中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
2期
185-188
,共4页
脑挫裂伤%血栓通注射液%临床疗效
腦挫裂傷%血栓通註射液%臨床療效
뇌좌렬상%혈전통주사액%림상료효
Cerebral contusion%Xueshuantong injection%Clinical efficacy
目的 观察血栓通注射液治疗额颞叶脑挫裂伤伴血肿的临床效果.方法 将轻中度额颞叶脑挫裂伤伴血肿形成的94例患者按随机数字表分为观察组及对照组,每组47例.对照组采用常规治疗;观察组在常规治疗基础上加用血栓通注射液0.5g静脉滴注,1次/d,连用14 d.治疗14 d后,评定临床疗效、神经功能及生活质量(Barthel指数).结果 治疗14 d后,观察组总有效率明显高于对照组[78.7％(37/47)比59.6％ (28/47)],差异有统计学意义(P＜0.05);观察组和对照组神经功能缺损积分均低于治疗前[(13±6)分比(25±6)分,(16±6)分比(24±5)分,均P＜0.05],且观察组明显低于对照组(P＜0.05);观察组和对照组治疗14 d后Barthel评分均较治疗前改善[(73±18)分比(34±18)分,(61±17)分比(36±18)分],差异有统计学意义(P＜0.05),但观察组明显高于对照组(P＜0.05);治疗14 d后,观察组和对照组血肿较治疗前明显缩小[(1.4±0.9)ml比(18.1±9.2)ml,(2.9±1.4)ml比(16.9±9.8)ml],差异有统计学意义(P＜0.05),但观察组血肿体积明显少于对照组(P＜0.05).结论 血栓通注射液治疗脑挫裂伤伴血肿较内科常规方法有更好的临床疗效,能明显促进血肿吸收,促进神经功能恢复,改善日常生活活动能力,提高临床疗效.
目的 觀察血栓通註射液治療額顳葉腦挫裂傷伴血腫的臨床效果.方法 將輕中度額顳葉腦挫裂傷伴血腫形成的94例患者按隨機數字錶分為觀察組及對照組,每組47例.對照組採用常規治療;觀察組在常規治療基礎上加用血栓通註射液0.5g靜脈滴註,1次/d,連用14 d.治療14 d後,評定臨床療效、神經功能及生活質量(Barthel指數).結果 治療14 d後,觀察組總有效率明顯高于對照組[78.7％(37/47)比59.6％ (28/47)],差異有統計學意義(P＜0.05);觀察組和對照組神經功能缺損積分均低于治療前[(13±6)分比(25±6)分,(16±6)分比(24±5)分,均P＜0.05],且觀察組明顯低于對照組(P＜0.05);觀察組和對照組治療14 d後Barthel評分均較治療前改善[(73±18)分比(34±18)分,(61±17)分比(36±18)分],差異有統計學意義(P＜0.05),但觀察組明顯高于對照組(P＜0.05);治療14 d後,觀察組和對照組血腫較治療前明顯縮小[(1.4±0.9)ml比(18.1±9.2)ml,(2.9±1.4)ml比(16.9±9.8)ml],差異有統計學意義(P＜0.05),但觀察組血腫體積明顯少于對照組(P＜0.05).結論 血栓通註射液治療腦挫裂傷伴血腫較內科常規方法有更好的臨床療效,能明顯促進血腫吸收,促進神經功能恢複,改善日常生活活動能力,提高臨床療效.
목적 관찰혈전통주사액치료액섭협뇌좌렬상반혈종적림상효과.방법 장경중도액섭협뇌좌렬상반혈종형성적94례환자안수궤수자표분위관찰조급대조조,매조47례.대조조채용상규치료;관찰조재상규치료기출상가용혈전통주사액0.5g정맥적주,1차/d,련용14 d.치료14 d후,평정림상료효、신경공능급생활질량(Barthel지수).결과 치료14 d후,관찰조총유효솔명현고우대조조[78.7％(37/47)비59.6％ (28/47)],차이유통계학의의(P＜0.05);관찰조화대조조신경공능결손적분균저우치료전[(13±6)분비(25±6)분,(16±6)분비(24±5)분,균P＜0.05],차관찰조명현저우대조조(P＜0.05);관찰조화대조조치료14 d후Barthel평분균교치료전개선[(73±18)분비(34±18)분,(61±17)분비(36±18)분],차이유통계학의의(P＜0.05),단관찰조명현고우대조조(P＜0.05);치료14 d후,관찰조화대조조혈종교치료전명현축소[(1.4±0.9)ml비(18.1±9.2)ml,(2.9±1.4)ml비(16.9±9.8)ml],차이유통계학의의(P＜0.05),단관찰조혈종체적명현소우대조조(P＜0.05).결론 혈전통주사액치료뇌좌렬상반혈종교내과상규방법유경호적림상료효,능명현촉진혈종흡수,촉진신경공능회복,개선일상생활활동능력,제고림상료효.
Objective To observe the clinical efficacy of Xueshuantong injection in the treatment of frontotemporal lobe cerebral contusion.Methods All 94 patients were randomly divided into control group and observation group; the control group was treated with conventional therapy and the observation group was added the Xueshuantong injection; the observation time was three weeks.The clinical efficacy,neurological deficit and the activities of daily living were assessed.Results After treatment of 14 days,the total effective rate in observation group was higher than that in control group [78.7％ (37/47) vs 59.6％ (28/47),P ＜ 0.05] ; the scores of neurological deficit in observation group and control group were less than those before treatment [(13 ±6)scores vs (25 ± 6) scores,(16 ± 6) scores vs (24 ± 5) scores,all P ＜ 0.05],and the scores of observation group were lower than those of control group (P ＜ 0.05) ; the scores of Bathel scores in observation group and control group were higher than those before treatment [(73 ± 18)scores vs (34 ± 18)scores,(61 ± 17)scores vs (36 ± 18)scores,all P ＜0.05],and the scores of observation group were more than those of control group (P ＜ 0.05) ; the volume of hematoma in observation group and control group was less than that before treatment [(1.4 ± 0.9) ml vs (18.1 ±9.2) ml,(2.9 ± 1.4) ml vs (16.9 ± 9.8) ml],and the volume of observation group was less than that of control group (P ＜ 0.05).Conclusion Xueshuantong injection in the treatment of cerebral contusion can significantly promote the absorption of hematoma and the recovery of neurological function.
