中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
3期
369-370
,共2页
骨关节炎,膝%健康教育%运动疗法%物理治疗%美洛昔康
骨關節炎,膝%健康教育%運動療法%物理治療%美洛昔康
골관절염,슬%건강교육%운동요법%물리치료%미락석강
Osteoarthritis,knee%Health education%Exercise therapy%Physical therapy%Meloxicam
目的 观察健康教育、运动疗法、物理治疗联合盐酸氨基葡萄糖治疗膝骨关节炎的临床疗效和安全性.方法 选择确诊为膝骨关节炎的患者141例,完全随机分为观察组(70例)和对照组(71例).在口服盐酸氨基葡萄糖的基础上,观察组给予健康教育、运动疗法、物理治疗,对照组给予美洛昔康口服,治疗12周比较2组治疗后临床症状及不良反应情况.结果 2组治疗后20 m步行痛、关节触痛和WOMAC评分均较本组治疗前改善,差异均有统计学意义(P＜0.05)；治疗后,观察组20 m步行痛、关节触痛和WOMAC评分均低于对照组,但组间差异无统计学意义(P＞0.05).治疗12周后,观察组和对照组有效率分别为84.3％(59/70)和78.9％ (56/71),组间差异无统计学意义(x2=0.686,P＞0.05).观察组不良反应发生率[8.6％(6/70)]低于对照组[26.8％(19/71)],差异有统计学意义(x2=7.99,P＜0.05).结论 健康教育、运动疗法、物理治疗联合盐酸氨基葡萄糖治疗膝骨关节炎的疗效肯定、安全性高.
目的 觀察健康教育、運動療法、物理治療聯閤鹽痠氨基葡萄糖治療膝骨關節炎的臨床療效和安全性.方法 選擇確診為膝骨關節炎的患者141例,完全隨機分為觀察組(70例)和對照組(71例).在口服鹽痠氨基葡萄糖的基礎上,觀察組給予健康教育、運動療法、物理治療,對照組給予美洛昔康口服,治療12週比較2組治療後臨床癥狀及不良反應情況.結果 2組治療後20 m步行痛、關節觸痛和WOMAC評分均較本組治療前改善,差異均有統計學意義(P＜0.05)；治療後,觀察組20 m步行痛、關節觸痛和WOMAC評分均低于對照組,但組間差異無統計學意義(P＞0.05).治療12週後,觀察組和對照組有效率分彆為84.3％(59/70)和78.9％ (56/71),組間差異無統計學意義(x2=0.686,P＞0.05).觀察組不良反應髮生率[8.6％(6/70)]低于對照組[26.8％(19/71)],差異有統計學意義(x2=7.99,P＜0.05).結論 健康教育、運動療法、物理治療聯閤鹽痠氨基葡萄糖治療膝骨關節炎的療效肯定、安全性高.
목적 관찰건강교육、운동요법、물리치료연합염산안기포도당치료슬골관절염적림상료효화안전성.방법 선택학진위슬골관절염적환자141례,완전수궤분위관찰조(70례)화대조조(71례).재구복염산안기포도당적기출상,관찰조급여건강교육、운동요법、물리치료,대조조급여미락석강구복,치료12주비교2조치료후림상증상급불량반응정황.결과 2조치료후20 m보행통、관절촉통화WOMAC평분균교본조치료전개선,차이균유통계학의의(P＜0.05)；치료후,관찰조20 m보행통、관절촉통화WOMAC평분균저우대조조,단조간차이무통계학의의(P＞0.05).치료12주후,관찰조화대조조유효솔분별위84.3％(59/70)화78.9％ (56/71),조간차이무통계학의의(x2=0.686,P＞0.05).관찰조불량반응발생솔[8.6％(6/70)]저우대조조[26.8％(19/71)],차이유통계학의의(x2=7.99,P＜0.05).결론 건강교육、운동요법、물리치료연합염산안기포도당치료슬골관절염적료효긍정、안전성고.
Objective To observe the efficacy and safety of health education,exercise therapy,physical therapy combined with glucosamine hydrochloride in the treatment of knee osteoarthritis.Methods Diagnosed with knee osteoarthritis in 141 patients,all were randomly divided into the observation group (70 cases) and control group (71 cases).The observation group was given health education,exercise therapy,physical therapy combined with glucosamine hydrochloride oral,the control group was given glucosamine hydrochloride combined with meloxicam oral,12 weeks of treatment were compared between the 2 groups after treatment of clinical symptoms and the incidence of related adverse events and make a statistical analysis.Results There was significant difference in 2 groups after the treatment of pain on walking for 20 metres,tenderness on palpation and WOMAC were compared with the group before treatment (P ＜ 0.05) ; after the treatment,the observation group of pain on walking for 20 metres,tenderness on palpation and WOMAC were lower than the control group,but no significant difference was found between the two groups (P ＞ 0.05).After 12 weeks of treatment,the observation group and the control group with efficiencies were respectively 84.3％ (59/70) and 78.9％ (56/71),no significant differences was found (x2 =0.686,P ＞0.05).The incidence of related adverse events was [8.6％ (6/70)] in observation group were lower than in the control group [26.8％ (19/71)],there was significant difference (x2 =7.99,P ＜ 0.05).Conclusion Health education,exercise therapy,physical therapy combined with glucosamine hydrochloride in the treatment of knee osteoarthritis is effective and safe.
