中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
5期
713-715
,共3页
子宫肌瘤%妇科再造胶囊%米非司酮
子宮肌瘤%婦科再造膠囊%米非司酮
자궁기류%부과재조효낭%미비사동
Hysteromyoma%Fuke Zaizao capsule%Mifepristone
目的 观察妇科再造胶囊联合米非司酮对子宫肌瘤的临床疗效.方法 选取2011年3月至2013年3月贵阳中医学院第二附属医院子宫肌瘤患者160例,完全随机分为观察组和对照组,各80例.观察组给予妇科再造胶囊联合米非司酮治疗,对照组仅给予米非司酮,观察治疗效果及性激素[血清孕酮、黄体生成素、促卵泡激素及雌二醇]水平的变化.结果 观察组总有效率[93.8％(75/80)]高于对照组[75.0％ (60/80)],2组总有效率差异有统计学意义(P＜0.05).2组治疗后雌二醇、孕酮水平均明显低于本组治疗前,治疗前后比较,差异有统计学意义[雌二醇水平:观察组治疗前后分别为(373±54)、(163±46) pmol/L,对照组治疗前后分别为(370±36)、(221±55) pmol/L;孕酮水平:观察组治疗前后分别为(33±4)、(9±3) μg/L,对照组治疗前后分别为(34±4)、(14±3)μg/L;均P＜0.05];治疗后,观察组雌二醇、孕酮水平明显低于对照组(均P＜0.05).2组患者均无明显不良反应发生.结论 妇科再造胶囊联合米非司酮治疗子宫肌瘤疗效确切,安全性好.
目的 觀察婦科再造膠囊聯閤米非司酮對子宮肌瘤的臨床療效.方法 選取2011年3月至2013年3月貴暘中醫學院第二附屬醫院子宮肌瘤患者160例,完全隨機分為觀察組和對照組,各80例.觀察組給予婦科再造膠囊聯閤米非司酮治療,對照組僅給予米非司酮,觀察治療效果及性激素[血清孕酮、黃體生成素、促卵泡激素及雌二醇]水平的變化.結果 觀察組總有效率[93.8％(75/80)]高于對照組[75.0％ (60/80)],2組總有效率差異有統計學意義(P＜0.05).2組治療後雌二醇、孕酮水平均明顯低于本組治療前,治療前後比較,差異有統計學意義[雌二醇水平:觀察組治療前後分彆為(373±54)、(163±46) pmol/L,對照組治療前後分彆為(370±36)、(221±55) pmol/L;孕酮水平:觀察組治療前後分彆為(33±4)、(9±3) μg/L,對照組治療前後分彆為(34±4)、(14±3)μg/L;均P＜0.05];治療後,觀察組雌二醇、孕酮水平明顯低于對照組(均P＜0.05).2組患者均無明顯不良反應髮生.結論 婦科再造膠囊聯閤米非司酮治療子宮肌瘤療效確切,安全性好.
목적 관찰부과재조효낭연합미비사동대자궁기류적림상료효.방법 선취2011년3월지2013년3월귀양중의학원제이부속의원자궁기류환자160례,완전수궤분위관찰조화대조조,각80례.관찰조급여부과재조효낭연합미비사동치료,대조조부급여미비사동,관찰치료효과급성격소[혈청잉동、황체생성소、촉란포격소급자이순]수평적변화.결과 관찰조총유효솔[93.8％(75/80)]고우대조조[75.0％ (60/80)],2조총유효솔차이유통계학의의(P＜0.05).2조치료후자이순、잉동수평균명현저우본조치료전,치료전후비교,차이유통계학의의[자이순수평:관찰조치료전후분별위(373±54)、(163±46) pmol/L,대조조치료전후분별위(370±36)、(221±55) pmol/L;잉동수평:관찰조치료전후분별위(33±4)、(9±3) μg/L,대조조치료전후분별위(34±4)、(14±3)μg/L;균P＜0.05];치료후,관찰조자이순、잉동수평명현저우대조조(균P＜0.05).2조환자균무명현불량반응발생.결론 부과재조효낭연합미비사동치료자궁기류료효학절,안전성호.
Objective To investigate the effect of Fuke Zaizao capsule plus mifepristone on hysteromyoma.Methods A total of 160 cases with hysteromyoma collected from the outpatient department of gynecology during Mar.2011 to Mar.2013 were randomly divided into observation group (n =80) and control group (n =80).The observation group were given Fuke Zaizao capsule plus mifepristone and the control group were treated with only mifepristone.The outcomes were investigated and compared between the tao groups.Results The total effective rote was 93.8％ (75/80) in observation group,higher than 75.0％ (60/80) in control group (P ＜0.05).The levels of estradiol and progesterone were lower than those before treatment in both two groups[the observation group before and after treatment with estradiol levels respectively:(373 ± 54)pmol/L,(163 ± 46)pmol/L,the control group before and after treatment with estradiol levels respectivdy:(370 ±36) pmol/L,(221 ±55)pmol/L; the observation group before and after treatment with progesterone levels respectively:(33 ± 4) μg/L,(9 ± 3) μg/L;the control group before and after treatment with progesterone levels respectively:(34 ± 4) μg/L,(14 ± 3) μg/L;all P ＜ 0.05] ; the two groups also had significant differences in the levels of estradiol and progesterone after treatment (P ＜ 0.05).There were no serious adverse reactions in either group.Conclusion The therapy of Fuke Zaizao capsule plus mifepristone in the treatment of hysteromyoma is safe and has a high effective rate.
