中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
z1期
5-6
,共2页
胡令英%王丽%孙晓芳%徐芳芳
鬍令英%王麗%孫曉芳%徐芳芳
호령영%왕려%손효방%서방방
呼吸窘迫综合征%氧气驱动%肺表面活性物质
呼吸窘迫綜閤徵%氧氣驅動%肺錶麵活性物質
호흡군박종합정%양기구동%폐표면활성물질
Respiratory distress syndrome%Aerosol inhalating%Pulmonary surfactant
目的 探讨氧气驱动吸入肺表面活性物质防治呼吸窘迫综合征的疗效.方法 将52例新生儿呼吸窘迫综合征患儿随机分为氧气驱动吸入组和气管插管组,各26例,分别通过氧气驱动吸入和气管插管滴注肺表面活性物质,比较治疗前及治疗6、24h后2组的临床表现,血气分析及并发症发生情况.结果 应用肺表面活性物质治疗6h和24h后,氧气驱动吸入组与气管插管组血气分析比较,差异均无统计学意义(均P＞0.05).氧气驱动吸入组肺部感染1例(3.8％),气胸、肺不张0例；气管插管组肺部感染8例(30.8％),气胸2例(7.7％),肺不张1例(3.8％).2组肺部感染发生率比较,差异有统计学意义(x2=6.58,P＜0.05).结论 氧气驱动吸入能有效改善呼吸窘迫综合征患儿的肺通气和换气功能,改善临床表现,减少并发症.
目的 探討氧氣驅動吸入肺錶麵活性物質防治呼吸窘迫綜閤徵的療效.方法 將52例新生兒呼吸窘迫綜閤徵患兒隨機分為氧氣驅動吸入組和氣管插管組,各26例,分彆通過氧氣驅動吸入和氣管插管滴註肺錶麵活性物質,比較治療前及治療6、24h後2組的臨床錶現,血氣分析及併髮癥髮生情況.結果 應用肺錶麵活性物質治療6h和24h後,氧氣驅動吸入組與氣管插管組血氣分析比較,差異均無統計學意義(均P＞0.05).氧氣驅動吸入組肺部感染1例(3.8％),氣胸、肺不張0例；氣管插管組肺部感染8例(30.8％),氣胸2例(7.7％),肺不張1例(3.8％).2組肺部感染髮生率比較,差異有統計學意義(x2=6.58,P＜0.05).結論 氧氣驅動吸入能有效改善呼吸窘迫綜閤徵患兒的肺通氣和換氣功能,改善臨床錶現,減少併髮癥.
목적 탐토양기구동흡입폐표면활성물질방치호흡군박종합정적료효.방법 장52례신생인호흡군박종합정환인수궤분위양기구동흡입조화기관삽관조,각26례,분별통과양기구동흡입화기관삽관적주폐표면활성물질,비교치료전급치료6、24h후2조적림상표현,혈기분석급병발증발생정황.결과 응용폐표면활성물질치료6h화24h후,양기구동흡입조여기관삽관조혈기분석비교,차이균무통계학의의(균P＞0.05).양기구동흡입조폐부감염1례(3.8％),기흉、폐불장0례；기관삽관조폐부감염8례(30.8％),기흉2례(7.7％),폐불장1례(3.8％).2조폐부감염발생솔비교,차이유통계학의의(x2=6.58,P＜0.05).결론 양기구동흡입능유효개선호흡군박종합정환인적폐통기화환기공능,개선림상표현,감소병발증.
Objective To observe the effect of aerosol inhalating the pulmonary surfactant in treatment of respiratory distress syndrome.Methods Fifty-two cases of neonatal respiratory distress syndrome were randomly divided into inhalation group and intubation group,each group had 26 cases.Inhalation group were given lung surface active substances under oxygen driving,intubation group used endotracheal intubation drip lung surface active material.The clinical manifestation,blood gas analysis and its complications of two groups were compared before and 6,24 h after treatment.Results Clinical performance improved significantly after 6 hours from applicating pulmonary surfactant.The results of inhalation of children with blood gas analysis were same with the results of intubation(P ＞ 0.05).Clinical performances were also returned to normal after 24 hours.The results of inhalation of children with blood gas analysis were the same with the results of intubation(P ＞ 0.05).One case(3.8％) had lung infection in children who inhaled pulmonary surfactant.Nobady had pneumothorax and atelectasis in children who inhaled pulmonary surfactant.Eight cases (30.8％) had lung infection in children who instiled pulmonary surfactant.Two cases (7.7％) had pneumothorax and 1 case(3.8％) had aelectasis in children who were injected from intubation the pulmonary surfactant.Conclusions Aerosol inhalating pulmonary surfactant has markedly effect in the treatment of respiratory distress syndrome,it can effectively improve lung function and reduce complications.
