.34 ～ 3.30)、OR=2.63(95％CI1.61～4.31);비체력노동자상대우체력노동자환병풍험증가,OR=1.33(95％ CI 1.04～1.70).상대우산차1차조이언,2산차、3산차、4산차적환병풍험축점증가,분별위OR=1.46(95％ CI 1.14～1.88)、OR=1.78(95％ CI 1.30 ～2.43)、OR=1.84 (95％ CI 1.24 ～ 2.72);수착절경년령증가,환대사종합정적환병풍험강저,절경년령매추지1세,대사종합정환병풍험강저6％,OR=0.94(95％ CI0.90～0.99).문화정도화포유시간대대사종합정적상관성무현저의의(P＞0.05).결론 다산차、조절경、소체력노동화증령가능회증가녀성대사종합정적발생풍험.
Objective To investigate the relationship of parity and other reproduction-associated factors with metabolic syndrome(MS) in middle-aged and elderly women in Nanchang community.Methods Female permanent residents over 40 years old were sampled for a routine examination and a questionnaire survey covering basic information,5 894 subjects were enrolled and identified as effective cases.MS was diagnosed according to the standard of China Diabetes Society in 2004.Factors including age,education,profession,marital status,parity,child-bearing history of macrosomia,breastfeeding,menarche age,and menopausal age were analyzed in order to find their relationship with MS.The univariate logistic analysis was followed by binary logistic regression analysis if P＜0.05,and OR value and confidence interval were calculated.Results Univariate logistic regression analysis showed that age,education,profession,parity,breastfeeding,and menopausal age were influencing factors of MS (all P ＜ 0.05).There was no correlation to marital status,miscarriage history,child-bearing history of macrosomia,menarche age with MS(all P＞0.05).Binary Logistic regression analysis showed that the risk of MS increased with age:OR =1.51 (95 ％ CI 0.98-2.32) during 50-59 years,OR =2.10 (95 ％ CI 1.34-3.30) during 60-69 years,and OR =2.63 (95 ％ CI 1.61-4.31) in cases aged over 70 years,as compared to the group aged 40-49 years.The risk in non-manual workers increased about 34 percent OR =1.33 (95 ％ CI 1.04-1.70),compared with manual workers.The risk of MS increased with parity,being OR =1.46 (95％ CI 1.14-1.88),OR =1.78 (95％ CI 1.30-2.43),and OR =1.84 (95％ CI 1.24-2.72),with 2,3,and 4 child-bearings respectively as compared to cases with only one childbearing.The risk of MS was reduced with advancing menopausal age being about 6 percent reduction with each increased year of menopausal age(OR =0.94,95％ CI 0.90-0.99).There was no difference between education,breastfeeding and MS(P＞005).Conclusion Multiple parity,earlier menopausal age,less manual work,and aging seem to be the risk factors of MS in women.
