CAJ | 학술논문

目的评价血栓抽吸导管在治疗冠状动脉支架血栓时的疗效.方法连续入选北京安贞医院2008年10月至2012年10月应用ZEEK血栓抽吸导管治疗的支架血栓患者32例,回顾性分析ZEEK血栓抽吸导管通过支架血栓病变的能力；抽吸后血栓改变情况；抽吸后病变血管远端血流恢复情况；抽吸后心肌呈色分级情况；抽吸后新发冠状动脉夹层情况；住院期间死亡及再发支架血栓等主要临床事件情况.结果 32例患者中有30例(93.8％)血栓抽吸导管通过支架血栓病变；抽吸后血栓明显减少；抽吸后病变血管远端血流达到心肌梗死溶栓试验血流分级(TIMI)3级的例数为25例(78.1％),较抽吸前(2例)增加23例；抽吸后心肌呈色达到3级的例数为21例(65.6％),较抽吸前(2例)增加19例；抽吸后无新发冠状动脉夹层并发症出现；住院期间有3例(9.4％)患者死亡,有2例(6.2％)再次出现支架血栓.结论应用ZEEK血栓抽吸导管治疗支架血栓安全、有效.
목적 평개혈전추흡도관재치료관상동맥지가혈전시적료효.방법 련속입선북경안정의원2008년10월지2012년10월응용ZEEK혈전추흡도관치료적지가혈전환자32례,회고성분석ZEEK혈전추흡도관통과지가혈전병변적능력；추흡후혈전개변정황；추흡후병변혈관원단혈류회복정황；추흡후심기정색분급정황；추흡후신발관상동맥협층정황；주원기간사망급재발지가혈전등주요림상사건정황.결과 32례환자중유30례(93.8％)혈전추흡도관통과지가혈전병변；추흡후혈전명현감소；추흡후병변혈관원단혈류체도심기경사용전시험혈류분급(TIMI)3급적례수위25례(78.1％),교추흡전(2례)증가23례；추흡후심기정색체도3급적례수위21례(65.6％),교추흡전(2례)증가19례；추흡후무신발관상동맥협층병발증출현；주원기간유3례(9.4％)환자사망,유2례(6.2％)재차출현지가혈전.결론 응용ZEEK혈전추흡도관치료지가혈전안전、유효.
Objective To evaluate the application of thrombus aspiration catheter in treatment of coronary stent thrombosis.Methods From October 2008 to October 2012,32 consecutive patients with stent thrombosis who received ZEEK thrombus aspiration catheter were involved in a single center retrospective analysis.Primary endpoints were device pushability and trackability,myocardial blush grade (MBG),thrombolysis in myocardial infarction (TIMI) flow grade and aspiration efficacy as indicated by size distribution of aspirated thrombi.Cardiac death and recurrent stent thrombosis as major adverse cardiac events (MACE).Results ZEEK thrombus aspiration catheter was delivered through culprit lesions successfully in 30 patients (93.8％).TIMI reached 3 degrees in 25 patients (78.1％) and increased in 23 patients after thrombus aspiration; the MBG reached 3 degrees in 21 patients(65.6％)and increased with 19 patients after thrombus aspiration;there was no new coronary artery dissection in the culprit lesions.There were 3 (9.4％)and 2 recurrent stent thrombosis (6.2％)death in hospital.Conclusion Application of ZEEK thrombus aspiration catheter in treatment of stent thrombosis is safe and effective.