中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
5期
614-619
,共6页
闻松男%刘念%白融%阮燕菲%李松南%吴晓燕%杜昕%刘小慧%董建增
聞鬆男%劉唸%白融%阮燕菲%李鬆南%吳曉燕%杜昕%劉小慧%董建增
문송남%류념%백융%원연비%리송남%오효연%두흔%류소혜%동건증
心房颤动%QT间期%窦性心律%心电图
心房顫動%QT間期%竇性心律%心電圖
심방전동%QT간기%두성심률%심전도
Atrial fibrillation%QT interval%Sinus rhythm%Electrocardiogram
目的 探讨Bazett、Fridericia和Framingham3种公式对心房颤动QT间期校正的影响.方法 收集30例接受导管射频消融(CA)术的持续性心房颤动患者,以及与心房颤动患者年龄、性别匹配的20例阵发性室上性心动过速(PSVT)患者.收集CA术前、CA术后0.5h的心电图.测量连续3个心动周期QT间期.采用Bazett、Fridericia和Framingham 3种公式校正QT间期.每例患者CA术后的窦性心律维持均未使用抗心律失常药物和/或电复律.所有患者除外药物、严重冠状动脉缺血、近期电转复、电解质紊乱等影响心率校正QT间期的所有因素.结果 心房颤动患者CA术前和术后,心率差异无统计学意义[(89±15)次/min比(82±11)次/min,P=0.06].采用Bazett、Fridericia和Framingham公式校正QT间期,心房颤动患者和PSVT患者术后QTc与术前比较,差异均无统计学意义[心房颤动患者:(436±28) ms比(441±42) ms,P=0.398;(412±27) ms比(413±36) ms,P =0.887; (408±25) ms比(409±31)ms,P =0.762.PSVT患者:(436±17)ms比(437±14) ms,P=0.837;(411±16)ms比(421±13) ms,P=0.151;(412±14)ms比(422±12)ms,P=0.110].应用Bazett、Fridericia和Framingham公式分析心房颤动患者CA术前QTc与RR间期的相关性,相关系数分别为-0.399、-0.088、-0.031.结论 CA本身对QTc无影响.采用Bazett,Fridercia和Framingham 3种公式校正QT间期,持续性心房颤动患者CA术后的QTc无显著性改变.心房颤动患者采用Framingham公式校正QT间期受心动周期的影响更小.
目的 探討Bazett、Fridericia和Framingham3種公式對心房顫動QT間期校正的影響.方法 收集30例接受導管射頻消融(CA)術的持續性心房顫動患者,以及與心房顫動患者年齡、性彆匹配的20例陣髮性室上性心動過速(PSVT)患者.收集CA術前、CA術後0.5h的心電圖.測量連續3箇心動週期QT間期.採用Bazett、Fridericia和Framingham 3種公式校正QT間期.每例患者CA術後的竇性心律維持均未使用抗心律失常藥物和/或電複律.所有患者除外藥物、嚴重冠狀動脈缺血、近期電轉複、電解質紊亂等影響心率校正QT間期的所有因素.結果 心房顫動患者CA術前和術後,心率差異無統計學意義[(89±15)次/min比(82±11)次/min,P=0.06].採用Bazett、Fridericia和Framingham公式校正QT間期,心房顫動患者和PSVT患者術後QTc與術前比較,差異均無統計學意義[心房顫動患者:(436±28) ms比(441±42) ms,P=0.398;(412±27) ms比(413±36) ms,P =0.887; (408±25) ms比(409±31)ms,P =0.762.PSVT患者:(436±17)ms比(437±14) ms,P=0.837;(411±16)ms比(421±13) ms,P=0.151;(412±14)ms比(422±12)ms,P=0.110].應用Bazett、Fridericia和Framingham公式分析心房顫動患者CA術前QTc與RR間期的相關性,相關繫數分彆為-0.399、-0.088、-0.031.結論 CA本身對QTc無影響.採用Bazett,Fridercia和Framingham 3種公式校正QT間期,持續性心房顫動患者CA術後的QTc無顯著性改變.心房顫動患者採用Framingham公式校正QT間期受心動週期的影響更小.
목적 탐토Bazett、Fridericia화Framingham3충공식대심방전동QT간기교정적영향.방법 수집30례접수도관사빈소융(CA)술적지속성심방전동환자,이급여심방전동환자년령、성별필배적20례진발성실상성심동과속(PSVT)환자.수집CA술전、CA술후0.5h적심전도.측량련속3개심동주기QT간기.채용Bazett、Fridericia화Framingham 3충공식교정QT간기.매례환자CA술후적두성심률유지균미사용항심률실상약물화/혹전복률.소유환자제외약물、엄중관상동맥결혈、근기전전복、전해질문란등영향심솔교정QT간기적소유인소.결과 심방전동환자CA술전화술후,심솔차이무통계학의의[(89±15)차/min비(82±11)차/min,P=0.06].채용Bazett、Fridericia화Framingham공식교정QT간기,심방전동환자화PSVT환자술후QTc여술전비교,차이균무통계학의의[심방전동환자:(436±28) ms비(441±42) ms,P=0.398;(412±27) ms비(413±36) ms,P =0.887; (408±25) ms비(409±31)ms,P =0.762.PSVT환자:(436±17)ms비(437±14) ms,P=0.837;(411±16)ms비(421±13) ms,P=0.151;(412±14)ms비(422±12)ms,P=0.110].응용Bazett、Fridericia화Framingham공식분석심방전동환자CA술전QTc여RR간기적상관성,상관계수분별위-0.399、-0.088、-0.031.결론 CA본신대QTc무영향.채용Bazett,Fridercia화Framingham 3충공식교정QT간기,지속성심방전동환자CA술후적QTc무현저성개변.심방전동환자채용Framingham공식교정QT간기수심동주기적영향경소.
Objective To compare the QT interval (QTc) during atrial tbrillation (AF).Methods A total of 30 patients with persistent AF receiving catheter ablation (CA) were enrolled.We selected 20 sex-and agematched patients with paroxysmal supraventricular tachycardia(PSVT) who underwent CA.None of the patients had factors that might have impact on QT interval including drugs,severe ischemia,electrode disorders and recent cardioversion.QT interval was measured 1 day before CA under AF rhythm and immediate after CA under SR.At each measurement,at least 3 consecutive QRS complexes were taken.QTc was corrected with the cardiac cycle length and calculated using three formulas:Bazett,Fridericia and Framingham.Sinus rhythm (SR) was restored spontaneously by CA without applying any medication or cardioversion.Results Average heart rate was similar during AF and SR[(89 ± 15) times/min vs (82 ± 11) times/min,P =0.06].Regardless of the formula used to correct QT interval,a self-controlled comparison indicated that there was no signifcant difference of QTc before and after CA in patients with PSVT[(436 ± 17)ms vs (437 ± 14)ms,P =0.837; (411 ± 16)ms vs (421 ± 13)ms,P =0.151 ; (412 ± 14) ms vs (422 ± 12) ms,P =0.110] and there was no signifcant difference of QTc during AF and SR[(441 ±42)ms vs (436 ±28)ms,P =0.398;(412 ±27)ms vs (413 ±36)ms,P=0.887;(408 ±25)ms vs (409 ± 31)ms,P =0.762].However,during AF,QTc showed much less strong correlation coefficients with cardiac cycle length when assessed by Framingham formula (correlation coeffcients:-0.399,-0.088,-0.031).Conclusions QTc during persistent AF is not different from that during SR when QT interval is corrected by using Bazett,Fridericia or Framingham formula.During AF,QTc is seldom influenced by cardiac cycle length when Framingham formula is applied.
