CAJ | 학술논문

目的分析不同浓度氯化钠注射液联合沙丁胺醇雾化在感染性细支气管炎治疗中的效果.方法将48例感染性细支气管炎患儿完全随机分为观察组和对照组,每组24例.观察组雾化吸入高渗盐水(10％氯化钠注射液)1ml为0.9％氯化钠注射液1ml+沙丁胺醇2.5 mg,对照组雾化吸入0.9％氯化钠注射液4 ml+沙丁胺醇2.5 mg,均1次/8 h,共3～5d.比较2组临床咳嗽、喘息、肺部体征好转时间.结果观察组病情严重程度缓解时间平均为(1.8±1.2)d；对照组为(3.2±1.8)d.观察组总有效率为91.7％ (22/24),对照组为79.2％ (19/24).观察组疗效明显优于对照组,差异有统计学意义(P＜0.05).结论 10％氯化钠注射液联合沙丁胺醇雾化治疗感染性细支气管安全、有效.
목적 분석불동농도록화납주사액연합사정알순무화재감염성세지기관염치료중적효과.방법 장48례감염성세지기관염환인완전수궤분위관찰조화대조조,매조24례.관찰조무화흡입고삼염수(10％록화납주사액)1ml위0.9％록화납주사액1ml+사정알순2.5 mg,대조조무화흡입0.9％록화납주사액4 ml+사정알순2.5 mg,균1차/8 h,공3～5d.비교2조림상해수、천식、폐부체정호전시간.결과 관찰조병정엄중정도완해시간평균위(1.8±1.2)d；대조조위(3.2±1.8)d.관찰조총유효솔위91.7％ (22/24),대조조위79.2％ (19/24).관찰조료효명현우우대조조,차이유통계학의의(P＜0.05).결론 10％록화납주사액연합사정알순무화치료감염성세지기관안전、유효.
Objective To observe the effect of different concentrations of saline combined with salbutamol in the treatment of infectious bronchiolitis.Methods Forty-eight cases of mild to infectious bronchiolitis were divided into two groups.The infants received inhalation of 2.5 mg (0.5 ml) salbutamol was dissolved in either 4 ml normal (0.9 ％) saline (control group,n =24) or 4 ml hypertonie (10％) saline (observation group,n =24).Patients in each group received 3 treatments every day.Cough,wheezing,pulmonary physical signs and the length of hospital stay were recorded and compared.Results The severity of the disease remission time averaged of the observation group was (1.8 ± 1.2) d; control group was (3.2 ± 1.8) d; the total efficiency of the observation group was 91.7％ (22/24) ; control group was 79.1％ (19/24) ; the observation group was significantly superior to the control group and the difference was statistically significant (P ＜ 0.05).Conclusion Inhalation of hypertonie saline solution and salbutamolis is a safe and effective therapy treating patients with infectious bronchiolitis.