CAJ | 학술논문

目的探讨乳晕下亚甲蓝法前哨淋巴结活检术(SLNB)用于乳腺癌手术治疗的可行性及其对腋窝淋巴结分期的预测情况.方法回顾性分析2009年7月至2012年7月北京丰台医院普外科所实施的60例行SLNB患者的病历资料.60例患者均于患侧乳晕皮下注射1%亚甲蓝2 ml(分4象限注射,每点注射0.5 ml),并行腋窝淋巴结清扫.结果 60例乳腺癌术中行SLNB病例中57例发现紧急的SLNB,检出率为95.0%.病理检查者发现28例腋窝淋巴结有转移,32例无转移.前哨淋巴结与腋窝淋巴结完全符合者54例,保受阴性者3例.SLNB的准确率为94.7%(54/57),灵敏度为89.3%(25/28),假阴性率为10.7%(3/28).前哨淋巴结检出率与年龄、肿瘤位置、病理类型、雌激素受体无关(P>0.05).结论乳晕下亚甲蓝法SLNB能准确地预测乳腺癌腋窝淋巴结的转移状态.
목적 탐토유훈하아갑람법전초림파결활검술(SLNB)용우유선암수술치료적가행성급기대액와림파결분기적예측정황.방법 회고성분석2009년7월지2012년7월북경봉태의원보외과소실시적60례행SLNB환자적병력자료.60례환자균우환측유훈피하주사1%아갑람2 ml(분4상한주사,매점주사0.5 ml),병행액와림파결청소.결과 60례유선암술중행SLNB병례중57례발현긴급적SLNB,검출솔위95.0%.병리검사자발현28례액와림파결유전이,32례무전이.전초림파결여액와림파결완전부합자54례,보수음성자3례.SLNB적준학솔위94.7%(54/57),령민도위89.3%(25/28),가음성솔위10.7%(3/28).전초림파결검출솔여년령、종류위치、병리류형、자격소수체무관(P>0.05).결론 유훈하아갑람법SLNB능준학지예측유선암액와림파결적전이상태.
Objective To evaluate the feasibility of sentinel lymph node biopsy(SLNB) by using subareolar injection of methylene blue in breast cancer and predict axillary lymph node staging. Methods A retrospective study was conducted to analyze 60 cases of breast cancer's sentinel lymph node biopsy on the consent of patients in Beijing Fengtai hospital from July 2009 to July 2012. All 60 cases were using methylene blue dye areola injections in subareolar. Axillary lymph node dissection(ALND) in all cases. Results Of 60 cases, 57 patients' sentinel lymph nodes were detected successfully in all 60 cases.Only 3 cases were not detected and 3 periods negative; the detection rate was 95.0%(57/60); the accuracy rate was 94.7%(54/57); the sensitivity was 89.3%(25/28); the false negative rate was 10.7%(3/28). Age, location of tumor, histological type and estrogen receptor status were not associated with intraoperative detection rate of SLN(P>0.05). Conclusion Sentinel lymph node biopsy can accurately predict the axillary lymph nodes of breast cancer.