中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
4期
549-551
,共3页
惊厥%新生儿%病因
驚厥%新生兒%病因
량궐%신생인%병인
Seizure%Neonate%Etiology
目的 探讨本院2001-2010年新生儿惊厥的病因构成及其变化趋势,便于今后针对性地预防和治疗.方法 2001年1月1日至2010年12月31日本院新生儿重症监护室共收治新生儿惊厥患儿58例,其中2001年1月1日至2005年12月31日第一阶段共28例,2006年1月1日至2010年12月31日第二阶段共30例.回顾性分析新生儿惊厥的病因构成及其变化趋势.应用SPSS 13.0软件,应用x2检验对结果进行分析.结果 ①惊厥类型以微小型最多[27例(46.6%)],其次为多灶性阵挛型[16例(27.6%)].②58例中,新生儿缺氧缺血性脑病和颅内出血29例(50.0%),糖和电解质紊乱16例(27.6%),感染性疾病7例(12.1%),遗传代谢病2例(3.4%),其他4例(6.9%).③2个阶段的病因构成比较一致的是,新生儿惊厥的首要病因均为新生儿缺氧缺血性脑病和颅内出血,其次为糖和电解质紊乱.④第二阶段的病因构成与第一阶段比较,感染性疾病所占比例明显下降[3.3% (1/30)比21.4% (6/28),x2=4.469,P<0.05];第二阶段糖和电解质紊乱所占比例升高,但差异无统计学意义;遗传代谢病所占比例明显升高,但因例数较少未能行统计学分析.结论 新生儿惊厥的病因构成中以新生儿缺氧缺血性脑病和颅内出血为首要原因,对于有围产期窒息史的新生儿,应严密监护,及时发现惊厥.
目的 探討本院2001-2010年新生兒驚厥的病因構成及其變化趨勢,便于今後針對性地預防和治療.方法 2001年1月1日至2010年12月31日本院新生兒重癥鑑護室共收治新生兒驚厥患兒58例,其中2001年1月1日至2005年12月31日第一階段共28例,2006年1月1日至2010年12月31日第二階段共30例.迴顧性分析新生兒驚厥的病因構成及其變化趨勢.應用SPSS 13.0軟件,應用x2檢驗對結果進行分析.結果 ①驚厥類型以微小型最多[27例(46.6%)],其次為多竈性陣攣型[16例(27.6%)].②58例中,新生兒缺氧缺血性腦病和顱內齣血29例(50.0%),糖和電解質紊亂16例(27.6%),感染性疾病7例(12.1%),遺傳代謝病2例(3.4%),其他4例(6.9%).③2箇階段的病因構成比較一緻的是,新生兒驚厥的首要病因均為新生兒缺氧缺血性腦病和顱內齣血,其次為糖和電解質紊亂.④第二階段的病因構成與第一階段比較,感染性疾病所佔比例明顯下降[3.3% (1/30)比21.4% (6/28),x2=4.469,P<0.05];第二階段糖和電解質紊亂所佔比例升高,但差異無統計學意義;遺傳代謝病所佔比例明顯升高,但因例數較少未能行統計學分析.結論 新生兒驚厥的病因構成中以新生兒缺氧缺血性腦病和顱內齣血為首要原因,對于有圍產期窒息史的新生兒,應嚴密鑑護,及時髮現驚厥.
목적 탐토본원2001-2010년신생인량궐적병인구성급기변화추세,편우금후침대성지예방화치료.방법 2001년1월1일지2010년12월31일본원신생인중증감호실공수치신생인량궐환인58례,기중2001년1월1일지2005년12월31일제일계단공28례,2006년1월1일지2010년12월31일제이계단공30례.회고성분석신생인량궐적병인구성급기변화추세.응용SPSS 13.0연건,응용x2검험대결과진행분석.결과 ①량궐류형이미소형최다[27례(46.6%)],기차위다조성진련형[16례(27.6%)].②58례중,신생인결양결혈성뇌병화로내출혈29례(50.0%),당화전해질문란16례(27.6%),감염성질병7례(12.1%),유전대사병2례(3.4%),기타4례(6.9%).③2개계단적병인구성비교일치적시,신생인량궐적수요병인균위신생인결양결혈성뇌병화로내출혈,기차위당화전해질문란.④제이계단적병인구성여제일계단비교,감염성질병소점비례명현하강[3.3% (1/30)비21.4% (6/28),x2=4.469,P<0.05];제이계단당화전해질문란소점비례승고,단차이무통계학의의;유전대사병소점비례명현승고,단인례수교소미능행통계학분석.결론 신생인량궐적병인구성중이신생인결양결혈성뇌병화로내출혈위수요원인,대우유위산기질식사적신생인,응엄밀감호,급시발현량궐.
Objective To explore the cause and change trend of neonatal seizures in our hospital so as to prevent and treat effectively.Methods Fifty-eight newborns with neonatal seizures were admitted in NICU of our hospital from Jan.1,2001 to Dec.31,2010.Among them,28 newborns were born from Jan.1,2001 to Dec.31,2005,and 30 newborns were delivered from Jan.1,2006 to Dec.31,2010.The cause and change trend of neonatal seizures were analyzed.Results ①Subtle seizure was the most type in the study (46.6%),followed by multifocal clonic seizure (27.6%).②Twenty-nine babies had neonatal hypoxic-ischemic encephalopathy or intracranial hemorrhage (50.0%) and sixteen babies had sugar and electrolyte imbalance (27.6%) and seven babies had infectious diseases (12.1%) and 2 babies had inherited metabolic disorder (3.4%).③The leading causes of neonatal seizures were all neonatal hypoxic-ischemic encephalopathy and intracranial hemorrhage in the two phases.The second cause was sugar and electrolyte imbalance.④Neonatal seizures caused by infectious diseases decreased from 21.4% in the first phase to 3.3 % in the second phase (x2 =4.469,P < 0.05) ; seizures caused by sugar and electrolyte imbalance increased from 21.4% in the first phase to 33.3% in the second phase,but had no statistical significance (x2 =1.027,P > 0.05).Conclusions The main cause of neonatal seizures in our hospital is neonatal hypoxic-ischemic encephalopathy and intracranial hemorrhage.Newborns with perinatal asphyxia should be closely observed,if necessary,monitored with video-electroencephalogram,for early detection of seizures.