中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
4期
487-489
,共3页
心力衰竭%重症肺炎%小剂量西地兰%早期干预%婴幼儿
心力衰竭%重癥肺炎%小劑量西地蘭%早期榦預%嬰幼兒
심력쇠갈%중증폐염%소제량서지란%조기간예%영유인
Cardiac failure%Severe pneumonia%Small dose cedilanid%Early intervention%Infant
目的 探讨小剂量西地兰在婴幼儿重症肺炎心力衰竭前期给药的临床意义. 方法 将江苏省泰州市姜堰中医院儿科48例重症肺炎心力衰竭前期患儿按入选单双日分为观察组(23例)和对照组(25例).2组均给予氧疗、监测生命体征、抗炎、抗病毒、止咳平喘、化痰、限制入量等常规综合治疗,观察组加用小剂量西地兰干预治疗观察比较2组患儿的心率及呼吸转正常的时间、住院时间、临床疗效及转旧.结果 观察组心率及呼吸转正常的时间、住院时间与对照组比较[(0.8±0.3)d比(3.8±0.7)d、(1.0±0.5)d比(3.6±0.6)d、(7.1±0.5)d比(8.0±0.4)d],差异均有统计学意义(均P＜0.01) 观察组总有效率为100.0％(23/23),对照组总有效率为56.0％(14/25),2组比较差异有统计学意义(P＜0.05).对照组有7例患儿发展为典型心力衰竭.结论 早期应用小剂量西地兰干预婴幼儿重症肺炎能安全有效地防止心力衰竭的发生.
目的 探討小劑量西地蘭在嬰幼兒重癥肺炎心力衰竭前期給藥的臨床意義. 方法 將江囌省泰州市薑堰中醫院兒科48例重癥肺炎心力衰竭前期患兒按入選單雙日分為觀察組(23例)和對照組(25例).2組均給予氧療、鑑測生命體徵、抗炎、抗病毒、止咳平喘、化痰、限製入量等常規綜閤治療,觀察組加用小劑量西地蘭榦預治療觀察比較2組患兒的心率及呼吸轉正常的時間、住院時間、臨床療效及轉舊.結果 觀察組心率及呼吸轉正常的時間、住院時間與對照組比較[(0.8±0.3)d比(3.8±0.7)d、(1.0±0.5)d比(3.6±0.6)d、(7.1±0.5)d比(8.0±0.4)d],差異均有統計學意義(均P＜0.01) 觀察組總有效率為100.0％(23/23),對照組總有效率為56.0％(14/25),2組比較差異有統計學意義(P＜0.05).對照組有7例患兒髮展為典型心力衰竭.結論 早期應用小劑量西地蘭榦預嬰幼兒重癥肺炎能安全有效地防止心力衰竭的髮生.
목적 탐토소제량서지란재영유인중증폐염심력쇠갈전기급약적림상의의. 방법 장강소성태주시강언중의원인과48례중증폐염심력쇠갈전기환인안입선단쌍일분위관찰조(23례)화대조조(25례).2조균급여양료、감측생명체정、항염、항병독、지해평천、화담、한제입량등상규종합치료,관찰조가용소제량서지란간예치료관찰비교2조환인적심솔급호흡전정상적시간、주원시간、림상료효급전구.결과 관찰조심솔급호흡전정상적시간、주원시간여대조조비교[(0.8±0.3)d비(3.8±0.7)d、(1.0±0.5)d비(3.6±0.6)d、(7.1±0.5)d비(8.0±0.4)d],차이균유통계학의의(균P＜0.01) 관찰조총유효솔위100.0％(23/23),대조조총유효솔위56.0％(14/25),2조비교차이유통계학의의(P＜0.05).대조조유7례환인발전위전형심력쇠갈.결론 조기응용소제량서지란간예영유인중증폐염능안전유효지방지심력쇠갈적발생.
Objective To iuvestigate the effects of early administration of small dose cedilanid in infants with severe pneumonia in compensation stage of heart failure.Methods Totally forty-eight infauts with severe pneumonia were divided into observation group (n =23) and control group (n =25).Results The time of cough improvement,heart rate recovery,respiration recovery and duration of hospitalization in the treatment group were significantly shorter than those in the control group [(0.8 ± 0.3) d vs (3.8 ± 0.7) d,(1.0 ± 0.5) d vs (3.6 ± 0.6) d,(7.1 ± 0.5) d vs (8.0 ± 0.4) d] ; there were significant differences (all P ＜ 0.01).The total affective rate of observation group was 100.0％ (23/23) and it was 56.0％ (14/25) in the control group,showing significaut differences (P ＜0.05).There was no adverse reaction in observation group; there were 3 cases suffering from pneumonia,3 cases suffering from pneumonia combined with congenital heart disease; 1 case suffered from severe anemia in control group.Conclusion Application of small dose cedilanid as an early intervention on infants with severe pneumonia can prevent the occurrence of heart failure effectively and safely.
