中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
5期
691-693
,共3页
廖金平%董德胜%舒振云%宋斌
廖金平%董德勝%舒振雲%宋斌
료금평%동덕성%서진운%송빈
严重多发伤%急诊科%早期镇痛
嚴重多髮傷%急診科%早期鎮痛
엄중다발상%급진과%조기진통
Severe multiple trauma%Emergency department%Early analgesia treatment
目的 探讨严重多发伤患者在急诊科早期进行镇痛治疗时不同镇痛药物的治疗效果与不良反应.方法 选取解放军第九八医院急诊科严重多发伤患者123例,采取随机数字表法分为盐酸哌替啶组40例、地佐辛组41例、酮咯酸氨丁三醇组42例.3组入院时分别肌内注射盐酸哌替啶注射液75 mg、地佐辛注射液7.5 mg、酮咯酸氨丁三醇注射液60 mg.观察比较3组镇痛效果和不良反应.结果 3组镇痛总有效率均为100％,差异无统计学意义(P＞0.05).地佐辛组和酮咯酸氨丁三醇组的总不良反应发生率[14.6％ (6/41),9.5％ (4/42)]明显低于盐酸哌替啶组(75.0％,30/40),组间比较差异有统计学意义(P＜0.05).结论 严重多发伤患者在急诊科早期进行镇痛治疗可获得满意的疗效.在镇痛药选择上应首选镇痛作用强、不良反应低的地佐辛,其次是酮咯酸氨丁三醇,应减少盐酸哌替啶等阿片类镇痛药物的使用.
目的 探討嚴重多髮傷患者在急診科早期進行鎮痛治療時不同鎮痛藥物的治療效果與不良反應.方法 選取解放軍第九八醫院急診科嚴重多髮傷患者123例,採取隨機數字錶法分為鹽痠哌替啶組40例、地佐辛組41例、酮咯痠氨丁三醇組42例.3組入院時分彆肌內註射鹽痠哌替啶註射液75 mg、地佐辛註射液7.5 mg、酮咯痠氨丁三醇註射液60 mg.觀察比較3組鎮痛效果和不良反應.結果 3組鎮痛總有效率均為100％,差異無統計學意義(P＞0.05).地佐辛組和酮咯痠氨丁三醇組的總不良反應髮生率[14.6％ (6/41),9.5％ (4/42)]明顯低于鹽痠哌替啶組(75.0％,30/40),組間比較差異有統計學意義(P＜0.05).結論 嚴重多髮傷患者在急診科早期進行鎮痛治療可穫得滿意的療效.在鎮痛藥選擇上應首選鎮痛作用彊、不良反應低的地佐辛,其次是酮咯痠氨丁三醇,應減少鹽痠哌替啶等阿片類鎮痛藥物的使用.
목적 탐토엄중다발상환자재급진과조기진행진통치료시불동진통약물적치료효과여불량반응.방법 선취해방군제구팔의원급진과엄중다발상환자123례,채취수궤수자표법분위염산고체정조40례、지좌신조41례、동각산안정삼순조42례.3조입원시분별기내주사염산고체정주사액75 mg、지좌신주사액7.5 mg、동각산안정삼순주사액60 mg.관찰비교3조진통효과화불량반응.결과 3조진통총유효솔균위100％,차이무통계학의의(P＞0.05).지좌신조화동각산안정삼순조적총불량반응발생솔[14.6％ (6/41),9.5％ (4/42)]명현저우염산고체정조(75.0％,30/40),조간비교차이유통계학의의(P＜0.05).결론 엄중다발상환자재급진과조기진행진통치료가획득만의적료효.재진통약선택상응수선진통작용강、불량반응저적지좌신,기차시동각산안정삼순,응감소염산고체정등아편류진통약물적사용.
Objective To evaluate the effect of early analgesia treatment on severe multiple trauma in the emergency department.Methods Totally 123 patients with severe multiple trauma were randomly divided into hydrochloride pethidine group (40 cases),dezocine group (41 cases) and ketorolac tromethamine group (42 cases).Three groups were given hydrochloride pethidine injection 75 mg,dezocine injection 7.5 mg and ketorolac tromethamine 60 mg respectively.Analgesic effect and adverse reactions of three groups were observed.Results The total analgesic rate was 100％ ; there was no statistically significant difference (P ＞ 0.05).The total rate of adverse reaction of dezocine group and ketorolac tromethamine group were obviously less than that of hydrochloride pethidine group (14.6％,9.5％ vs 75.0％) ; the difference was statistically significant (P ＜ 0.05).Conclusions The early analgesia treatment can obtain satisfactory curative effect for severe multiple injuries in the emergency department.Low adverse reaction of dezocine ketorolac tromethamine and dezocine should reduce the use of opioids such as pethidine hydrochloride.
