中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
10期
1396-1397
,共2页
肾损伤%百令胶囊%呼吸衰竭
腎損傷%百令膠囊%呼吸衰竭
신손상%백령효낭%호흡쇠갈
Renal injury%Bailing capsule%Respiratory failure
目的 探讨百令胶囊预防呼吸衰竭患者肾损伤的疗效.方法 采用随机数字表法将172例呼吸衰竭患者随机分成试验组(87例)和对照组(85例).试验组给予百令胶囊(每日1 g,每天3次)预防治疗,对照组仅予常规治疗.比较2组血尿、蛋白尿及急性肾损伤(AKI)发生率、住院时间和住院费用的差别.结果 ①试验组肾损伤总发生率、血尿、蛋白尿及AKI发生率均明显低于对照组[23.0％ (20/87)比38.8％(33/85),8.0％(7/87)比18.8％ (16/85),19.5％ (17/87)比34.1％(29/85),13.8％(12/87)比27.1％(23/85)],差异有统计学意义(P＜0.05)；②试验组平均住院时间和平均住院费用均显著低于对照组[(15.1±1.1)d比(19.2 ±2.2)d,(1.8±0.9)万元比(2.1±1.0)万元],差异均有统计学意义(P＜0.05或P＜0.01).结论 百令胶囊可有效预防呼吸衰竭患者肾损伤.
目的 探討百令膠囊預防呼吸衰竭患者腎損傷的療效.方法 採用隨機數字錶法將172例呼吸衰竭患者隨機分成試驗組(87例)和對照組(85例).試驗組給予百令膠囊(每日1 g,每天3次)預防治療,對照組僅予常規治療.比較2組血尿、蛋白尿及急性腎損傷(AKI)髮生率、住院時間和住院費用的差彆.結果 ①試驗組腎損傷總髮生率、血尿、蛋白尿及AKI髮生率均明顯低于對照組[23.0％ (20/87)比38.8％(33/85),8.0％(7/87)比18.8％ (16/85),19.5％ (17/87)比34.1％(29/85),13.8％(12/87)比27.1％(23/85)],差異有統計學意義(P＜0.05)；②試驗組平均住院時間和平均住院費用均顯著低于對照組[(15.1±1.1)d比(19.2 ±2.2)d,(1.8±0.9)萬元比(2.1±1.0)萬元],差異均有統計學意義(P＜0.05或P＜0.01).結論 百令膠囊可有效預防呼吸衰竭患者腎損傷.
목적 탐토백령효낭예방호흡쇠갈환자신손상적료효.방법 채용수궤수자표법장172례호흡쇠갈환자수궤분성시험조(87례)화대조조(85례).시험조급여백령효낭(매일1 g,매천3차)예방치료,대조조부여상규치료.비교2조혈뇨、단백뇨급급성신손상(AKI)발생솔、주원시간화주원비용적차별.결과 ①시험조신손상총발생솔、혈뇨、단백뇨급AKI발생솔균명현저우대조조[23.0％ (20/87)비38.8％(33/85),8.0％(7/87)비18.8％ (16/85),19.5％ (17/87)비34.1％(29/85),13.8％(12/87)비27.1％(23/85)],차이유통계학의의(P＜0.05)；②시험조평균주원시간화평균주원비용균현저저우대조조[(15.1±1.1)d비(19.2 ±2.2)d,(1.8±0.9)만원비(2.1±1.0)만원],차이균유통계학의의(P＜0.05혹P＜0.01).결론 백령효낭가유효예방호흡쇠갈환자신손상.
Objective To explore the effect of Bailing capsule on the prevention of renal injury in patients with respiratory failure.Methods By simple randomization,the patients were divided into the observation group and the control group.The difference of the incidence of hematuria,proteinuria and acute kidney injury(AKI),hospital stay and hospital costs were compared between the two groups.Results The incidence of hematuria,proteinuria and AKI in the observation group were significandy lower than that in the control group [23.0％ (20/87) vs 38.8％ (33/85),8.0％ (7/87) vs 18.8 ％ (16/85),19.5 ％ (17/87) vs 34.1％ (29/85),13.8 ％ (12/87) vs 27.1％ (23/85)] (P ＜ 0.05) ; The hospital stay and hospital costs in the observation group were significantly lower than that in the control group[(15.1 ±1.1)d vs (19.2 ±2.2)d,(1.8 ±0.9)million yuan vs (2.1 ± 1.0)million yuan] (P ＜ 0.05 or P ＜ 0.01).Conclusion Bailing capsule has a good effect on the prevention of renal injury in patients with respiratory failure.
