中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
11期
1588-1590
,共3页
食管肿瘤%胸腔镜%腹腔镜
食管腫瘤%胸腔鏡%腹腔鏡
식관종류%흉강경%복강경
Esophageal carcinoma%Thoracoscopy%Laparoscopy
目的 探究电视胸腔镜联合腹腔镜食管癌根治性手术与常规手术术后炎性指标[(肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)和高敏C反应蛋白(hs-CRP)]水平及痰量的差异,评估其对护理的影响.方法 将2011年12月至2012年12月收治的47例食管癌患者按手术方式不同分为联合腔镜组(25例)和常规手术组(22例)；检测并比较2组患者术前和术后血清TNF-α、IL-6及hs-CRP水平,同时测量2组患者术后的痰量.结果 术前血清炎性指标水平2组差异无统计学意义；术后联合腔镜组患者hs-CRP、TNF-α和IL-6水平明显低于常规手术组[分别为(1.96±1.08) mg/L比(2.64±1.12) mg/L,(22±8)ng/L比(28±6) ng/L,(23±12) ng/L比(61±14) ng/L,均P＜0.05]；且痰量明显少于常规手术组[(73±11)ml比(135±11)ml,P＜0.01].结论 胸腹腔镜联合行食管癌根治术术后炎症反应水平较常规手术降低,直接反映为术后痰量明显减少,对降低食管癌术后肺部护理强度有重要意义.
目的 探究電視胸腔鏡聯閤腹腔鏡食管癌根治性手術與常規手術術後炎性指標[(腫瘤壞死因子α(TNF-α)、白細胞介素6(IL-6)和高敏C反應蛋白(hs-CRP)]水平及痰量的差異,評估其對護理的影響.方法 將2011年12月至2012年12月收治的47例食管癌患者按手術方式不同分為聯閤腔鏡組(25例)和常規手術組(22例)；檢測併比較2組患者術前和術後血清TNF-α、IL-6及hs-CRP水平,同時測量2組患者術後的痰量.結果 術前血清炎性指標水平2組差異無統計學意義；術後聯閤腔鏡組患者hs-CRP、TNF-α和IL-6水平明顯低于常規手術組[分彆為(1.96±1.08) mg/L比(2.64±1.12) mg/L,(22±8)ng/L比(28±6) ng/L,(23±12) ng/L比(61±14) ng/L,均P＜0.05]；且痰量明顯少于常規手術組[(73±11)ml比(135±11)ml,P＜0.01].結論 胸腹腔鏡聯閤行食管癌根治術術後炎癥反應水平較常規手術降低,直接反映為術後痰量明顯減少,對降低食管癌術後肺部護理彊度有重要意義.
목적 탐구전시흉강경연합복강경식관암근치성수술여상규수술술후염성지표[(종류배사인자α(TNF-α)、백세포개소6(IL-6)화고민C반응단백(hs-CRP)]수평급담량적차이,평고기대호리적영향.방법 장2011년12월지2012년12월수치적47례식관암환자안수술방식불동분위연합강경조(25례)화상규수술조(22례)；검측병비교2조환자술전화술후혈청TNF-α、IL-6급hs-CRP수평,동시측량2조환자술후적담량.결과 술전혈청염성지표수평2조차이무통계학의의；술후연합강경조환자hs-CRP、TNF-α화IL-6수평명현저우상규수술조[분별위(1.96±1.08) mg/L비(2.64±1.12) mg/L,(22±8)ng/L비(28±6) ng/L,(23±12) ng/L비(61±14) ng/L,균P＜0.05]；차담량명현소우상규수술조[(73±11)ml비(135±11)ml,P＜0.01].결론 흉복강경연합행식관암근치술술후염증반응수평교상규수술강저,직접반영위술후담량명현감소,대강저식관암술후폐부호리강도유중요의의.
Objective To investigate the level of cytokines in laparscopy and video-assisted thoracoscopic surgery (VATS) in radical correction of esophageal carcinoma with the classical surgery.Methods Forty-seven patients with esophageal carcinoma between December 2011 and December 2012 were divided into combined laparoscope group(25 cases; thoracoscopic and laparscopic esophagectomy or laparoscope and video-assisted thoracoscopic surgery) and classical surgery group(22 cases).The levels of tumor necrosis factor alpha (TNF alpha),interleukin 6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) of the two groups in preoperative and postoperative were measured and compared.The volume of sputum after the surgery was recorded.Results No significant difference was found in the postoperative value of hs-CRP,IL-6,TNF-α.Compared to the group of classical surgery,the level of hs-CRP,TNF-α,IL-6 and volume of sputum in the group of video-assisted thoracoscopic surgery were significantly lower after surgery [(1.96 ± 1.08) mg/L vs (2.64 ± 1.12) mg/L,(22 ± 8) ng/L vs (28 ± 6) ng/L,(23 ± 12) ng/L vs (61 ± 14) ng/L,(73 ± 11) ml vs (135 ± 11) ml,P ＜ 0.05 or P ＜ 0.01].Conclusion Combining thoracoscopic and laparscopic esophagectomy can reduce the postoperative inflammation levels and descend the pulmonary care intensity.
