中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
11期
1521-1523
,共3页
崔清华%孙秀芹%包柄楠%陶红%赵怡%周迎生
崔清華%孫秀芹%包柄楠%陶紅%趙怡%週迎生
최청화%손수근%포병남%도홍%조이%주영생
冠心病%颈动脉狭窄%多支病变
冠心病%頸動脈狹窄%多支病變
관심병%경동맥협착%다지병변
Coronary heart disease%Carotid artery stenosis%Multivessel lesion
目的 分析冠心病合并颈动脉狭窄患者血管病变相关因素.方法 收集北京安贞医院2010 年1-12月行冠状动脉造影并确诊为冠心病住院患者329例,依据颈动脉超声结果分为颈动脉狭窄＜50％组(272例)和颈动脉狭窄≥50％组(57例),统计分析2组患者血管病变及相关因素.结果 ①冠心病患者中颈动脉狭窄≥50％的患病率为17.3％ (57/329),颈动脉狭窄≥70％的患病率为3.6％ (12/329).②合并颈动脉狭窄≥50％的冠心病患者中冠状动脉多支病变比例为66.7％(38/57),明显高于颈动脉狭窄＜50％组[52.2％ (142/272)] (P ＜0.05).③2组间年龄、BMI、脉压差、血脂水平、空腹血糖、糖化血红蛋白(HbA1c)、血尿酸水平比较,差异无统计学意义(P＞0.05).④多支病变与冠心病合并颈动脉狭窄≥50％(r =0.01,P =0.046)、2型糖尿病(r=0.11,P=0.046)有相关性.结论 冠状动脉多支病变与颈动脉狭窄≥50％有相关性.
目的 分析冠心病閤併頸動脈狹窄患者血管病變相關因素.方法 收集北京安貞醫院2010 年1-12月行冠狀動脈造影併確診為冠心病住院患者329例,依據頸動脈超聲結果分為頸動脈狹窄＜50％組(272例)和頸動脈狹窄≥50％組(57例),統計分析2組患者血管病變及相關因素.結果 ①冠心病患者中頸動脈狹窄≥50％的患病率為17.3％ (57/329),頸動脈狹窄≥70％的患病率為3.6％ (12/329).②閤併頸動脈狹窄≥50％的冠心病患者中冠狀動脈多支病變比例為66.7％(38/57),明顯高于頸動脈狹窄＜50％組[52.2％ (142/272)] (P ＜0.05).③2組間年齡、BMI、脈壓差、血脂水平、空腹血糖、糖化血紅蛋白(HbA1c)、血尿痠水平比較,差異無統計學意義(P＞0.05).④多支病變與冠心病閤併頸動脈狹窄≥50％(r =0.01,P =0.046)、2型糖尿病(r=0.11,P=0.046)有相關性.結論 冠狀動脈多支病變與頸動脈狹窄≥50％有相關性.
목적 분석관심병합병경동맥협착환자혈관병변상관인소.방법 수집북경안정의원2010 년1-12월행관상동맥조영병학진위관심병주원환자329례,의거경동맥초성결과분위경동맥협착＜50％조(272례)화경동맥협착≥50％조(57례),통계분석2조환자혈관병변급상관인소.결과 ①관심병환자중경동맥협착≥50％적환병솔위17.3％ (57/329),경동맥협착≥70％적환병솔위3.6％ (12/329).②합병경동맥협착≥50％적관심병환자중관상동맥다지병변비례위66.7％(38/57),명현고우경동맥협착＜50％조[52.2％ (142/272)] (P ＜0.05).③2조간년령、BMI、맥압차、혈지수평、공복혈당、당화혈홍단백(HbA1c)、혈뇨산수평비교,차이무통계학의의(P＞0.05).④다지병변여관심병합병경동맥협착≥50％(r =0.01,P =0.046)、2형당뇨병(r=0.11,P=0.046)유상관성.결론 관상동맥다지병변여경동맥협착≥50％유상관성.
Objective To analyze the related factors of vascular lesions in coronary heart disease patients with carotid artery stenosis.Methods Totally 329 hospitalized patients with coronary artery disease confirmed by coronary angiography were retrospectively analyzed from January to December in 2010.All the participants underwent carotid ultrasonography.According to the carotid ultrasonography results,all the participants were divided into two groups inoluding carotid stenosis ＜ 50％ (272 cases) and carotid stenosis ≥ 50％ (57 cases).Vascular lesions and related factors of two groups were statistically analyzed.Results ①The morbidity was 17.3％ (57/329) in carotid stenosis≥50％ group and 3.6％ (12/329) in carotid stenosis ≥70％.②The ratio of coronary multivessel lesion was 66.7 ％ (38/57) in carotid stenosis ≥ 50％ group,which was higher than that in the control group [52.2％(142/272)] (P ＜0.05).③There was no significant difference between the two groups in age,body mass index (BMI),pulse pressure,blood lipid levels,fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c) and blood uric acid (UA) levels (P ＞ 0.05).④ Coronary multivessel lesion was associated with carotid stenosis ≥ 50％(r =0.11,P =0.046) and type 2 diabets (r =0.11,P =0.046).Conclusion The ratio of coronary multivessel lesion in coronary heart disease patients with carotid artery stenosis ≥ 50％ is obviously higher than that in patients with carotid artery stenosis ＜ 50％ ; coronary multivessel lesion is a risk factor of carotid stenosis ≥50％.
