中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
6期
788-790
,共3页
椎-基底动脉供血不足%眩晕%长春西汀
椎-基底動脈供血不足%眩暈%長春西汀
추-기저동맥공혈불족%현훈%장춘서정
Vertebral-basilar artery insufficiency%Dizziness%Vinpocetine
目的 观察注射用长春西汀治疗椎-基底动脉供血不足性眩晕的疗效.方法 将100例椎基底动脉供血不足性眩晕患者完全随机分为观察组和对照组,各50例.观察组患者给予5％葡萄糖或0.9％氯化钠注射液500 ml加长春西汀注射液30 mg,1次/d静脉滴注.对照组患者给予5％葡萄糖或0.9％氯化钠注射液250 ml加丹参注射液20ml,1次/d静脉滴注.疗程均为10 d.观察患者治疗前后的临床表现、治愈好转情况及左椎动脉、右椎动脉及基底动脉平均血液速度变化.结果 观察组显效44例、有效5例,总有效率98.3％,对照组显效24例、有效20例,总有效率90.0％,2组比较差异有统计学意义(P＜0.05)；观察组和对照组左椎动脉、右椎动脉及基底动脉平均血液速度与治疗前比均有不同程度提高[观察组:(26±8)m/s比(23±7) m/s,(27±7) m/s比(24±7) m/s,(26±8)m/s比(23 ±7) m/s,对照组:(27±8)m/s比(24±7)m/s,(27 ±7)m/s比(24 ±6) m/s,(27±8) m/s比(26±8)m/s] (P＜0.05),但2组治疗后左椎动脉、右椎动脉及基底动脉平均血液速度比较差异无统计学意义(P＞0.05).结论 注射用长春西汀治疗椎基底动脉供血不足性眩晕,疗效显著.
目的 觀察註射用長春西汀治療椎-基底動脈供血不足性眩暈的療效.方法 將100例椎基底動脈供血不足性眩暈患者完全隨機分為觀察組和對照組,各50例.觀察組患者給予5％葡萄糖或0.9％氯化鈉註射液500 ml加長春西汀註射液30 mg,1次/d靜脈滴註.對照組患者給予5％葡萄糖或0.9％氯化鈉註射液250 ml加丹參註射液20ml,1次/d靜脈滴註.療程均為10 d.觀察患者治療前後的臨床錶現、治愈好轉情況及左椎動脈、右椎動脈及基底動脈平均血液速度變化.結果 觀察組顯效44例、有效5例,總有效率98.3％,對照組顯效24例、有效20例,總有效率90.0％,2組比較差異有統計學意義(P＜0.05)；觀察組和對照組左椎動脈、右椎動脈及基底動脈平均血液速度與治療前比均有不同程度提高[觀察組:(26±8)m/s比(23±7) m/s,(27±7) m/s比(24±7) m/s,(26±8)m/s比(23 ±7) m/s,對照組:(27±8)m/s比(24±7)m/s,(27 ±7)m/s比(24 ±6) m/s,(27±8) m/s比(26±8)m/s] (P＜0.05),但2組治療後左椎動脈、右椎動脈及基底動脈平均血液速度比較差異無統計學意義(P＞0.05).結論 註射用長春西汀治療椎基底動脈供血不足性眩暈,療效顯著.
목적 관찰주사용장춘서정치료추-기저동맥공혈불족성현훈적료효.방법 장100례추기저동맥공혈불족성현훈환자완전수궤분위관찰조화대조조,각50례.관찰조환자급여5％포도당혹0.9％록화납주사액500 ml가장춘서정주사액30 mg,1차/d정맥적주.대조조환자급여5％포도당혹0.9％록화납주사액250 ml가단삼주사액20ml,1차/d정맥적주.료정균위10 d.관찰환자치료전후적림상표현、치유호전정황급좌추동맥、우추동맥급기저동맥평균혈액속도변화.결과 관찰조현효44례、유효5례,총유효솔98.3％,대조조현효24례、유효20례,총유효솔90.0％,2조비교차이유통계학의의(P＜0.05)；관찰조화대조조좌추동맥、우추동맥급기저동맥평균혈액속도여치료전비균유불동정도제고[관찰조:(26±8)m/s비(23±7) m/s,(27±7) m/s비(24±7) m/s,(26±8)m/s비(23 ±7) m/s,대조조:(27±8)m/s비(24±7)m/s,(27 ±7)m/s비(24 ±6) m/s,(27±8) m/s비(26±8)m/s] (P＜0.05),단2조치료후좌추동맥、우추동맥급기저동맥평균혈액속도비교차이무통계학의의(P＞0.05).결론 주사용장춘서정치료추기저동맥공혈불족성현훈,료효현저.
Objective To observe and assess the efficacy of intravenous vinpocetine treating vertebrobasilar insufficiency-associated vertigo.Methods One hundred patients were randomly divided into observation group and control group with 50 patients in each group.Patients in observing group were intravenous injected with 30 mg vinpocetine in 500 ml 5％ glucose or 0.9％ sodium chloride once a day for 10 days,while the control group accepted injection of 20 ml salvia in 250 ml 5％ glucose or 0.9％ sodium chloride with the same frequency in the same period.Clinical manifestations and vertebral-basilar artery blood flow changes were evaluated after treatment.Results The treatment was markedly effective in 44 cases,effective in 5 cases and 1 ineffetive case in observation group; the total effective rate was 98.3％.In the control group,there were 24 markedly effective,20 effective and 6 ineffetive cases.The total effective rate was 90.0％.The total effective rate was statistically different between the two groups.The left and right vertebral artery average blood speed was improved after treatment in both groups (P ＜ 0.05).Conclusion Intravenous injection of vinpocetine as a treatment of vertebrobasilar insufficiency-associated vertigo has significant effects.
