CAJ | 학술논문

目的探讨308 nm准分子激光治疗慢性女阴营养不良症的有效性与安全性.方法选取新疆维吾尔自治区克拉玛依市中心医院门诊就诊的慢性女阴营养不良症患者84例,按就诊顺序随机分为2组.观察组44例,采用308 nm准分子激光局部照射治疗,2次/周；对照组40例,外用盐酸曲安奈德软膏2次/d,使用时软膏薄涂患处,轻轻揉搓2～5 min,4周为1个疗程.2组均治疗4周.观察和分析治疗效果及不良反应.结果观察组总有效率为93.2％ (41/44),对照组总有效率为70.0％(28/40),组间差异有统计学意义x2=7.69,P＜0.05).观察组中有1例患者在加量时出现红斑时间延长、轻微水肿疼痛,未予处理,自行恢复；2例患者出现轻微脱屑.结论 308 nm准分子激光治疗慢性女阴营养不良近期疗效明显,副作用较少.
목적 탐토308 nm준분자격광치료만성녀음영양불량증적유효성여안전성.방법 선취신강유오이자치구극랍마의시중심의원문진취진적만성녀음영양불량증환자84례,안취진순서수궤분위2조.관찰조44례,채용308 nm준분자격광국부조사치료,2차/주；대조조40례,외용염산곡안내덕연고2차/d,사용시연고박도환처,경경유차2～5 min,4주위1개료정.2조균치료4주.관찰화분석치료효과급불량반응.결과 관찰조총유효솔위93.2％ (41/44),대조조총유효솔위70.0％(28/40),조간차이유통계학의의x2=7.69,P＜0.05).관찰조중유1례환자재가량시출현홍반시간연장、경미수종동통,미여처리,자행회복；2례환자출현경미탈설.결론 308 nm준분자격광치료만성녀음영양불량근기료효명현,부작용교소.
Objective To investigate the efficacy and safety of 308 nm excimer laser in the treatment of chronic vulvar dystrophy.Methods Totally 84 patients with chronic vulvar dystrophy were randomly divided into 2 groups.44 patients in the observation group were treated with 308 nm excimer laser twice a week; the control group (40 cases) was treated with triamcinolone acetonide twice every day.The follow-up was 4 weeks.The clinical response to therapy and adverse effects was recorded.Results The total effective rate was 93.2％ (4/44) in the observation group.The total effective rate was 70.0％ (28/40) in the control group.The comparison in two groups showed significant differences (x2 =7.69,P ＜ 0.05).The side effect was only erythema which was well tolerated with a low incidence during treatment.Conclusion The treatment of chronic vulvar dystrophy with 308 nm excimer laser shows good efficacy in short time with little adverse reactions.