中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
2期
199-200
,共2页
刘志杰%刘世会%盖春莲%李士敏
劉誌傑%劉世會%蓋春蓮%李士敏
류지걸%류세회%개춘련%리사민
癌,肾细胞%肿瘤化疗,区域灌注%栓塞
癌,腎細胞%腫瘤化療,區域灌註%栓塞
암,신세포%종류화료,구역관주%전새
Carcinoma,renal cell%Cancer chemotherapy,regional perfusion%Embolism
目的 探讨术前动脉化疗栓塞对中晚期肾癌手术情况的影响,评价其在临床治疗中的意义.方法 选择中晚期肾癌术前介入化疗栓塞患者20例为术前介入组,同期类似大小肿瘤单纯手术切除患者20例为单纯手术组,分别对2组患者的手术情况进行对比研究.结果 术前介入组所有患者均未发生严重并发症.术前介入组术中平均出血量(183±24)ml,平均输血量(176±38)ml,平均手术时间(92±7) min,均明显少于单纯手术组[平均出血量:(479±70)ml,平均输血量(413±66) ml,平均手术时间(122±10) min](P ＜0.05或P＜0.01)；术前介入组术中见肿瘤体积缩小,瘤体表面静脉萎陷,肾周形成明显水肿带,易于分离；瘤体标本切面见大面积肿瘤组织坏死及纤维组织增生.单纯手术组瘤体表面血管怒张,与周围粘连,分离容易出血.结论 中晚期肾癌患者术前介入治疗可以缩短手术时间,减少术中出血量,提高手术成功率.
目的 探討術前動脈化療栓塞對中晚期腎癌手術情況的影響,評價其在臨床治療中的意義.方法 選擇中晚期腎癌術前介入化療栓塞患者20例為術前介入組,同期類似大小腫瘤單純手術切除患者20例為單純手術組,分彆對2組患者的手術情況進行對比研究.結果 術前介入組所有患者均未髮生嚴重併髮癥.術前介入組術中平均齣血量(183±24)ml,平均輸血量(176±38)ml,平均手術時間(92±7) min,均明顯少于單純手術組[平均齣血量:(479±70)ml,平均輸血量(413±66) ml,平均手術時間(122±10) min](P ＜0.05或P＜0.01)；術前介入組術中見腫瘤體積縮小,瘤體錶麵靜脈萎陷,腎週形成明顯水腫帶,易于分離；瘤體標本切麵見大麵積腫瘤組織壞死及纖維組織增生.單純手術組瘤體錶麵血管怒張,與週圍粘連,分離容易齣血.結論 中晚期腎癌患者術前介入治療可以縮短手術時間,減少術中齣血量,提高手術成功率.
목적 탐토술전동맥화료전새대중만기신암수술정황적영향,평개기재림상치료중적의의.방법 선택중만기신암술전개입화료전새환자20례위술전개입조,동기유사대소종류단순수술절제환자20례위단순수술조,분별대2조환자적수술정황진행대비연구.결과 술전개입조소유환자균미발생엄중병발증.술전개입조술중평균출혈량(183±24)ml,평균수혈량(176±38)ml,평균수술시간(92±7) min,균명현소우단순수술조[평균출혈량:(479±70)ml,평균수혈량(413±66) ml,평균수술시간(122±10) min](P ＜0.05혹P＜0.01)；술전개입조술중견종류체적축소,류체표면정맥위함,신주형성명현수종대,역우분리；류체표본절면견대면적종류조직배사급섬유조직증생.단순수술조류체표면혈관노장,여주위점련,분리용역출혈.결론 중만기신암환자술전개입치료가이축단수술시간,감소술중출혈량,제고수술성공솔.
Objective To investigate the effect of preoperative interventional chemoembolization on tumor histological structure in middle-advanced kidney cancer and to evaluate the clinical significance.Methods Twenty patients who underwent preoperative embolization plus radical nephrectomy were recruited to embolization group and 20 patients who just underwent radical nephrectomy were selected as control group.The surgical conditions were studied.Results All the patients in embolization group had no serious complications.In embolization group,the amount of blood loss during operation was (183 ± 24)ml and the operation time was (92 ± 7)min,which were significantly lower than those in control group [blood loss during operation:(479 ± 70)ml; operation time:(122 ±10) min; P ＜ 0.05 or P ＜ 0.01].In embolization group,the tumor mass softened; its surface pale and the peripheral veins shrinked and the perinephric edema zone was formed,while in control group the tumor surface blood vessels were extented and tumor tissue was adhered with surrounding tissues and bleeding was easy to occur during dissection.Conclusion The preoperative embolization can decrease operation time and blood loss,and increase operation success rate of middle-advanced kidney cancer.
