CAJ | 학술논문

目的探讨透明质酸修护贴敷料在Q开关激光术后皮肤创面修复中的有效性和安全性.方法面部色素性疾病患者66例,用Q开关脉冲激光治疗后,将患者分为试验组(22例)、对照组A(22例)和对照组B(22例).试验组使用透明质酸修护贴敷料,对照组A用活泉水面膜,对照组B用蒸馏水面膜.激光术后即刻外敷受试品或对照品15 min,以后每晚外敷15 min,连续14 d；分别于激光术后首日、第3、7、14天对受试部位红斑、水肿、灼热等炎症反应进行半定量判定.同时比较3组患者创面恢复时间及对敷料的满意度.结果透明质酸修护贴敷料和活泉水面膜改善激光术后皮肤红斑、水肿、灼热等症状优于蒸馏水面膜(P＜0.05).激光术后,患者创面清洁度、湿润度、光滑度、舒缓程度和总体满意度,透明质酸修护贴敷料优于活泉水面膜和蒸馏水面膜(P＜0.05).结论透明质酸修护贴敷料用于激光术后护理可改善急性炎症反应、提高创而清洁度、湿润度、光滑度.
목적 탐토투명질산수호첩부료재Q개관격광술후피부창면수복중적유효성화안전성.방법 면부색소성질병환자66례,용Q개관맥충격광치료후,장환자분위시험조(22례)、대조조A(22례)화대조조B(22례).시험조사용투명질산수호첩부료,대조조A용활천수면막,대조조B용증류수면막.격광술후즉각외부수시품혹대조품15 min,이후매만외부15 min,련속14 d；분별우격광술후수일、제3、7、14천대수시부위홍반、수종、작열등염증반응진행반정량판정.동시비교3조환자창면회복시간급대부료적만의도.결과 투명질산수호첩부료화활천수면막개선격광술후피부홍반、수종、작열등증상우우증류수면막(P＜0.05).격광술후,환자창면청길도、습윤도、광활도、서완정도화총체만의도,투명질산수호첩부료우우활천수면막화증류수면막(P＜0.05).결론 투명질산수호첩부료용우격광술후호리가개선급성염증반응、제고창이청길도、습윤도、광활도.
Objective To evaluate the effectiveness and safety of a sodium hyaluronate-containing dressing for skin wound healing after Q-switched laser therapy.Methods Sixty-six patients with facial pigmentary disorders were enrolled in this study.After treatment with Q-switched laser,the patients were randomly and equally divided into three groups to apply a sodium hyaluronate-containing dressing,a thermal spring water-containing facial mask and a distilled water-containing facial mask respectively.The dressing or facial masks were externally applied to the face for 15 minutes once immediately after the laser therapy,then,once every night for 14 consecutive days.Inflammatory responses,such as erythema,edema and burning sensation,were measured semi-quantitatively on day 1,3,7 and 14 separately after the laser therapy.The time for skin wound healing and degree of patients' satisfaction were compared among these groups by chi-square test and rank sum test,respectively.Results The sodium hyaluronate-containing dressing and thermal spring watercontaing facial mask were superior to the distilled water-containing facial mask in the improvement of erythema,edema and burning sensation after the laser therapy (all P ＜ 0.05).Compared with the patients applying the thermal spring water-containg facial mask and those applying the distilled water-containing facial mask,those applying the sodium hyaluronate-containing dressing felt better,with significantly increased skin cleanliness,humidity,smoothness,confort degree and overall satisfaction (all P ＜ 0.05).Conclusion The sodium hyaluronate-containing dressing is effective for improving acute inflammatory responses and increasing skin cleanliness,humidity and smoothness after laser therapy.