中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
1期
28-30
,共3页
肺间质病变%肺功能%肺部影像学%临床表现
肺間質病變%肺功能%肺部影像學%臨床錶現
폐간질병변%폐공능%폐부영상학%림상표현
Interstitial lung disease%Pulmonary function%Pulmonary image%Clinical manifestations
目的 提高对结缔组织病肺间质病变的认识及诊断.方法 回顾性分析124例结缔组织病肺间质病变患者呼吸系统的临床表现、肺功能检查、肺部影像学特点、有无肺动脉高压、肺功能与肺部影像学关系.结果 124例结缔组织病肺间质病变患者呼吸系统临床表现为咳嗽、咳痰、气短、胸闷憋气,严重时表现为活动耐量下降、呼吸闲难.64例行肺功能检查均有弥散功能减低,其中26例为单纯弥散功能减低,32例为限制性通气功能障碍伴弥散功能减低,4例为混合性通气功能障碍伴弥散功能减低,2例为阻塞性通气功能障碍伴弥散功能减低.22例合并有肺动脉高压.肺间质病变在影像学上可有结节影、索条影、斑片影、网格影、磨玻璃影、肺大泡等多种改变.32例限制性通气功能障碍伴弥散功能减低患者中有15例表现为网格样、纤维化样改变,26例单纯弥散功能减低患者中有8例表现为网格样、纤维化样改变.结论 结缔组织病肺间质病变患者呼吸系统表现多种多样,肺功能检查主要表现为限制性通气功能障碍伴弥散功能减低.混合性结缔组织病、重叠综合征、系统性红斑狼疮、系统性硬化症是较易出现肺间质病变合并肺动脉高压的结缔组织病.结缔组织病肺间质病变在影像学上可有多种多样改变,影像学上表现为网格样、纤维化样改变的患者肺功能易出现限制性通气伴弥散功能障碍.
目的 提高對結締組織病肺間質病變的認識及診斷.方法 迴顧性分析124例結締組織病肺間質病變患者呼吸繫統的臨床錶現、肺功能檢查、肺部影像學特點、有無肺動脈高壓、肺功能與肺部影像學關繫.結果 124例結締組織病肺間質病變患者呼吸繫統臨床錶現為咳嗽、咳痰、氣短、胸悶憋氣,嚴重時錶現為活動耐量下降、呼吸閒難.64例行肺功能檢查均有瀰散功能減低,其中26例為單純瀰散功能減低,32例為限製性通氣功能障礙伴瀰散功能減低,4例為混閤性通氣功能障礙伴瀰散功能減低,2例為阻塞性通氣功能障礙伴瀰散功能減低.22例閤併有肺動脈高壓.肺間質病變在影像學上可有結節影、索條影、斑片影、網格影、磨玻璃影、肺大泡等多種改變.32例限製性通氣功能障礙伴瀰散功能減低患者中有15例錶現為網格樣、纖維化樣改變,26例單純瀰散功能減低患者中有8例錶現為網格樣、纖維化樣改變.結論 結締組織病肺間質病變患者呼吸繫統錶現多種多樣,肺功能檢查主要錶現為限製性通氣功能障礙伴瀰散功能減低.混閤性結締組織病、重疊綜閤徵、繫統性紅斑狼瘡、繫統性硬化癥是較易齣現肺間質病變閤併肺動脈高壓的結締組織病.結締組織病肺間質病變在影像學上可有多種多樣改變,影像學上錶現為網格樣、纖維化樣改變的患者肺功能易齣現限製性通氣伴瀰散功能障礙.
목적 제고대결체조직병폐간질병변적인식급진단.방법 회고성분석124례결체조직병폐간질병변환자호흡계통적림상표현、폐공능검사、폐부영상학특점、유무폐동맥고압、폐공능여폐부영상학관계.결과 124례결체조직병폐간질병변환자호흡계통림상표현위해수、해담、기단、흉민별기,엄중시표현위활동내량하강、호흡한난.64례행폐공능검사균유미산공능감저,기중26례위단순미산공능감저,32례위한제성통기공능장애반미산공능감저,4례위혼합성통기공능장애반미산공능감저,2례위조새성통기공능장애반미산공능감저.22례합병유폐동맥고압.폐간질병변재영상학상가유결절영、색조영、반편영、망격영、마파리영、폐대포등다충개변.32례한제성통기공능장애반미산공능감저환자중유15례표현위망격양、섬유화양개변,26례단순미산공능감저환자중유8례표현위망격양、섬유화양개변.결론 결체조직병폐간질병변환자호흡계통표현다충다양,폐공능검사주요표현위한제성통기공능장애반미산공능감저.혼합성결체조직병、중첩종합정、계통성홍반랑창、계통성경화증시교역출현폐간질병변합병폐동맥고압적결체조직병.결체조직병폐간질병변재영상학상가유다충다양개변,영상학상표현위망격양、섬유화양개변적환자폐공능역출현한제성통기반미산공능장애.
Objective To observe the diagnosis of connective tissue diseases with interstitial lung disease.Methods The clinical manifestations of respiratory,pulmonary function tests,lung imaging characteristics,the presence or absence of pulmonary hypertension,pulmonary function in 124 patients with interstitial lung disease associated with connective tissue disease were retrospective analyzed.Results Cough,expectoration,shortness of breath,chest stuffiness and choking were common respiratory symptoms.The fall of activity tolerance and dyspnea were serious respiratory symptoms.64 patients had pulmonary function test and all of them showed a decreasing diffusing capacity.Among them,26 only showed diffusing capacity reduction,32 restrictive ventilation defect with diffusing capacity reduction,4 mixed ventilation defect with diffusing capacity reduction and 2 obstructive ventilation defect with diffusing capacity reduction.22 patients had pulmonary artery high pressure.In image,the features of interstitial lung diseases displayed as follows:nodus,steak,patchy sign,grid,ground-glass opacities and bullae of lung.The features of interstitial lung diseases displayed as grid and fibrosis in 15 of 32 restrictive ventilation defect with diffusing capacity reduction.Conclusions The respiratory symptoms of c onnective tissue diseases with interstitial lung disease are various.Pulmonary function of connective tissue diseases with interstitial lung disease primarily displays a restrictive ventilation defect with diffusing capacity reduction.Connective tissue diseases complicated with interstitial lung disease and of pulmonary arterial hypertension easily occur in mixed connective tissue disease (MCTD),overlap connective tissue disease,systemic lupus erythematosus (SLE) and systemic sclerosis(SSc).In image,the features of interstitial lung diseases is various.Among them,grid and fibrosis are related to pulmonary function of restrictive ventilation defect with diffusing capacity reduction.
