中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
4期
494-496
,共3页
支气管肺炎%充血性心力衰竭%酚妥拉明
支氣管肺炎%充血性心力衰竭%酚妥拉明
지기관폐염%충혈성심력쇠갈%분타랍명
Bronchopneumonia%Congestive heart failure%Phentolamine
目的 观察酚妥拉明2种给药方法治疗小儿支气管肺炎合并充血性心力衰竭的临床疗效.方法 选取解放军第二五二医院儿科2008年1月至2012年11月治疗的81例小儿支气管肺炎合并充血性心力衰竭患者,完全随机分为酚妥拉明入壶组(24例)、酚妥拉明持续泵入组(30例)和对照组(27例)所有患者给予抗感染、平喘、强心常规治疗,酚妥拉明入壶组采用传统方法酚妥拉明0.5 mg/kg入莫菲滴壶静脉滴注,酚妥拉明持续泵入组采用输液泵静脉滴注,速度为0.6 ～1 μg/(kg·min),疗程均为3 cd观察3组患者临床疗效、咳嗽消失时间、喘息消失时间和肺部哆音消失时间及不良反应.结果 酚妥拉明入壶组与酚妥拉明持续泵入组比较,咳嗽消失时间差异无统计学意义(P＞0.05),喘息消失时间和肺部哕音消失时间比较差异有统计学意义[(6.8±1.1)d比(5.9±0.8)d,(6.8±0.9)d比(6.3±0.9)d,均P＜0.05].酚妥拉明入壶组与酚妥拉明持续泵入组总有效率比较,差异有统计学意义[91.7％ (22/24)比96.7％(29/30)P＜0.05.2组分别与对照组[85.2％(23/27)]比较,差异有统计学意义,(P＜0.05)结论 酚妥拉明以输液泵静脉滴注治疗小儿支气管肺炎合并充血性心力衰竭,肺部哕音和咳喘消失时间缩短,且无鼻阻、烦躁、心率增快等不良反应出现.
目的 觀察酚妥拉明2種給藥方法治療小兒支氣管肺炎閤併充血性心力衰竭的臨床療效.方法 選取解放軍第二五二醫院兒科2008年1月至2012年11月治療的81例小兒支氣管肺炎閤併充血性心力衰竭患者,完全隨機分為酚妥拉明入壺組(24例)、酚妥拉明持續泵入組(30例)和對照組(27例)所有患者給予抗感染、平喘、彊心常規治療,酚妥拉明入壺組採用傳統方法酚妥拉明0.5 mg/kg入莫菲滴壺靜脈滴註,酚妥拉明持續泵入組採用輸液泵靜脈滴註,速度為0.6 ～1 μg/(kg·min),療程均為3 cd觀察3組患者臨床療效、咳嗽消失時間、喘息消失時間和肺部哆音消失時間及不良反應.結果 酚妥拉明入壺組與酚妥拉明持續泵入組比較,咳嗽消失時間差異無統計學意義(P＞0.05),喘息消失時間和肺部噦音消失時間比較差異有統計學意義[(6.8±1.1)d比(5.9±0.8)d,(6.8±0.9)d比(6.3±0.9)d,均P＜0.05].酚妥拉明入壺組與酚妥拉明持續泵入組總有效率比較,差異有統計學意義[91.7％ (22/24)比96.7％(29/30)P＜0.05.2組分彆與對照組[85.2％(23/27)]比較,差異有統計學意義,(P＜0.05)結論 酚妥拉明以輸液泵靜脈滴註治療小兒支氣管肺炎閤併充血性心力衰竭,肺部噦音和咳喘消失時間縮短,且無鼻阻、煩躁、心率增快等不良反應齣現.
목적 관찰분타랍명2충급약방법치료소인지기관폐염합병충혈성심력쇠갈적림상료효.방법 선취해방군제이오이의원인과2008년1월지2012년11월치료적81례소인지기관폐염합병충혈성심력쇠갈환자,완전수궤분위분타랍명입호조(24례)、분타랍명지속빙입조(30례)화대조조(27례)소유환자급여항감염、평천、강심상규치료,분타랍명입호조채용전통방법분타랍명0.5 mg/kg입막비적호정맥적주,분타랍명지속빙입조채용수액빙정맥적주,속도위0.6 ～1 μg/(kg·min),료정균위3 cd관찰3조환자림상료효、해수소실시간、천식소실시간화폐부치음소실시간급불량반응.결과 분타랍명입호조여분타랍명지속빙입조비교,해수소실시간차이무통계학의의(P＞0.05),천식소실시간화폐부홰음소실시간비교차이유통계학의의[(6.8±1.1)d비(5.9±0.8)d,(6.8±0.9)d비(6.3±0.9)d,균P＜0.05].분타랍명입호조여분타랍명지속빙입조총유효솔비교,차이유통계학의의[91.7％ (22/24)비96.7％(29/30)P＜0.05.2조분별여대조조[85.2％(23/27)]비교,차이유통계학의의,(P＜0.05)결론 분타랍명이수액빙정맥적주치료소인지기관폐염합병충혈성심력쇠갈,폐부홰음화해천소실시간축단,차무비조、번조、심솔증쾌등불량반응출현.
Objective To observe the clinical curative effect in children's bronchitis pneumonia accompanied with cardiac failure by the treatment of the two different methods of abstention with phentolamine.Methods Eighty-one cases in children's pneumonia accompanied with cardiac failure were stochastically divided into treatment group 1(24 cases,treated by infusion with phentolamine) and treatment group 2(30 cases treated by continuos pump with phentolamine) and control group(27 cases,without phentolamine).The control group was conventionally treated by anti-infection,antiasthmatic effect and cardiac strength.Based on the treatment above,treatment group 1 took the intravenous injection into murph's dropper with phentolamine,and group 2 took the intravenous infuseion with phentolamine.The clinical efficacy of the three groups of patients,cough disappearance time,wheezing disappearance time,pulmonary rales disappeared time and adverse reactions were observed.Results Cough disappearance time had no significant difference in treatment group 1 and treatment group 2.Wheezing disappeared time and pulmonary rales disappeared time in the treatment group 2 were shorter than those in the treatment group 1 [(5.9±0.8)d vs (6.8±1.1)d,(6.3±0.9)dvs (6.8±0.9)d,P＜0.05].Effective rate in the treatment group 2 was higher than that in the control group and treatment group 1 [96.7％ (26/30) vs 91.7％ (22/24),85.2％ (23/27)]; effective rate in the treatment group 1 was higher than that in the control group; differences were statistically significant(all P ＜0.05).Conclusions Children with bronchial pneumonia and congestive heart failure treated by intravenous drip infusion pump phentolamine,wheezing disappeared time and pulmonary rales disappeared time are shortened.There are no adverse reactions such as nasal resistance,irritability,increased heart rate.
