中华皮肤科杂志
中華皮膚科雜誌
중화피부과잡지
Chinese Journal of Dermatology
2014年
9期
660-662
,共3页
尖锐湿疣%儿童%人乳头状瘤病毒
尖銳濕疣%兒童%人乳頭狀瘤病毒
첨예습우%인동%인유두상류병독
Condylomata acuminata%Child%Human papillomavirus
目的 检测山东省潍坊市尖锐湿疣患儿中人乳头瘤病毒(HPV)感染情况及基因亚型.方法 采用基因扩增技术及导流杂交分型技术,对24例患儿疣体的HPV进行检测分型.结果 24例尖锐湿疣检出23例HPV阳性,阳性率95.8％,20例单一型HPV感染占87.0％,混合感染型3例占13.0％;感染型别依次是HPV6(9/23),HPV16(6/23),HPV 11 (5/23),HPV58(3/23),HPV18(2/23),HPV53(1/23).结论 该地区尖锐湿疣患儿HPV型别以6、16、11、58、18为主,患儿感染HPV型别与生活中密切接触者感染的型别相似.
目的 檢測山東省濰坊市尖銳濕疣患兒中人乳頭瘤病毒(HPV)感染情況及基因亞型.方法 採用基因擴增技術及導流雜交分型技術,對24例患兒疣體的HPV進行檢測分型.結果 24例尖銳濕疣檢齣23例HPV暘性,暘性率95.8％,20例單一型HPV感染佔87.0％,混閤感染型3例佔13.0％;感染型彆依次是HPV6(9/23),HPV16(6/23),HPV 11 (5/23),HPV58(3/23),HPV18(2/23),HPV53(1/23).結論 該地區尖銳濕疣患兒HPV型彆以6、16、11、58、18為主,患兒感染HPV型彆與生活中密切接觸者感染的型彆相似.
목적 검측산동성유방시첨예습우환인중인유두류병독(HPV)감염정황급기인아형.방법 채용기인확증기술급도류잡교분형기술,대24례환인우체적HPV진행검측분형.결과 24례첨예습우검출23례HPV양성,양성솔95.8％,20례단일형HPV감염점87.0％,혼합감염형3례점13.0％;감염형별의차시HPV6(9/23),HPV16(6/23),HPV 11 (5/23),HPV58(3/23),HPV18(2/23),HPV53(1/23).결론 해지구첨예습우환인HPV형별이6、16、11、58、18위주,환인감염HPV형별여생활중밀절접촉자감염적형별상사.
Objective To detect human papilloma virus (HPV) and to determine its genotype in children with condyloma acuminatum (CA) in Weifang city,Shandong province.Methods Swab specimens were collected from the surface of lesions of 24 children with CA.PCR/flow-through hybridization assay was performed to detect HPV and determine its genotypes in these specimens.Results Among the 24 specimens,95.8％ (23/24) were positive for HPV.Of the HPV-positive specimens,87.0％ (20/23) harbored single type of HPV,and 13.0％ (3/23) multiple types of HPV.The most common genotype was HPV6(9/23),followed by HPV16 (6/23),HPV11 (5/23),HPV58 (3/23),HPV18 (2/23),and HPV53 (1/23).Conclusions HPV 6,16,11,58 and 18 prevail in children patients with CA in Weifang city,Shandong province.Additionally,the HPV genotypes in children patients are similar to those in their close contacts.
