中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
2期
157-158
,共2页
冠心病%心绞痛%葛兰心宁%软胶囊
冠心病%心絞痛%葛蘭心寧%軟膠囊
관심병%심교통%갈란심저%연효낭
Coronary heart disease%Angina%Gelanxinning%Soft capsule
目的 观察葛兰心宁软胶囊治疗冠心病心绞痛的临床疗效.方法 将160例冠心病心绞痛患者完全随机分为研究组和对照组,各80例.2组患者均给予抗血小板、降脂药物等常规对症治疗.研究组患者在常规对症治疗基础上给予葛兰心宁软胶囊口服(0.58 g/粒),2粒/次,3次/d;对照组给予复方丹参注射液20 ml加入0.9％氯化钠溶液或5％葡萄糖溶液250 ml静脉滴注,1次/d.疗程为4周.观察并比较2组患者的临床疗效及心电图、心绞痛临床症状改善情况.结果 研究组临床总有效率高于对照组[92.5％(74/80)比85.0％(68/80)],差异有统计学意义(P＜0.01).研究组心电图改善总有效率为96.2％ (77/80),明显高于对照组[82.5％ (66/80)] (P ＜0.01).研究组治疗后临床症状明显改善,与对照组比较,差异有统计学意义(P＜0.05).结论 葛兰心宁软胶囊治疗冠心病心绞痛临床疗效确切、显著.
目的 觀察葛蘭心寧軟膠囊治療冠心病心絞痛的臨床療效.方法 將160例冠心病心絞痛患者完全隨機分為研究組和對照組,各80例.2組患者均給予抗血小闆、降脂藥物等常規對癥治療.研究組患者在常規對癥治療基礎上給予葛蘭心寧軟膠囊口服(0.58 g/粒),2粒/次,3次/d;對照組給予複方丹參註射液20 ml加入0.9％氯化鈉溶液或5％葡萄糖溶液250 ml靜脈滴註,1次/d.療程為4週.觀察併比較2組患者的臨床療效及心電圖、心絞痛臨床癥狀改善情況.結果 研究組臨床總有效率高于對照組[92.5％(74/80)比85.0％(68/80)],差異有統計學意義(P＜0.01).研究組心電圖改善總有效率為96.2％ (77/80),明顯高于對照組[82.5％ (66/80)] (P ＜0.01).研究組治療後臨床癥狀明顯改善,與對照組比較,差異有統計學意義(P＜0.05).結論 葛蘭心寧軟膠囊治療冠心病心絞痛臨床療效確切、顯著.
목적 관찰갈란심저연효낭치료관심병심교통적림상료효.방법 장160례관심병심교통환자완전수궤분위연구조화대조조,각80례.2조환자균급여항혈소판、강지약물등상규대증치료.연구조환자재상규대증치료기출상급여갈란심저연효낭구복(0.58 g/립),2립/차,3차/d;대조조급여복방단삼주사액20 ml가입0.9％록화납용액혹5％포도당용액250 ml정맥적주,1차/d.료정위4주.관찰병비교2조환자적림상료효급심전도、심교통림상증상개선정황.결과 연구조림상총유효솔고우대조조[92.5％(74/80)비85.0％(68/80)],차이유통계학의의(P＜0.01).연구조심전도개선총유효솔위96.2％ (77/80),명현고우대조조[82.5％ (66/80)] (P ＜0.01).연구조치료후림상증상명현개선,여대조조비교,차이유통계학의의(P＜0.05).결론 갈란심저연효낭치료관심병심교통림상료효학절、현저.
Objective To study the efficacy of Gelanxinning soft capsule on the treatment of angina.Methods All 160 patients were randomly divided into research group and control group (80 patients in each group).All patients received standard treatment for coronary artery disease which including aspirin and statin.The patients in research group received Gelanxinning soft capsule (1.16 g each time,three times one day).The control group received Danshen injection (20 ml each time,dissolved in normal saline or 5％ glucose solution 250 ml,one time one day).The clinical efficacy,change of electrocardiography(ECG) and the relief of angina after 4 weeks of treatment were the study endpoint.Results The total effective rate in research group was significantly higher than that in control group [92.5％ (74/80) vs 85.0％ (68/80),P ＜0.01].Seventy-seven patients(96.2％) in the research group showed improvement of ECG,while only 82.5％ (66/80) in the control group showed improvement,and there was significant difference between research group and control group (P ＜ 0.01).As compared with the control group,the clinical symptoms of angina was improved significantly in research group (P ＜ 0.05).Conclusion Gelanxinning soft capsule therapy seems to be effective and obvious for the relief of angina.
