中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
4期
531-532
,共2页
舒芬太尼%丙泊酚%胸腹部手术%老年人
舒芬太尼%丙泊酚%胸腹部手術%老年人
서분태니%병박분%흉복부수술%노년인
Sufentanil%Propofol%Thoracic and abdominal operation%Aged
目的 观察不同浓度舒芬太尼复合丙泊酚对老年胸腹部手术患者的临床麻醉效果.方法 选取56例行胸腹部手术的老年患者完全随机分为观察组和对照组,各28例.对照组给予0.3μg/(kg·min)舒芬太尼+80 μg/(kg·min)丙泊酚,观察组给予0.15 μg/(kg·min)舒芬太尼+80 μg/(kg·min)丙泊酚,比较2组患者麻醉前(T1)、气管插管即刻(T2)、切皮即刻(T3)和拔除气管导管即刻(T4)血流动力学、苏醒时间、气管拔管时间、术中知晓情况和视觉模拟评分(VAS),记录并观察2组患者的不良反应发生情况.结果 2组患者均无术中知晓,术毕对照组患者苏醒时间[(316±28) min明显]长于观察组[(276±24) min](P＜0.01).观察组和对照组气管拔管时间分别为(383±22) min、(506±21) min,组间差异有统计学意义(P＜0.01).观察组不良反应发生率为71％ (2/28),明显低于对照组[32.1％ (9/28)].结论 小剂量[0.15 μg/(kg·min)]舒芬太尼配合丙泊酚对老年患者的麻醉镇痛安全、有效,可减少不良反应.
目的 觀察不同濃度舒芬太尼複閤丙泊酚對老年胸腹部手術患者的臨床痳醉效果.方法 選取56例行胸腹部手術的老年患者完全隨機分為觀察組和對照組,各28例.對照組給予0.3μg/(kg·min)舒芬太尼+80 μg/(kg·min)丙泊酚,觀察組給予0.15 μg/(kg·min)舒芬太尼+80 μg/(kg·min)丙泊酚,比較2組患者痳醉前(T1)、氣管插管即刻(T2)、切皮即刻(T3)和拔除氣管導管即刻(T4)血流動力學、囌醒時間、氣管拔管時間、術中知曉情況和視覺模擬評分(VAS),記錄併觀察2組患者的不良反應髮生情況.結果 2組患者均無術中知曉,術畢對照組患者囌醒時間[(316±28) min明顯]長于觀察組[(276±24) min](P＜0.01).觀察組和對照組氣管拔管時間分彆為(383±22) min、(506±21) min,組間差異有統計學意義(P＜0.01).觀察組不良反應髮生率為71％ (2/28),明顯低于對照組[32.1％ (9/28)].結論 小劑量[0.15 μg/(kg·min)]舒芬太尼配閤丙泊酚對老年患者的痳醉鎮痛安全、有效,可減少不良反應.
목적 관찰불동농도서분태니복합병박분대노년흉복부수술환자적림상마취효과.방법 선취56례행흉복부수술적노년환자완전수궤분위관찰조화대조조,각28례.대조조급여0.3μg/(kg·min)서분태니+80 μg/(kg·min)병박분,관찰조급여0.15 μg/(kg·min)서분태니+80 μg/(kg·min)병박분,비교2조환자마취전(T1)、기관삽관즉각(T2)、절피즉각(T3)화발제기관도관즉각(T4)혈류동역학、소성시간、기관발관시간、술중지효정황화시각모의평분(VAS),기록병관찰2조환자적불량반응발생정황.결과 2조환자균무술중지효,술필대조조환자소성시간[(316±28) min명현]장우관찰조[(276±24) min](P＜0.01).관찰조화대조조기관발관시간분별위(383±22) min、(506±21) min,조간차이유통계학의의(P＜0.01).관찰조불량반응발생솔위71％ (2/28),명현저우대조조[32.1％ (9/28)].결론 소제량[0.15 μg/(kg·min)]서분태니배합병박분대노년환자적마취진통안전、유효,가감소불량반응.
Objective To evaluate the efficacy and safety of different dose sufentanil combined with propofol for thoracic and abdominal surgery in elderly patients.Methods Fifty-six elderly patients for thoracic and abdominal surgery were randomly divided into two groups (n =28 each):control group [receiving 0.3 ìg/(kg · min)sufentanil +80 μg/(kg · min) propofol] and observation group [receiving 0.15 μg/(kg · min) sufentanil + 80 μg/(kg · min) propofol].The hemodynamics,recovery time,the tracheal extubation time,awareness,visual analogue scale (VAS) score before anesthesia (T1),tracheal intubation (T2),the incision immediately (T3) and extubation instantly (T4) and adverse reactions and the efficacy of the two groups were compared.Results All the patients had no awareness during operation.The recovery time of control group and observation group were (506 ±21)min,(316 ±28)min,and the tracheal extubation time of them were (383 ±22) min,(276±24) min,with the statistical difference (P ＜ 0.05).The rate of adverse reactions of the control group was 32.1％ (9/28),which was higher than that in observation group (7.1％,2/28) (P ＜ 0.05).Conclusion Small dose sufentanil [0.15 μg/(kg · min)] combined with propofol for thoracic and abdominal surgery in elderly patients is effective which can reduce the adverse reactions.
